Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight

Ophthalmology

Volumn 118, Issue 10, 2011, Pages 2058-2069

  Mader, Thomas H ^a   Gibson, C Robert ^b   Pass, Anastas F ^c   Kramer, Larry A ^d   Lee, Andrew G ^e   Fogarty, Jennifer ^f   Tarver, William J ^f   Dervay, Joseph P ^f   Hamilton, Douglas R ^g   Sargsyan, Ashot ^g   Phillips, John L ^f   Tran, Duc ^b   Lipsky, William ^b   Choi, Jung ^b   Stern, Claudia ^h   Kuyumjian, Raffi ⁱ   Polk, James D ^f  

^a ALASKA NATIVE MEDICAL CENTER   (United States)

^b Coastal Eye Associates ^*  (United States)

^c UNIVERSITY OF HOUSTON   (United States)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^e HOUSTON METHODIST HOSPITAL   (United States)

^f NASA JOHNSON SPACE CENTER   (United States)

^g WYLE LABORATORIES   (United States)

^h GERMAN AEROSPACE CENTER DLR   (Germany)

ⁱ EUROPEAN SPACE AGENCY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHOROID DISEASE; CHOROIDAL FOLD; CLINICAL ARTICLE; COSMONAUT; EYE EDEMA; EYE EXAMINATION; EYE FUNDUS; EYE GLOBE FLATTENING; EYE MALFORMATION; EYE REFRACTION; HUMAN; HYPERMETROPIA; INTRAOCULAR PRESSURE; LUMBAR PUNCTURE; MALE; MEDICAL PHOTOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCUPATIONAL DISEASE; OPTIC DISC EDEMA; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; QUESTIONNAIRE; RETINA EXAMINATION; RETROSPECTIVE STUDY; SPACE FLIGHT; VISION; VISUAL ACUITY; VISUAL IMPAIRMENT;

AEROSPACE MEDICINE; ASTRONAUTS; CHOROID DISEASES; EYE DISEASES; HUMANS; HYPEROPIA; INTRACRANIAL PRESSURE; INTRAOCULAR PRESSURE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PAPILLEDEMA; QUESTIONNAIRES; RETROSPECTIVE STUDIES; SPACE FLIGHT; SPINAL PUNCTURE; TOMOGRAPHY, OPTICAL COHERENCE; VISION DISORDERS; VISUAL ACUITY; WEIGHTLESSNESS;

EID: 80053600623     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2011.06.021     Document Type: Article

References (56)

1. E. Nettleship Peculiar lines in the choroid in a case of post-papillitic atrophy Trans Ophthalmol Soc U K 4 1884 167 168
2. R.E. Kalina, and R.P. Mills Acquired hyperopia with choroidal folds Ophthalmology 87 1980 44 50 (Pubitemid 10196114)
3. J. Lavinsky, D. Lavinsky, F. Lavinsky, and A. Frutuoso Acquired choroidal folds: a sign of idiopathic intracranial hypertension Graefes Arch Clin Exp Ophthalmol 245 2007 883 888 (Pubitemid 46805620)
4. D. Friedman Idiopathic intracranial hypertension Curr Pain Headache Rep 11 2007 62 68 (Pubitemid 46157588)
5. S.R. Griebel, and G.S. Kosmorsky Choroidal folds associated with increased intracranial pressure Am J Ophthalmol 129 2000 513 516 (Pubitemid 30184923)
6. D. Sarraf, and S.D. Schwartz Bilateral choroidal folds and optic neuropathy: a variant of the crowded disk syndrome? Ophthalmology 110 2003 1047 1052 (Pubitemid 36560511)
7. M. Sharma, N.J. Volpe, T. Patel, and A. Kimmel Intracranial hypertension associated with acquired hyperopia and choroidal folds Retina 19 1999 260 262 (Pubitemid 30368150)
8. D.M. Jacobson Intracranial hypertension and the syndrome of acquired hyperopia with choroidal folds J Neuroophthalmol 15 1995 178 185
9. L.M. Cassidy, and M.D. Sanders Choroidal folds and papilloedema Br J Ophthalmol 83 1999 1139 1143 (Pubitemid 29469117)
10. R.A. Dailey, R.P. Mills, and G.K. Stimac The natural history and CT appearance of acquired hyperopia with choroidal folds Ophthalmology 93 1986 1336 1342 (Pubitemid 16009000)
11. D. Liu, and M. Kahn Measurement and relationship of subarachnoid pressure of the optic nerve to intracranial pressures in fresh cadavers Am J Ophthalmol 116 1993 548 556 (Pubitemid 23337039)
12. M.O. Tso, and S.S. Hayreh Optic disc edema in raised intracranial pressure. IV. Axoplasmic transport in experimental papilledema Arch Ophthalmol 95 1977 1458 1462 (Pubitemid 8142315)
13. G. Guiffre, and M.G. Distefano Optical coherence tomography of chorioretinal and choroidal folds Acta Ophthalmol Scand 85 2007 333 336 (Pubitemid 46711373)
14. K. Iwasaki, B.D. Levine, and R. Zhang Human cerebral autoregulation before, during and after spaceflight J Physiol 579 2007 799 810 (Pubitemid 46404360)
15. M.A. Frey, T.H. Mader, and J.P. Bagian Cerebral blood velocity and other cardiovascular responses to 2 days of head-down tilt J Appl Physiol 74 1993 319 325 (Pubitemid 23059763)
16. W.E. Thornton, G.W. Hoffler, and J.A. Rummel Anthropometric changes and fluid shifts R. Johnston, L. Dietlein, Biomedical Results from Skylab 1977 Scientific and Technical Information Office, NASA Washington, DC http://lsda.jsc.nasa.gov/books/skylab//Ch32.htm Accessed May 29, 2011
17. P. Arbeille, G. Fomina, and J. Roumy Adaptation of the left heart, cerebral and femoral arteries, and jugular and femoral veins during short- and long-term head-down tilt and space flights Eur J Appl Physiol 86 2001 157 168
18. B.A. Harris Jr, R.D. Billica, and S.L. Bishop Physical examination during space flight Mayo Clin Proc 72 1997 301 308 (Pubitemid 28194193)
19. S. Herault, G. Fomina, and I. Alferova Cardiac, arterial and venous adaptation to weightlessness during 6-month MIR spaceflights with and without thigh cuffs (bracelets) Eur J Appl Physiol 81 2000 384 390 (Pubitemid 30189961)
20. H. Davson, F.R. Domer, and J.R. Hollingsworth The mechanism of drainage of the cerebrospinal fluid Brain 96 1973 329 336
21. N. Andersson, J. Malm, and A. Eklund Dependency of cerebrospinal fluid outflow resistance on intracranial pressure J Neurosurg 109 2008 918 922
22. N. Alperin, S.H. Lee, and M. Mazda Evidence for the importance of extracranial venous flow in patients with idiopathic intracranial hypertension (IIH) Acta Neurochir Suppl 95 2005 129 132
23. K.G. Kapoor, S.E. Katz, D.M. Grzybowski, and M. Lubow Cerebrospinal fluid outflow: an evolving perspective Brain Res Bull 77 2008 327 334
24. D. Oreskovic, and M. Klarica The formation of cerebrospinal fluid: nearly a hundred years of interpretations and misinterpretations Brain Res Rev 64 2010 241 262
25. V. Giuseffi, M. Wall, P.Z. Siegel, and P.B. Rojas Symptoms and disease associations in idiopathic intracranial hypertension (pseudotumor cerebri): a case-control study Neurology 41 1991 239 244
26. H.E. Killer, G.P. Jaggi, and J. Flammer The optic nerve: a new window into cerebrospinal fluid composition? Brain 129 2006 1027 1030
27. H.E. Killer, G.P. Jaggi, and J. Flammer Cerebrospinal fluid dynamics between the intracranial and the subarachnoid space of the optic nerve Is it always bidirectional? Brain 130 2007 514 520 (Pubitemid 46181104)
28. S.E. Kelman, R.C. Sergott, and G.A. Cioffi Modified optic nerve decompression in patients with functioning lumboperitoneal shunts and progressive visual loss Ophthalmology 98 1991 1449 1453
29. H.E. Killer, G.P. Jaggi, and N.R. Miller Papilledema revisited: is its pathophysiology really understood? Clin Experiment Ophthalmol 37 2009 444 447
30. M. Johnston, A. Zakharov, L. Koh, and D. Armstrong Subarachnoid injection of Microfil reveals connections between cerebrospinal fluid and nasal lymphatics in the non-human primate Neuropathol Appl Neurobiol 31 2005 632 640 (Pubitemid 41668373)
31. J. Draeger, H. Wirt, and R. Schwartz Tonometry under microgravity conditions P.R. Sahm, R. Jansen, M.H. Keller, Proceedings of the Norderney Symposium on Scientific Results of the German Spacelab Mission: D1, Nordenerney, Germany, August 27-29, 1986 1987 Wissenschaftliche Projektfuhrung DI c/o DFVLR Koln, Germany 503 509
32. T.H. Mader, G.R. Taylor, and N. Hunter Intraocular pressure, retinal vascular, and visual acuity changes during 48 hours of 10 degrees head-down tilt Aviat Space Environ Med 61 1990 810 813 (Pubitemid 20295418)
33. C. Chiquet, M.A. Custaud, and A.P. Le Traon Changes in intraocular pressure during prolonged (7-day) head-down tilt bedrest J Glaucoma 12 2003 204 208 (Pubitemid 36736719)
34. N.T. Drozdova, and E.P. Grishin State of the visual analyzer during hypokinesia [in Russian] Kosm Biol Med 6 1972 46 49
35. T.H. Mader, C.R. Gibson, and M. Caputo Intraocular pressure and retinal vascular changes during transient exposure to microgravity Am J Ophthalmol 115 1993 347 350 (Pubitemid 23081076)
36. A.E. Nicogossian, and J.F. Parker Jr Space Physiology and Medicine 1982 NASA, Technical Information Branch Washington, DC 158 NASA SP-447
37. V.P. Costa, and E.S. Arcieri Hypotony maculopathy Acta Ophthalmol Scand 85 2007 586 597 (Pubitemid 47316755)
38. A.C. Westfall, J.D. Ng, J.R. Samples, and J.L. Weissman In reply to: Brodsky MC Flattening of the posterior sclera: hypotony or elevated intracranial pressure [letter]? Am J Ophthalmol 138 2004 511 512 (Pubitemid 39208598)
39. N.T. Drozdova, and O.N. Nesterenko State of the visual analyzer during hypodynamia A.M. Genin, Prolonged Limitation of Motility and its Influence on Human Organism 1970 NASA Washington, DC 192 195 Problems of Space Biology. vol. 13. NASA TT F-639
40. P.J. Mekjavic, O. Eiken, and I.B. Mekjavic Visual function after prolonged bed rest J Gravit Physiol 9 2002 P31 P32
41. T. Grosvenor Reduction in axial length with age: an emmetropizing mechanism for the adult eye? Am J Optom Physiol Opt 64 1987 657 663
42. T.H. Mader, and L.J. White Refractive changes at extreme altitude after radial keratotomy Am J Ophthalmol 119 1995 733 737
43. T.H. Mader, C.L. Blanton, and B.N. Gilbert Refractive changes during 72-hour exposure to altitude after refractive surgery Ophthalmology 103 1996 1188 1195 (Pubitemid 26282499)
44. R.K. Winkle, T.H. Mader, and V.C. Parmley The etiology of refractive changes at high altitude following radial keratotomy: hypoxia versus hypobaria Ophthalmology 105 1998 282 286 (Pubitemid 28090833)
45. D.M. Silver, and O. Geyer Pressure-volume relation for the living human eye Curr Eye Res 20 2000 115 120 (Pubitemid 30099163)
46. H. Kergoat, and J.V. Lovasik Seven-degree head-down tilt reduces choroidal pulsatile ocular blood flow Aviat Space Environ Med 76 2005 930 934 (Pubitemid 41428660)
47. M. Moriyama, K. Ohno-Matsui, and S. Futagami Morphology and long-term changes of choroidal vascular structure in highly myopic eyes with and without posterior staphyloma Ophthalmology 114 2007 1755 1762
48. F.W. Newell Choroidal folds The seventh Harry Searls Gradle Memorial lecture Am J Ophthalmol 75 1973 930 942
49. P. Henkind Radial peripapillary capillaries of the retina. I. Anatomy: human and comparative Br J Ophthalmol 51 1967 115 123
50. M.L. Gomez, F. Mojana, D. Bartsch, and W.R. Freeman Imaging of long-term retinal damage after resolved cotton wool spots Ophthalmology 116 2009 2407 2414
51. D. Schmidt The mystery of cotton-wool spots: a review of recent and historical descriptions Eur J Med Res 13 2008 231 266 (Pubitemid 351998232)
52. UK Prospective Diabetes Study (UKPDS) Group Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus: UKPDS 69 Arch Ophthalmol 122 2004 1631 1640
53. M.M. Berrey, T. Shea, and L. Corey Cotton-wool spots in primary HIV infection [letter] J Acquir Immune Defic Syndr Hum Retrovirol 19 1998 197 198 (Pubitemid 28460697)
54. A. Agrawal, and M. McKibbin Purtscher's retinopathy: epidemiology, clinical features and outcome Br J Ophthalmol 91 2007 1456 1459 (Pubitemid 350044045)
55. D.S. Morris, J. Somner, and M.J. Donald The eye at altitude Adv Exp Med Biol 588 2006 249 270
56. T.Y. Wong, and R. McIntosh Hypertensive retinopathy signs as risk indicators of cardiovascular morbidity and mortality Br Med Bull 7374 2005 57 70 (Pubitemid 43020358)