In vivo selection of sFv from phage display libraries

Journal of Immunological Methods

Volumn 239, Issue 1-2, 2000, Pages 137-151

  Johns, Michael ^a   George, Andrew J T ^a   Ritter, Mary A ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

In vivo selection; Phage display; Thymus

Indexed keywords

VIRUS VECTOR;

ANTIBODY PRODUCTION; ANTIGEN EXPRESSION; ARTICLE; BACTERIOPHAGE M13; BIOTECHNOLOGY; DNA LIBRARY; ENDOTHELIUM CELL; ESCHERICHIA COLI; GENETIC SELECTION; PRIORITY JOURNAL; TECHNIQUE; THYMUS; VASCULAR ENDOTHELIUM;

ANIMALS; BACTERIOPHAGE M13; ENDOTHELIUM; GENE EXPRESSION; IMMUNOGLOBULIN FRAGMENTS; KINETICS; MICE; PEPTIDE LIBRARY; PROTO-ONCOGENE PROTEINS C-MYC; VIRION;

EID: 0034717218     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-1759(00)00152-6     Document Type: Article

References (37)

1. Arap W., Pasqualini R., Ruoslahti E. Cancer treatment by targeted drug delivery to tumour vasculature in a mouse model. Science. 279:1998;377-380.
2. Aurrand-Lions M., Galland F., Bazin H., Zakharyev V.M., Imhof B.A., Naquet P. Vanin-1, a novel GPI-linked perivascular molecule involved in thymus homing. Immunity. 5:(5):1996;391-405.
3. Barclay A.N., Brown M.H., Law S.K.A., McKnight A.J., Tomlinson M.G., van der Merwe P.A. The Leukocyte Antigen Factsbook. 2nd Edition :1997;Academic Press, Oxford.
4. Barbas C.D., Kang A.S., Lerner R.A., Lerner R.A. Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc Natl Acad Sci USA. 88:(18):1991;7978-7982.
5. Berlin C., Bargatze R.F., Campbell J.J., Von Andrian U.H., Szabo M.C., Hasslen R.D., Berg E.L., Erlandsen S.L., Butcher E.C. α4 Integrins mediate lymphocyte attachment and rolling under physiologic flow. Cell. 80:1995;413-422.
6. Borsum T., Hagen I., Henriksen T., Carlander B. Alterations in the protein composition and surface structure of human endothelial cells during growth of primary cultures. Atherosclerosis. 44:1982;367-378.
7. Boyd R.L., Tucek C.L., Godfrey D.I., Izon D.J., Wilson T.J., Davidson N.J., Bean A.G., Ladyman H.M., Ritter M.A., Hugo P. The thymic microenvironment. Immunol. Today. 14:1993;445-459.
8. Butcher E.C. Overview: cell adhesion receptors in the immune system. Herzenberg L.A., Weir D.M., Herzenberg L.A., Blackwell C. 5th Edition Weirs Handbook of Experimental Immunology. Vol. 2. Cell surface and messenger molecules of the immune system:1996;67.1-67.7 Blackwell.
9. Carter P., Bedouelle M., Winter G. Improved oligonucleotide site-directed mutagenesis using M13 vectors. Nucl. Acids Res. 13:1985;4431-4443.
10. Coltey M., Jotereau F.V., Le Dourarin N.M. Evidence for cyclic renewal of lymphocyte precursor cells in the embryonic chick thymus. Cell Diff. 22:1987;71-82.
11. Coltey M., Bucy R.P., Chen C.H., Cihak J., Losch U., Char D., Le-Dourarin N.M., Cooper M.D. Analysis of the first two waves of thymus homing stem cells and their T cell progeny in chick-quail chimeras. J. Exp. Med. 170:1989;543-557.
12. de Kruif J., Boel E., Logtenberg T. Selection and application of human single chain Fv antibody fragments from a semi-synthetic phage antibody display library with designed CDR3 regions. J. Mol. Biol. 248:1995;97-105.
13. de Kruif J., Terstappen L., Boel E., Logtenberg T. Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library. Proc. Natl. Acad. Sci. USA. 92:1995;3938.
14. de Maagd R.A., MacKenzie W.A., Schuurman H-J., Ritter M.A., Price K.M., Broekhuizen R., Kater L. The human thymus microenvironment: heterogeneity detected by monoclonal anti-epithelial cell antibodies. Immunology. 54:1985;745-754.
15. Fontaine-Perus J.C., Calman F.M., Kaplan C., LeDouarin N.M. Seeding of the 10-day mouse embryo thymic rudiment by lymphocyte precursors in vitro. J. Immunol. 126:1981;2310-2316.
16. Geier M.R., Trigg M.E., Merril C.R. Fate of bacteriophage lambda in non-immune germ-free mice. Nature. 246:1973;221-223.
17. Gibson, 1984. Ph.D. Thesis, University of Cambridge.
18. Griffiths A.D., Williams S.C., Hartley O., Tomlinson I.M., Waterhouse P., Crosby W.L., Kontermann R.E., Jones P.T., Low N.M., Allison T.J., Prospero T.D., Hoogenboom H.R., Nissim A., Cox J.P.L., Harrison J.L., Zaccolo M., Gherardi E., Winter G. Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13:1994;3245-3260.
19. Hoogenboom H.R., Griffiths A.D., et al. Multi-subunit proteins on the surface of filamentous phage: methodologies of displaying antibody (Fab) heavy and light chains. Nucl. Acids Res. 19:(15):1991;4133-4137.
20. Hoogenboom H.R., Winter G. By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro. J. Mol. Biol. 227:1992;381-388.
21. Jotereau F.V., Houssaint E., Le-Douarin N.M. Lymphoid stem cell homing to the early thymic primordium of the avian embryo. Eur. J. Immunol. 10:1980;620-627.
22. Jotereau F.V., Le-Douarin N.M. Demonstration of a cyclic renewal of the lymphocyte precursor cells in the quail thymus during embryonic and perinatal life. J. Immunol. 129:1982;1869-1877.
23. Kraal G., Breel M., Janse M., Bruin G. Langerhans cells, veiled cells and interdigitating cells in the mouse recognised by a monoclonal antibody. J. Exp. Med. 163:1986;981-997.
24. Kraal G., Mebius R.E. High endothelial venules: Lymphocyte traffic control and controlled traffic. Adv. Immunol. 65:1996;347-395.
25. Marks J.D., Hoogenboom H.R., Bonnert T.P., McCafferty J., Griffiths A.D., Winter G. By passing immunisation: Human antibodies from V-gene libraries diplayed on phage. J. Mol. Biol. 222:1991;581-597.
26. McCafferty J., Griffiths A.D., Winter G., Chiswell D.J. Phage antibodies: filamentous phage displaying antibody variable domains. Nature. 348:1990;552-554.
27. Mutin M., Dignat-George F., Sampol J. Immunologic phenotype of cultured endothelial cells: quantitative analysis of cell surface molecules. Tissue Antigens. 50:1997;449-458.
28. Nissim A., Hoogenboom H.R., Tomlinson I.M., Flynn G., Midgley C., Lane D., Winter G. Antibody fragments from a "single pot' phage display library as immunochemical reagents. EMBO J. 13:1994;692-698.
29. Okamoto N., Kennedy S.D., Barron-Casella E.A., Casella J.F., Inoko H., Kickler T.S. Identification of a heavy chain antibody fragment directed against human platelet alloantigen 1a by phage display library. Tissue Antigens. 51:1998;156-163.
30. Palmer D.B., George A.J.T., Ritter M.A. Selection of antibodies to cell surface determinants on mouse thymic epithelial cells using a phage display library. Immunology. 91:1997;473-478.
31. Palmer D.B., Crompton T., Marandi M.B., George A.J.T., Ritter M.A. Intrathymic function of the cortical epithelial cell surface antigen gp200-MR6 single-chain antibodies to evolutionarily conserved determinants disrupt mouse thymus development. Immunology. 96:1999;236-245.
32. Pasqualini R., Ruoslahti E. Organ targeting in vivo using phage display peptide libraries. Nature. 380:1996;364-366.
33. Pasqualini R., Koivunen E., Ruoslahti E. αV integrins as receptors for tumour targeting by circulating ligands. Nature Biotech. 15:1997;542-546.
34. Reza J.N., Ritter M.A. Differential expression of adhesion molecules within the human thymus. Dev. Immunol. 4:1994;55-64.
35. Ritter M.A., Boyd R.L. Development in the thymus: it takes two to tango. Immunol. Today. 14:1993;462-469.
36. Rajotte D., Arap W., Hagedorn M., Koivunen E., Pasqualini R., Ruoslahti E. Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. J. Clin. Invest. 102:(2):1998;430-437.
37. Siegal D.L., Chang T.Y., Russell S.L., Bunya U.Y. Isolation of cell surface-specific human monoclonal antibodies using phage display and magnetically activated cell sorting: applications in immunohematology. J. Immunol. Meth. 206:1997;73-85.