Choline deficiency increases lymphocyte apoptosis and DNA damage in humans

American Journal of Clinical Nutrition

Volumn 84, Issue 1, 2006, Pages 88-94

  Da Costa, Kerry Ann ^a   Niculescu, Mihai D ^a   Craciunescu, Corneliu N ^a   Fischer, Leslie M ^a   Zeisel, Steven H ^a  

^a University of North Carolina   (United States)

Author keywords

Apoptosis; Choline deficiency; COMET assay; DNA damage; Humans; Lymphocytes; Single cell gel electrophoresis; Terminal deoxynucleotide transferase mediated dUTP nick end labeling; TUNEL assay

Indexed keywords

CASPASE 3; CHOLINE; FOLIC ACID; BIOLOGICAL MARKER; CASP3 PROTEIN, HUMAN; CASPASE;

ADULT; AGED; APOPTOSIS; ARTICLE; CHOLINE UPTAKE; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; FEMALE; HUMAN; HUMAN EXPERIMENT; LIVER DYSFUNCTION; LYMPHOCYTE COUNT; MALE; MUSCLE DISEASE; NICK END LABELING; NORMAL HUMAN; PERIPHERAL LYMPHOCYTE; VITAMIN DEFICIENCY; ADOLESCENT; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; ENZYMOLOGY; LIVER; LYMPHOCYTE; METABOLISM; MIDDLE AGED; RANDOMIZED CONTROLLED TRIAL; SKELETAL MUSCLE;

RODENTIA;

ADOLESCENT; ADULT; AGED; APOPTOSIS; BIOLOGICAL MARKERS; CASPASE 3; CASPASES; CHOLINE; CHOLINE DEFICIENCY; COMET ASSAY; DNA DAMAGE; FEMALE; FOLIC ACID; HUMANS; IN SITU NICK-END LABELING; LIVER; LYMPHOCYTE COUNT; LYMPHOCYTES; MALE; MIDDLE AGED; MUSCLE, SKELETAL;

EID: 33747381684     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/84.1.88     Document Type: Article

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