Personalized medicine in human space flight: Using Omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance

Metabolomics

Volumn 9, Issue 6, 2013, Pages 1134-1156

  Schmidt, Michael A ^a   Goodwin, Thomas J ^b  

^a Department of Environmental and Radiological Health Sciences   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

Author keywords

Astronaut health; DNA repair; DNA stability; Essential inputs; Exploration; Genomics; Human; Human performance; Metabolomics; Micronutrient; Omics; Oxidative stress; Personalized medicine; Proteomics; Single nucleotide polymorphism; Space flight; Systems biology; Transcriptomics

Indexed keywords

CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DIAZEPAM; ERYTHROMYCIN; LAPATINIB; LIDOCAINE; MEVINOLIN; PARACETAMOL; TRASTUZUMAB; WARFARIN;

CARBON METABOLISM; CHROMOSOMAL INSTABILITY; COSMIC RADIATION; COSMONAUT; DISEASE COURSE; DISEASE SEVERITY; DNA REPAIR; DRUG DISPOSITION; DRUG EFFICACY; DRUG METABOLISM; DRUG TRANSFORMATION; FUNCTIONAL GENOMICS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; HEALTH CARE POLICY; HUMAN; HYPERTENSION; IRON METABOLISM; METABOLOMICS; MICROARRAY ANALYSIS; OXIDATIVE STRESS; PERSONALIZED MEDICINE; PROTEIN EXPRESSION; REVIEW; SPACE FLIGHT; SYSTEMS BIOLOGY;

EID: 84887989953     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-013-0556-3     Document Type: Review

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