-
1
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash, J., P.C. Maisonpierre, D. Compton, et al. 1999. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 284 : 1994 1998.
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
-
2
-
-
0029844435
-
Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice
-
&
-
Coussens, L.M., D. Hanahan & J.M. Arbeit. 1996. Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice. Am. J. Pathol. 149 : 1899 1917.
-
(1996)
Am. J. Pathol.
, vol.149
, pp. 1899-1917
-
-
Coussens, L.M.1
Hanahan, D.2
Arbeit, J.M.3
-
3
-
-
0035821293
-
Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells
-
Hattori, K., S. Dias, B. Heissig, et al. 2001. Vascular endothelial growth factor and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J. Exp. Med. 193 : 1005 1014.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1005-1014
-
-
Hattori, K.1
Dias, S.2
Heissig, B.3
-
4
-
-
0033986273
-
Circulating endothelial precursors: Mystery, reality, and promise [comment]
-
Rafii, S. 2000. Circulating endothelial precursors: mystery, reality, and promise [comment]. J. Clin. Invest. 105 : 17 19.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 17-19
-
-
Rafii, S.1
-
5
-
-
0034531951
-
Endothelial cells of tumor vessels: Abnormal but not absent
-
&
-
McDonald, D.M. & A.J. Foss. 2000. Endothelial cells of tumor vessels: abnormal but not absent. Cancer Metast. Rev. 19 : 109 120.
-
(2000)
Cancer Metast. Rev.
, vol.19
, pp. 109-120
-
-
McDonald, D.M.1
Foss, A.J.2
-
6
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
&
-
Carmeliet, P. & R.K. Jain. 2000. Angiogenesis in cancer and other diseases. Nature 407 : 249 257.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
7
-
-
0036488496
-
Specialization of tumour vasculature
-
Ruoslahti, E. 2002. Specialization of tumour vasculature. Nat. Rev. Cancer. 2 : 83 90.
-
(2002)
Nat. Rev. Cancer.
, vol.2
, pp. 83-90
-
-
Ruoslahti, E.1
-
8
-
-
0034682892
-
Genes expressed in human tumor endothelium [see comments]
-
St. Croix, B., C. Rago, V. Velculescu, et al. 2000. Genes expressed in human tumor endothelium [see comments]. Science 289 : 1197 1202.
-
(2000)
Science
, vol.289
, pp. 1197-1202
-
-
St. Croix, B.1
Rago, C.2
Velculescu, V.3
-
9
-
-
2942529235
-
Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy [see comment]
-
Oh, P., Y. Li, J. Yu, et al. 2004. Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy [see comment]. Nature 429 : 629 635.
-
(2004)
Nature
, vol.429
, pp. 629-635
-
-
Oh, P.1
Li, Y.J.2
Yu3
-
11
-
-
24944535233
-
Molecular profiling of heart endothelial cells
-
&
-
Zhang, L., J.A. Hoffman & E. Ruoslahti. 2005. Molecular profiling of heart endothelial cells. Circulation 112 : 1601 1611.
-
(2005)
Circulation
, vol.112
, pp. 1601-1611
-
-
Zhang, L.1
Hoffman, J.A.2
Ruoslahti, E.3
-
12
-
-
0037022366
-
Targeting the prostate for destruction through a vascular address
-
Arap, W., W. Haedicke, M. Bernasconi, et al. 2002. Targeting the prostate for destruction through a vascular address. Proc. Natl. Acad. Sci. USA 99 : 1527 1531.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1527-1531
-
-
Arap, W.1
Haedicke, W.2
Bernasconi, M.3
-
13
-
-
0032528192
-
Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display
-
Rajotte, D., W. Arap, M. Hagedorn, et al. 1998. Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. J. Clin. Invest. 102 : 430 437.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 430-437
-
-
Rajotte, D.1
Arap, W.2
Hagedorn, M.3
-
14
-
-
0029932458
-
Organ targeting in vivo using phage display peptide libraries
-
&
-
Pasqualini, R. & E. Ruoslahti. 1996. Organ targeting in vivo using phage display peptide libraries. Nature 380 : 364 366.
-
(1996)
Nature
, vol.380
, pp. 364-366
-
-
Pasqualini, R.1
Ruoslahti, E.2
-
15
-
-
0035168461
-
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature
-
Gerlag, D.M., E. Borges, P.P. Tak, et al. 2001. Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature. Arthritis Res. 3 : 357 361.
-
(2001)
Arthritis Res.
, vol.3
, pp. 357-361
-
-
Gerlag, D.M.1
Borges, E.2
Tak, P.P.3
-
16
-
-
0037188542
-
A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo
-
Porkka, K., P. Laakkonen, J.A. Hoffman, et al. 2002. A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo. Proc. Natl. Acad. Sci. USA 99 : 7444 7449.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7444-7449
-
-
Porkka, K.1
Laakkonen, P.2
Hoffman, J.A.3
-
17
-
-
0036063778
-
A tumor-homing peptide with a targeting specificity related to lymphatic vessels
-
Laakkonen, P., K. Porkka, J.A. Hoffman, et al. 2002. A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat. Med. 8 : 751 755.
-
(2002)
Nat. Med.
, vol.8
, pp. 751-755
-
-
Laakkonen, P.1
Porkka, K.2
Hoffman, J.A.3
-
18
-
-
0030940283
-
Alpha v integrins as receptors for tumor targeting by circulating ligands [see comments]
-
&
-
Pasqualini, R., E. Koivunen & E. Ruoslahti. 1997. Alpha v integrins as receptors for tumor targeting by circulating ligands [see comments]. Nat. Biotechnol. 15 : 542 546.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 542-546
-
-
Pasqualini, R.1
Koivunen, E.2
Ruoslahti, E.3
-
19
-
-
0033564799
-
NG2 proteoglycan-binding peptides target tumor neovasculature
-
Burg, M.A., R. Pasqualini, W. Arap, et al. 1999. NG2 proteoglycan-binding peptides target tumor neovasculature. Cancer Res. 59 : 2869 2874.
-
(1999)
Cancer Res.
, vol.59
, pp. 2869-2874
-
-
Burg, M.A.1
Pasqualini, R.2
Arap, W.3
-
20
-
-
0344185348
-
Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
-
Joyce, J.A., P. Laakkonen, M. Bernasconi, et al. 2003. Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell. 4 : 393 403.
-
(2003)
Cancer Cell.
, vol.4
, pp. 393-403
-
-
Joyce, J.A.1
Laakkonen, P.2
Bernasconi, M.3
-
21
-
-
0344309914
-
Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma
-
Hoffman, J.A., E. Giraudo, M. Singh, et al. 2003. Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma. Cancer Cell. 4 : 383 391.
-
(2003)
Cancer Cell.
, vol.4
, pp. 383-391
-
-
Hoffman, J.A.1
Giraudo, E.2
Singh, M.3
-
22
-
-
2942668041
-
Lymphatic vasculature: Development, molecular regulation and role in tumor metastasis and inflammation
-
Saharinen, P., T. Tammela, M.J. Karkkainen, et al. 2004. Lymphatic vasculature: development, molecular regulation and role in tumor metastasis and inflammation. Trends Immunol. 25 : 387 395.
-
(2004)
Trends Immunol.
, vol.25
, pp. 387-395
-
-
Saharinen, P.1
Tammela, T.2
Karkkainen, M.J.3
-
23
-
-
0037140120
-
VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors
-
Mattila, M.M., J.K. Ruohola, T. Karpanen, et al. 2002. VEGF-C induced lymphangiogenesis is associated with lymph node metastasis in orthotopic MCF-7 tumors. Int. J. Cancer. 98 : 946 951.
-
(2002)
Int. J. Cancer.
, vol.98
, pp. 946-951
-
-
Mattila, M.M.1
Ruohola, J.K.2
Karpanen, T.3
-
24
-
-
0035122537
-
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis [see comments]
-
Skobe, M., T. Hawighorst, D.G. Jackson, et al. 2001. Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis [see comments]. Nat. Med. 7 : 192 198.
-
(2001)
Nat. Med.
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
-
25
-
-
17744390184
-
Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis
-
Mandriota, S.J., L. Jussila, M. Jeltsch, et al. 2001. Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis. EMBO J. 20 : 672 682.
-
(2001)
EMBO J.
, vol.20
, pp. 672-682
-
-
Mandriota, S.J.1
Jussila, L.2
Jeltsch, M.3
-
26
-
-
0035266283
-
Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth
-
Karpanen, T., M. Egeblad, M.J. Karkkainen, et al. 2001. Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Res. 61 : 1786 1790.
-
(2001)
Cancer Res.
, vol.61
, pp. 1786-1790
-
-
Karpanen, T.1
Egeblad, M.2
Karkkainen, M.J.3
-
27
-
-
0035126049
-
VEGF-D promotes the metastatic spread of tumor cells via the lymphatics [see comments]
-
Stacker, S.A., C. Caesar, M.E. Baldwin, et al. 2001. VEGF-D promotes the metastatic spread of tumor cells via the lymphatics [see comments]. Nat. Med. 7 : 186 191.
-
(2001)
Nat. Med.
, vol.7
, pp. 186-191
-
-
Stacker, S.A.1
Caesar, C.2
Baldwin, M.E.3
-
28
-
-
23044501991
-
Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor
-
Lin, J., A.S. Lalani, T.C. Harding, et al. 2005. Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor. Cancer Res. 65 : 6901 6909.
-
(2005)
Cancer Res.
, vol.65
, pp. 6901-6909
-
-
Lin, J.1
Lalani, A.S.2
Harding, T.C.3
-
29
-
-
0037024472
-
Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling [see comments]
-
He, Y., K. Kozaki, T. Karpanen, et al. 2002. Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling [see comments]. J. Natl. Cancer Inst. 94 : 819 825.
-
(2002)
J. Natl. Cancer Inst.
, vol.94
, pp. 819-825
-
-
He, Y.1
Kozaki, K.2
Karpanen, T.3
-
30
-
-
4243325849
-
Molecular characterization of lymphatic endothelial cells [erratum appears in Proc. Natl. Acad. Sci. USA 2003 Apr 15;100(8):4970
-
Podgrabinska, S., P. Braun, P. Velasco, et al. 2002. Molecular characterization of lymphatic endothelial cells [erratum appears in Proc. Natl. Acad. Sci. USA 2003 Apr 15;100(8):4970]. Proc. Natl. Acad. Sci. USA 99 : 16069 16074.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16069-16074
-
-
Podgrabinska, S.1
Braun, P.2
Velasco, P.3
-
31
-
-
18544386859
-
Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor
-
Petrova, T.V., T. Makinen, T.P. Makela, et al. 2002. Lymphatic endothelial reprogramming of vascular endothelial cells by the Prox-1 homeobox transcription factor. EMBO J. 21 : 4593 4599.
-
(2002)
EMBO J.
, vol.21
, pp. 4593-4599
-
-
Petrova, T.V.1
Makinen, T.2
Makela, T.P.3
-
32
-
-
0035903330
-
Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages [see comments]
-
Kriehuber, E., S. Breiteneder-Geleff, M. Groeger, et al. 2001. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages [see comments]. J. Exp. Med. 194 : 797 808.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 797-808
-
-
Kriehuber, E.1
Breiteneder-Geleff, S.2
Groeger, M.3
-
33
-
-
33745271924
-
In vivo and ex vivo selections using phage-displayed libraries
-
In. T. Clackson. & H.B. Lowman, Eds. Oxford University Press. Oxford, UK.
-
Hoffman, J.A., P. Laakkonen, K. Porkka, et al. 2004. In vivo and ex vivo selections using phage-displayed libraries. In Phage Display. T. Clackson & H.B. Lowman, Eds 171 192. Oxford University Press. Oxford, UK.
-
(2004)
Phage Display.
, pp. 171-192
-
-
Hoffman, J.A.1
Laakkonen, P.2
Porkka, K.3
-
34
-
-
0035375108
-
Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium
-
Prevo, R., S. Banerji, D.J. Ferguson, et al. 2001. Mouse LYVE-1 is an endocytic receptor for hyaluronan in lymphatic endothelium. J. Biol. Chem. 276 : 19420 19430.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19420-19430
-
-
Prevo, R.1
Banerji, S.2
Ferguson, D.J.3
-
35
-
-
0034913816
-
LYVE-1, the lymphatic system and tumor lymphangiogenesis
-
Jackson, D.G., R. Prevo, S. Clasper, et al. 2001. LYVE-1, the lymphatic system and tumor lymphangiogenesis. Trends Immunol. 22 : 317 321.
-
(2001)
Trends Immunol.
, vol.22
, pp. 317-321
-
-
Jackson, D.G.1
Prevo, R.2
Clasper, S.3
-
36
-
-
0032937233
-
Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: Podoplanin as a specific marker for lymphatic endothelium
-
Breiteneder-Geleff, S., A. Soleiman, H. Kowalski, et al. 1999. Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium. Am. J. Pathol. 154 : 385 394.
-
(1999)
Am. J. Pathol.
, vol.154
, pp. 385-394
-
-
Breiteneder-Geleff, S.1
Soleiman, A.2
Kowalski, H.3
-
37
-
-
3042687629
-
Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells
-
Laakkonen, P., M.E. Akerman, H. Biliran, et al. 2004. Antitumor activity of a homing peptide that targets tumor lymphatics and tumor cells. Proc. Natl. Acad. Sci. USA 101 : 9381 9386.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9381-9386
-
-
Laakkonen, P.1
Akerman, M.E.2
Biliran, H.3
-
39
-
-
27744532423
-
Vascular homing peptides with cell-penetrating properties
-
&
-
Ruoslahti, E., T. Duza & L. Zhang. 2005. Vascular homing peptides with cell-penetrating properties. Curr. Pharm. Des. 11 : 3655 3660.
-
(2005)
Curr. Pharm. Des.
, vol.11
, pp. 3655-3660
-
-
Ruoslahti, E.1
Duza, T.2
Zhang, L.3
-
40
-
-
44449161939
-
Selective delivery to vascular addresses: In vivo applications of cell-type-specific cell-penetrating peptides
-
& In. U. Langel, Ed. CRC Press (Taylor & Francis). Boca Raton, FLNew York.
-
Laakkonen, P. & E. Ruoslahti. 2006. Selective delivery to vascular addresses: in vivo applications of cell-type-specific cell-penetrating peptides. In Handbook of Cell-Penetrating Peptides. U. Langel, Ed 413 422. CRC Press (Taylor & Francis). Boca Raton, FL New York.
-
(2006)
Handbook of Cell-Penetrating Peptides.
, pp. 413-422
-
-
Laakkonen, P.1
Ruoslahti, E.2
-
41
-
-
33745257023
-
Lymphatic zip codes in premalignant lesions and tumors [erratum appears in Cancer Res.]
-
Zhang, L., E. Giraudo, J.A. Hoffman, et al. 2006. Lymphatic zip codes in premalignant lesions and tumors [erratum appears in Cancer Res.] Cancer Res. 66 : 5696 5706.
-
(2006)
Cancer Res.
, vol.66
, pp. 5696-5706
-
-
Zhang, L.1
Giraudo, E.2
Hoffman, J.A.3
-
43
-
-
34250869019
-
MDA-MB-435 cells are derived from M14 melanoma cells: A loss for breast cancer, but a boon for melanoma research
-
Rae, J.M.C., C.J. Meck, J.M. Haddad, B.R. Johnson, M.D. 2007. MDA-MB-435 cells are derived from M14 melanoma cells: a loss for breast cancer, but a boon for melanoma research. Breast Cancer Res. Treat. 104 : 13 19.
-
(2007)
Breast Cancer Res. Treat.
, vol.104
, pp. 13-19
-
-
Rae, J.M.C.1
Meck, C.J.2
Haddad, J.M.3
Johnson, B.R.M.D.4
-
44
-
-
12544252451
-
Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties
-
Rae, J.M., S.J. Ramus, M. Waltham, et al. 2004. Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties. Clin. Exp. Met. 21 : 543 552.
-
(2004)
Clin. Exp. Met.
, vol.21
, pp. 543-552
-
-
Rae, J.M.1
Ramus, S.J.2
Waltham, M.3
-
46
-
-
0032819838
-
Anti-cancer activity of targeted pro-apoptotic peptides
-
Ellerby, H.M., W. Arap, L.M. Ellerby, et al. 1999. Anti-cancer activity of targeted pro-apoptotic peptides. Nat. Med. 5 : 1032 1038.
-
(1999)
Nat. Med.
, vol.5
, pp. 1032-1038
-
-
Ellerby, H.M.1
Arap, W.2
Ellerby, L.M.3
-
47
-
-
0035895247
-
A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis
-
&
-
Yi, M. & E. Ruoslahti. 2001. A fibronectin fragment inhibits tumor growth, angiogenesis, and metastasis. Proc. Natl. Acad. Sci. USA 98 : 620 624.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 620-624
-
-
Yi, M.1
Ruoslahti, E.2
-
48
-
-
0029907050
-
A polymeric form of fibronectin has antimetastatic effects against multiple tumor types
-
Pasqualini, R., S. Bourdoulous, E. Koivunen, et al. 1996. A polymeric form of fibronectin has antimetastatic effects against multiple tumor types. Nat. Med. 2 : 1197 1203.
-
(1996)
Nat. Med.
, vol.2
, pp. 1197-1203
-
-
Pasqualini, R.1
Bourdoulous, S.2
Koivunen, E.3
|