Peptides selected for binding to clotted plasma accumulate in tumor stroma and wounds

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 8, 2006, Pages 2800-2804

  Pilch, Jan ^a   Brown, Darren M ^a,d   Komatsu, Masanobu ^a,e   Järvinen, Tero A H ^a   Yang, Meng ^b   Peters, David ^a,f   Hoffman, Robert M ^b,c   Ruoslahti, Erkki ^a  

^a BURNHAM INSTITUTE   (United States)

^b ANTICANCER INC   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d BIOGEN   (United States)

^e University of Alabama at Birmingham   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Fibrin; Fibronectin; Imaging; Phage display; Tumor targeting

Indexed keywords

CLT1 PEPTIDE; CLT2 PEPTIDE; FIBRIN; FIBRINOGEN; FIBRONECTIN; PEPTIDE; PEPTIDE LIBRARY; PLASMA PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INJURY; ARTICLE; BINDING SITE; BLOOD CLOTTING; CANCER MODEL; COMPLEX FORMATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; EXTRAVASCULAR SPACE; FLUORESCENCE; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; MOUSE; MUSCLE INJURY; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SKELETAL MUSCLE; SKIN INJURY; STROMA; TUMOR; WOUND;

ANIMALS; BLOOD COAGULATION; CELL LINE, TUMOR; FIBRIN; FIBRONECTINS; HUMANS; MICE; MICE, KNOCKOUT; NEOPLASMS; PEPTIDE LIBRARY; PEPTIDES, CYCLIC; TISSUE DISTRIBUTION; WOUNDS AND INJURIES;

ANIMALIA;

EID: 33644508000     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0511219103     Document Type: Article

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