메뉴 건너뛰기




Volumn 52, Issue 12, 2011, Pages 9279-9286

Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEINS AND BINDING PROTEINS; FELINE LEUKEMIA VIRUS SUBGROUP C RECEPTOR; MESOPORPHYRIN; MESSENGER RNA; PROTON COUPLED FOLATE TRANSPORTER; UNCLASSIFIED DRUG; ABC TRANSPORTER; BCRP PROTEIN, MOUSE; CARRIER PROTEIN; FLVCR1 PROTEIN, MOUSE; HEME; IRON; METALLOPORPHYRIN; SLC46A1 PROTEIN, MOUSE; VIRUS RECEPTOR; ZINC MESOPORPHYRIN;

EID: 84863697879     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.11-8264     Document Type: Article
Times cited : (25)

References (33)
  • 1
    • 34249740700 scopus 로고    scopus 로고
    • The role of transporters in cellular heme and porphyrin homeostasis
    • Krishnamurthy P, Xie T, Schuetz JD. The role of transporters in cellular heme and porphyrin homeostasis. Pharmacol Ther. 2007; 114:345-358.
    • (2007) Pharmacol Ther , vol.114 , pp. 345-358
    • Krishnamurthy, P.1    Xie, T.2    Schuetz, J.D.3
  • 2
    • 79955663429 scopus 로고    scopus 로고
    • Control of intracellular heme levels: Heme transporters and heme oxygenases
    • Khan AA, Quigley JG. Control of intracellular heme levels: heme transporters and heme oxygenases. Biochim Biophys Acta. 2011; 1813:668-682.
    • (2011) Biochim Biophys Acta , vol.1813 , pp. 668-682
    • Khan, A.A.1    Quigley, J.G.2
  • 3
    • 24144459870 scopus 로고    scopus 로고
    • Identification of an intestinal heme transporter
    • Shayeghi M, Latunde-Dada GO, Oakhill JS, et al. Identification of an intestinal heme transporter. Cell. 2005;122:789-801.
    • (2005) Cell , vol.122 , pp. 789-801
    • Shayeghi, M.1    Latunde-Dada, G.O.2    Oakhill, J.S.3
  • 4
    • 2642526992 scopus 로고    scopus 로고
    • The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme
    • Krishnamurthy P, Ross DD, Nakanishi T, et al. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. J Biol Chem. 2004;279:24218-24225.
    • (2004) J Biol Chem , vol.279 , pp. 24218-24225
    • Krishnamurthy, P.1    Ross, D.D.2    Nakanishi, T.3
  • 5
    • 4544264523 scopus 로고    scopus 로고
    • Identification of a human heme exporter that is essential for erythropoiesis
    • Quigley JG, Yang Z, Worthington MT, et al. Identification of a human heme exporter that is essential for erythropoiesis. Cell. 2004;118:757-766.
    • (2004) Cell , vol.118 , pp. 757-766
    • Quigley, J.G.1    Yang, Z.2    Worthington, M.T.3
  • 6
    • 33751244559 scopus 로고    scopus 로고
    • Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
    • Qiu A, Jansen M, Sakaris A, et al. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell. 2006;127:917-928.
    • (2006) Cell , vol.127 , pp. 917-928
    • Qiu, A.1    Jansen, M.2    Sakaris, A.3
  • 7
    • 38449116048 scopus 로고    scopus 로고
    • Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types
    • Umapathy NS, Gnana-Prakasam JP, Martin PM, et al. Cloning and functional characterization of the proton-coupled electrogenic folate transporter and analysis of its expression in retinal cell types. Invest Ophthalmol Vis Sci. 2007;48:5299-5305.
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 5299-5305
    • Umapathy, N.S.1    Gnana-Prakasam, J.P.2    Martin, P.M.3
  • 8
    • 15244352173 scopus 로고    scopus 로고
    • Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels
    • Zhou S, Zong Y, Ney PA, Nair G, Stewart CF, Sorrentino BP. Increased expression of the Abcg2 transporter during erythroid maturation plays a role in decreasing cellular protoporphyrin IX levels. Blood. 2005;105:2571-2576.
    • (2005) Blood , vol.105 , pp. 2571-2576
    • Zhou, S.1    Zong, Y.2    Ney, P.A.3    Nair, G.4    Stewart, C.F.5    Sorrentino, B.P.6
  • 9
    • 77956547392 scopus 로고    scopus 로고
    • Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin
    • Yang Z, Philips JD, Doty RT, et al. Kinetics and specificity of feline leukemia virus subgroup C receptor (FLVCR) export function and its dependence on hemopexin. J Biol Chem. 2010;285:28874-28882.
    • (2010) J Biol Chem , vol.285 , pp. 28874-28882
    • Yang, Z.1    Philips, J.D.2    Doty, R.T.3
  • 11
    • 70450209180 scopus 로고    scopus 로고
    • Absence of ironregulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: Role of cystine/glutamate exchanger
    • Gnana-Prakasam JP, Thangaraju M, Liu K, et al. Absence of ironregulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchanger. Biochem J. 2009;424:243-252.
    • (2009) Biochem J , vol.424 , pp. 243-252
    • Gnana-Prakasam, J.P.1    Thangaraju, M.2    Liu, K.3
  • 12
    • 79952227908 scopus 로고    scopus 로고
    • Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice
    • Hadziahmetovic M, Song Y, Ponnuru P, et al. Age-dependent retinal iron accumulation and degeneration in hepcidin knockout mice. Invest Ophthalmol Vis Sci. 2011;52:109-118.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 109-118
    • Hadziahmetovic, M.1    Song, Y.2    Ponnuru, P.3
  • 13
    • 84863705651 scopus 로고    scopus 로고
    • Iron-mediated retinal degeneration in hemojuvelin knockout mice
    • Published online September 26
    • Gnana-Prakasam JP, Tawfik A, Romej M, et al. Iron-mediated retinal degeneration in hemojuvelin knockout mice. Biochem J. Published online September 26 2011.
    • (2011) Biochem J.
    • Gnana-Prakasam, J.P.1    Tawfik, A.2    Romej, M.3
  • 16
    • 79957722029 scopus 로고    scopus 로고
    • The blood-retinal barrier: Structure and functional significance
    • Runkle EA, Antonetti DA. The blood-retinal barrier: structure and functional significance. Methods Mol Biol. 2011;686:133-148.
    • (2011) Methods Mol Biol , vol.686 , pp. 133-148
    • Runkle, E.A.1    Antonetti, D.A.2
  • 17
    • 84863681677 scopus 로고    scopus 로고
    • Systemic route for retinal drug delivery: Role of the blood-retinal barrier
    • In: Kompella UB, Edelhauser HF, eds. New York: AAPS Press-Springer
    • Tachikawa M, Ganapathy V, Hosoya K. Systemic route for retinal drug delivery: role of the blood-retinal barrier. In: Kompella UB, Edelhauser HF, eds. Drug Product Development for the Back of the Eye. New York: AAPS Press-Springer; 2011:85-109.
    • (2011) Drug Product Development for the Back of the Eye , pp. 85-109
    • Tachikawa, M.1    Ganapathy, V.2    Hosoya, K.3
  • 18
    • 64049094689 scopus 로고    scopus 로고
    • Synthesis and secretion of hemoglobin by retinal pigment epithelium
    • Tezel TH, Geng L, Lato EB, et al. Synthesis and secretion of hemoglobin by retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2009;50:1911-1919.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 1911-1919
    • Tezel, T.H.1    Geng, L.2    Lato, E.B.3
  • 19
    • 0034617083 scopus 로고    scopus 로고
    • Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium
    • Chancy CD, Kekuda R, Huang W, et al. Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium. J Biol Chem. 2000;275:20676-20684.
    • (2000) J Biol Chem , vol.275 , pp. 20676-20684
    • Chancy, C.D.1    Kekuda, R.2    Huang, W.3
  • 20
    • 77953266081 scopus 로고    scopus 로고
    • Molecular and biochemical characterization of folate transport proteins in retinal Müller cells
    • Bozard BR, Ganapathy PS, Duplantier J, et al. Molecular and biochemical characterization of folate transport proteins in retinal Müller cells. Invest Ophthalmol Vis Sci. 2010;51:3226-3235.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3226-3235
    • Bozard, B.R.1    Ganapathy, P.S.2    Duplantier, J.3
  • 21
    • 0024992158 scopus 로고
    • The growth and behaviour of rat retinal Müller cells in vitro. 1. An improved method for isolation and culture
    • Hicks D, Courtois Y. The growth and behaviour of rat retinal Müller cells in vitro. 1. An improved method for isolation and culture. Exp Eye Res. 1990;51:119-129.
    • (1990) Exp Eye Res , vol.51 , pp. 119-129
    • Hicks, D.1    Courtois, Y.2
  • 22
    • 33644686858 scopus 로고    scopus 로고
    • Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells
    • Umapathy NS, Li W, Mysona BA, Smith SB, Ganapathy V. Expression and function of glutamine transporters SN1 (SNAT3) and SN2 (SNAT5) in retinal Müller cells. Invest Ophthalmol Vis Sci. 2005; 46:3980-3987.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 3980-3987
    • Umapathy, N.S.1    Li, W.2    Mysona, B.A.3    Smith, S.B.4    Ganapathy, V.5
  • 23
    • 0024109174 scopus 로고
    • Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning
    • Barres BA, Silverstein BE, Corey DP, Chun LL. Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. Neuron. 1988;1:791-803.
    • (1988) Neuron , vol.1 , pp. 791-803
    • Barres, B.A.1    Silverstein, B.E.2    Corey, D.P.3    Chun, L.L.4
  • 25
    • 80053301456 scopus 로고    scopus 로고
    • The role of N-methyl-Daspartate receptor activation in homocysteine-induced death of retinal ganglion cells
    • Ganapathy PS, White RE, Ha Y, et al. The role of N-methyl-Daspartate receptor activation in homocysteine-induced death of retinal ganglion cells. Invest Ophthalmol Vis Sci. 2011;52:5515-5524.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 5515-5524
    • Ganapathy, P.S.1    White, R.E.2    Ha, Y.3
  • 26
    • 64849109452 scopus 로고    scopus 로고
    • Expression of the iron-regulatory protein hemojuvelin in retina and its regulation during cytomegalovirus infection
    • Gnana-Prakasam JP, Zhang M, Martin PM, Atherton SS, Smith SB, Ganapathy V. Expression of the iron-regulatory protein hemojuvelin in retina and its regulation during cytomegalovirus infection. Biochem J. 2009;419:533-543.
    • (2009) Biochem J , vol.419 , pp. 533-543
    • Gnana-Prakasam, J.P.1    Zhang, M.2    Martin, P.M.3    Atherton, S.S.4    Smith, S.B.5    Ganapathy, V.6
  • 27
    • 0037377965 scopus 로고    scopus 로고
    • Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells
    • Philp NJ, Wang D, Yoon H, Hjelmeland LM. Polarized expression of monocarboxylate transporters in human retinal pigment epithelium and ARPE-19 cells. Invest Ophthalmol Vis Sci. 2003;44:1716-1721.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 1716-1721
    • Philp, N.J.1    Wang, D.2    Yoon, H.3    Hjelmeland, L.M.4
  • 28
    • 67349274138 scopus 로고    scopus 로고
    • Efflux protein expression in human retinal pigment epithelium cell lines
    • Mannermaa E, Vellonen KS, Ryhanen T, et al. Efflux protein expression in human retinal pigment epithelium cell lines. Pharm Res. 2009;26:1785-1791.
    • (2009) Pharm Res , vol.26 , pp. 1785-1791
    • Mannermaa, E.1    Vellonen, K.S.2    Ryhanen, T.3
  • 29
    • 67649443910 scopus 로고    scopus 로고
    • Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1)
    • Laftah AH, Latunde-Dada GO, Fakih S, Hider RC, Simpson RJ, McKie AT. Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1). Br J Nutr. 2009; 101:1150-1156.
    • (2009) Br J Nutr , vol.101 , pp. 1150-1156
    • Laftah, A.H.1    Latunde-Dada, G.O.2    Fakih, S.3    Hider, R.C.4    Simpson, R.J.5    McKie, A.T.6
  • 30
    • 0030017273 scopus 로고    scopus 로고
    • Hemopexin in the human retina: Protection of the retina against heme-mediated toxicity
    • Hunt RC, Hunt DM, Gaur N, Smith A. Hemopexin in the human retina: protection of the retina against heme-mediated toxicity. J Cell Physiol. 1996;168:71-80.
    • (1996) J Cell Physiol , vol.168 , pp. 71-80
    • Hunt, R.C.1    Hunt, D.M.2    Gaur, N.3    Smith, A.4
  • 31
    • 15944398355 scopus 로고    scopus 로고
    • The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: A novel mechanism of human disease
    • Rother RP, Bell L, Hillmen P, Gladwin MT. The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. JAMA. 2005;293:1653-1662.
    • (2005) JAMA , vol.293 , pp. 1653-1662
    • Rother, R.P.1    Bell, L.2    Hillmen, P.3    Gladwin, M.T.4
  • 33
    • 0025084372 scopus 로고
    • Hematogenous photosensitization: A mechanism for the development of age-related macular degeneration
    • Gottsch JD, Pou S, Bynoe LA, Rosen GM. Hematogenous photosensitization: a mechanism for the development of age-related macular degeneration. Invest Ophthalmol Vis Sci. 1990;31: 1674-1682.
    • (1990) Invest Ophthalmol Vis Sci , vol.31 , pp. 1674-1682
    • Gottsch, J.D.1    Pou, S.2    Bynoe, L.A.3    Rosen, G.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.