-
1
-
-
84891828861
-
Intestinal fluid and electrolyte movement
-
Philadelphia: Saunders Elsevier Boron WF, Boulaep EL 2
-
Intestinal fluid and electrolyte movement. Binder HJ, Medical physiology: a cellular and molecular approach boron Philadelphia: Saunders Elsevier, Boron WF, Boulaep EL, 2 2012 933 948
-
(2012)
Medical Physiology: A Cellular and Molecular Approach Boron
, pp. 933-948
-
-
Binder, H.J.1
-
2
-
-
75749146169
-
Coexistence of quiescent and active adult stem cells in mammals
-
10.1126/science.1180794 20110496
-
Coexistence of quiescent and active adult stem cells in mammals. Li L, Clevers H, Science 2010 327 542 545 10.1126/science.1180794 20110496
-
(2010)
Science
, vol.327
, pp. 542-545
-
-
Li, L.1
Clevers, H.2
-
3
-
-
44349126693
-
Colonic crypt organization and tumorigenesis
-
10.1038/nrc2392
-
Colonic crypt organization and tumorigenesis. Humphries A, Wright NA, Nature Rev Cancer 2008 8 415 424 10.1038/nrc2392
-
(2008)
Nature Rev Cancer
, vol.8
, pp. 415-424
-
-
Humphries, A.1
Wright, N.A.2
-
4
-
-
84880548336
-
The intestinal crypt, a prototype stem cell compartment
-
10.1016/j.cell.2013.07.004 23870119
-
The intestinal crypt, a prototype stem cell compartment. Clevers H, Cell 2013 154 274 284 10.1016/j.cell.2013.07.004 23870119
-
(2013)
Cell
, vol.154
, pp. 274-284
-
-
Clevers, H.1
-
5
-
-
0035577284
-
Computer modeling implicates stem cell overproduction in colon cancer initiation
-
11731419
-
Computer modeling implicates stem cell overproduction in colon cancer initiation. Boman BM, Fields JZ, Bonham-Carter O, Runquist OA, Cancer Res 2001 61 8408 8411 11731419
-
(2001)
Cancer Res
, vol.61
, pp. 8408-8411
-
-
Boman, B.M.1
Fields, J.Z.2
Bonham-Carter, O.3
Runquist, O.A.4
-
6
-
-
34247267072
-
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer
-
10.1073/pnas.0611179104 17360468
-
Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer. Johnston MD, Edwards CM, Bodmer WF, Maini PK, Chapman SJ, Proc Natl Acad Sci USA 2007 104 4008 4013 10.1073/pnas.0611179104 17360468
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 4008-4013
-
-
Johnston, M.D.1
Edwards, C.M.2
Bodmer, W.F.3
Maini, P.K.4
Chapman, S.J.5
-
7
-
-
0031557884
-
Clonality and life cycles of intestinal crypts explained by a state dependent stochastic model of epithelial stem cell organization
-
10.1006/jtbi.1996.0340
-
Clonality and life cycles of intestinal crypts explained by a state dependent stochastic model of epithelial stem cell organization. Loeffler M, Bratke T, Paulus U, Li YQ, Potten CS, J Thoret Biol 1997 186 41 54 10.1006/jtbi.1996.0340
-
(1997)
J Thoret Biol
, vol.186
, pp. 41-54
-
-
Loeffler, M.1
Bratke, T.2
Paulus, U.3
Li, Y.Q.4
Potten, C.S.5
-
8
-
-
79551565619
-
A comprehensive model of the spatio-termporal stem cell and tissue organization in the intestinal crypt
-
A comprehensive model of the spatio-termporal stem cell and tissue organization in the intestinal crypt. Buske P, Galle J, Barker N, Aust G, Clevers H, Loeffler M, PLoS Comp Biol 2011 7 31001045
-
(2011)
PLoS Comp Biol
, vol.7
, pp. 31001045
-
-
Buske, P.1
Galle, J.2
Barker, N.3
Aust, G.4
Clevers, H.5
Loeffler, M.6
-
10
-
-
0025641727
-
Stem cells: Attributes, cycles, spirals, pitfalls, and uncertainties. Lessons from and from the crypt
-
Stem cells: attributes, cycles, spirals, pitfalls, and uncertainties. Lessons from and from the crypt. Potten CS, Loeffler M, Dev 1990 110 1001 1020
-
(1990)
Dev
, vol.110
, pp. 1001-1020
-
-
Potten, C.S.1
Loeffler, M.2
-
11
-
-
33646045010
-
Stem cells and cancer: Two faces of eve
-
10.1016/j.cell.2006.03.011 16564000
-
Stem cells and cancer: two faces of eve. Clark MF, Fuller M, Cell 2006 124 1111 1115 10.1016/j.cell.2006.03.011 16564000
-
(2006)
Cell
, vol.124
, pp. 1111-1115
-
-
Clark, M.F.1
Fuller, M.2
-
12
-
-
0034712109
-
Out of Eden: Stem cells and their niches
-
10.1126/science.287.5457.1427 10688781
-
Out of Eden: stem cells and their niches. Watt FM, Hogan B, Science 2000 287 1427 1430 10.1126/science.287.5457.1427 10688781
-
(2000)
Science
, vol.287
, pp. 1427-1430
-
-
Watt, F.M.1
Hogan, B.2
-
13
-
-
0035499450
-
Stem cells find their niche
-
10.1038/35102160 11689954
-
Stem cells find their niche. Spradling A, Drummond-Barbosa D, Kai T, Nature 2001 414 98 104 10.1038/35102160 11689954
-
(2001)
Nature
, vol.414
, pp. 98-104
-
-
Spradling, A.1
Drummond-Barbosa, D.2
Kai, T.3
-
14
-
-
1642603951
-
Socializing with the neighbors: Stem cells and their niche
-
10.1016/S0092-8674(04)00255-7 15035980
-
Socializing with the neighbors: stem cells and their niche. Fuchs E, Tumbar T, Guasch G, Cell 2004 116 769 778 10.1016/S0092-8674(04)00255-7 15035980
-
(2004)
Cell
, vol.116
, pp. 769-778
-
-
Fuchs, E.1
Tumbar, T.2
Guasch, G.3
-
15
-
-
33646428091
-
Normal stem cells and cancer stem cells: The niche matters
-
10.1158/0008-5472.CAN-05-3986 16651403
-
Normal stem cells and cancer stem cells: the niche matters. Li L, Neaves WB, Cancer Res 2006 66 4553 4557 10.1158/0008-5472.CAN-05-3986 16651403
-
(2006)
Cancer Res
, vol.66
, pp. 4553-4557
-
-
Li, L.1
Neaves, W.B.2
-
16
-
-
34547180739
-
The gastrointestinal tract stem cell niche
-
10.1007/s12015-006-0048-1 17625256
-
The gastrointestinal tract stem cell niche. Yen T-H, Wright NA, Stem Cell Rev 2006 2 203 212 10.1007/s12015-006-0048-1 17625256
-
(2006)
Stem Cell Rev
, vol.2
, pp. 203-212
-
-
Yen, T.-H.1
Wright, N.A.2
-
17
-
-
39149144034
-
Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life
-
Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Morrison SJ, Spradling AC, Cell 2008 32 598 611
-
(2008)
Cell
, vol.32
, pp. 598-611
-
-
Morrison, S.J.1
Spradling, A.C.2
-
18
-
-
79959238013
-
Microenvironment regulation of stem cells in intestinal homeostasis and cancer
-
10.1038/nature10212 21677748
-
Microenvironment regulation of stem cells in intestinal homeostasis and cancer. Medema JP, Vermeulen L, Nature 2011 474 318 326 10.1038/nature10212 21677748
-
(2011)
Nature
, vol.474
, pp. 318-326
-
-
Medema, J.P.1
Vermeulen, L.2
-
19
-
-
84857985977
-
What does the concept of the stem cell niche really mean today?
-
10.1186/1741-7007-10-19 22405133
-
What does the concept of the stem cell niche really mean today? Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T, BMC Biol 2012 10 19 34 10.1186/1741-7007-10-19 22405133
-
(2012)
BMC Biol
, vol.10
, pp. 19-34
-
-
Lander, A.D.1
Kimble, J.2
Clevers, H.3
Fuchs, E.4
Montarras, D.5
Buckingham, M.6
Calof, A.L.7
Trumpp, A.8
Oskarsson, T.9
-
20
-
-
12644269195
-
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action
-
10.1073/pnas.94.13.6770 9192640
-
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin JS, Proc Natl Acad Sci USA 1997 94 6770 6775 10.1073/pnas.94.13.6770 9192640
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6770-6775
-
-
Finch, P.W.1
He, X.2
Kelley, M.J.3
Uren, A.4
Schaudies, R.P.5
Popescu, N.C.6
Rudikoff, S.7
Aaronson, S.A.8
Varmus, H.E.9
Rubin, J.S.10
-
21
-
-
79956351015
-
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
-
10.1073/pnas.1102454108 21498687
-
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Chaffer CL, Brueckmann I, Scheel C, Kaestli A, Wiggins PA, Rodigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA, Proc Natl Acad Sci USA 2011 108 7950 7955 10.1073/pnas.1102454108 21498687
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 7950-7955
-
-
Chaffer, C.L.1
Brueckmann, I.2
Scheel, C.3
Kaestli, A.4
Wiggins, P.A.5
Rodigues, L.O.6
Brooks, M.7
Reinhardt, F.8
Su, Y.9
Polyak, K.10
Arendt, L.M.11
Kuperwasser, C.12
Bierie, B.13
Weinberg, R.A.14
-
22
-
-
0346458662
-
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
-
10.1073/pnas.2536800100 14695885
-
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Kuhnert F, Davis CR, Wang H-T, Chu P, Lee M, Yuan J, Nusse R, Kuo CJ, Proc Natl Acad Sci USA 2004 101 266 271 10.1073/pnas.2536800100 14695885
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 266-271
-
-
Kuhnert, F.1
Davis, C.R.2
Wang, H.-T.3
Chu, P.4
Lee, M.5
Yuan, J.6
Nusse, R.7
Kuo, C.J.8
-
23
-
-
78651067425
-
Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells
-
10.1073/pnas.1013004108 21173232
-
Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells. Montgomery RK, Carlone DL, Richmond C, Farilla L, Kranendonk MEG, Henderson DE, Baffour-Awuah NY, Ambruzs DM, Fogli LK, Algra S, Breault DT, Proc Natl Acad Sci USA 2011 108 179 184 10.1073/pnas.1013004108 21173232
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 179-184
-
-
Montgomery, R.K.1
Carlone, D.L.2
Richmond, C.3
Farilla, L.4
Kranendonk, M.E.G.5
Henderson, D.E.6
Baffour-Awuah, N.Y.7
Ambruzs, D.M.8
Fogli, L.K.9
Algra, S.10
Breault, D.T.11
-
24
-
-
78751644734
-
Patheth cells constitute the niche for Lgr5 stem cells in intestinal crypts
-
10.1038/nature09637 21113151
-
Patheth cells constitute the niche for Lgr5 stem cells in intestinal crypts. Sato T, van Es JH, Snippert HJ, Stange DE, Vries RG, van den Born M, Barker N, Shroyer NF, van de Wetering M, Clevers H, Nature 2011 469 415 418 10.1038/nature09637 21113151
-
(2011)
Nature
, vol.469
, pp. 415-418
-
-
Sato, T.1
Van Es, J.H.2
Snippert, H.J.3
Stange, D.E.4
Vries, R.G.5
Van Den Born, M.6
Barker, N.7
Shroyer, N.F.8
Van De Wetering, M.9
Clevers, H.10
-
25
-
-
83255193921
-
Interconversion between intestinal stem cell populations in distinct niches
-
10.1126/science.1213214 22075725
-
Interconversion between intestinal stem cell populations in distinct niches. Takeda N, Jain R, LeBoeuf MR, Wang Q, Lu MM, Epstein JA, Science 2011 334 1420 1424 10.1126/science.1213214 22075725
-
(2011)
Science
, vol.334
, pp. 1420-1424
-
-
Takeda, N.1
Jain, R.2
Leboeuf, M.R.3
Wang, Q.4
Lu, M.M.5
Epstein, J.A.6
-
26
-
-
80054041585
-
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable
-
10.1038/nature10408 21927002
-
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Tian H, Biehs B, Warming S, Leong KG, Rangell L, Klien OD, de Sauvage FJ, Nature 2011 478 255 259 10.1038/nature10408 21927002
-
(2011)
Nature
, vol.478
, pp. 255-259
-
-
Tian, H.1
Biehs, B.2
Warming, S.3
Leong, K.G.4
Rangell, L.5
Klien, O.D.6
De Sauvage, F.J.7
-
27
-
-
84867097416
-
DII1+ secretory progenitor cells revert to stem cells upon crypt damage
-
10.1038/ncb2581 23000963
-
DII1+ secretory progenitor cells revert to stem cells upon crypt damage. van Es JH, Sato T, van de Wetering M, Lyubimova A, Nee AN, Gregorieff A, Sasaki N, Zeinstra L, van den Born M, Korving J, Martens AC, Barker N, van Oudenaarden A, Clevers H, Nat Cell Biol 2012 14 1099 1104 10.1038/ncb2581 23000963
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1099-1104
-
-
Van Es, J.H.1
Sato, T.2
Van De Wetering, M.3
Lyubimova, A.4
Nee, A.N.5
Gregorieff, A.6
Sasaki, N.7
Zeinstra, L.8
Van Den Born, M.9
Korving, J.10
Martens, A.C.11
Barker, N.12
Van Oudenaarden, A.13
Clevers, H.14
-
28
-
-
0036098242
-
Tissue stem cells: Definition, plasticity, heterogeneity, self-organization and models - A conceptual approach
-
10.1159/000057688 12021488
-
Tissue stem cells: definition, plasticity, heterogeneity, self-organization and models-A conceptual approach. Loeffler M, Roeder I, Cells Tissues Organs 2002 171 8 26 10.1159/000057688 12021488
-
(2002)
Cells Tissues Organs
, vol.171
, pp. 8-26
-
-
Loeffler, M.1
Roeder, I.2
-
29
-
-
34848885826
-
Sic transit Gloria: Farewell to the epidermal transit amplifying cell?
-
Sic transit Gloria: farewell to the epidermal transit amplifying cell? Jones PH, Simons BD, Watt FM, Cell Stem Cell 2007 1 1 11
-
(2007)
Cell Stem Cell
, vol.1
, pp. 1-11
-
-
Jones, P.H.1
Simons, B.D.2
Watt, F.M.3
-
30
-
-
84867342942
-
Identifying the stem cell of the intestinal crypt: Strategies and pitfalls
-
10.1016/j.stem.2012.09.009 23040474
-
Identifying the stem cell of the intestinal crypt: strategies and pitfalls. Barker N, van Oudenaarden A, Clevers H, Cell Stem Cell 2012 11 452 460 10.1016/j.stem.2012.09.009 23040474
-
(2012)
Cell Stem Cell
, vol.11
, pp. 452-460
-
-
Barker, N.1
Van Oudenaarden, A.2
Clevers, H.3
-
31
-
-
84872008395
-
Cell plasticity and heterogeneity in cancer
-
10.1373/clinchem.2012.184655 23220226
-
Cell plasticity and heterogeneity in cancer. Marjanovic ND, Weinberg RA, Chaffer CL, Clin Chem 2013 59 168 179 10.1373/clinchem.2012.184655 23220226
-
(2013)
Clin Chem
, vol.59
, pp. 168-179
-
-
Marjanovic, N.D.1
Weinberg, R.A.2
Chaffer, C.L.3
-
32
-
-
58849094974
-
Cell lineages and the logic of prolifeative control
-
Cell lineages and the logic of prolifeative control. Lander AD, Gokoffski KK, Wan FYM, Nie Q, Calof AL, PLoS Biol 2009 7 1000015
-
(2009)
PLoS Biol
, vol.7
, pp. 51000015
-
-
Lander, A.D.1
Gokoffski, K.K.2
Wan, F.Y.M.3
Nie, Q.4
Calof, A.L.5
-
33
-
-
84862106483
-
Modelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal crypt
-
Modelling the spatio-temporal cell dynamics reveals novel insights on cell differentiation and proliferation in the small intestinal crypt. Pin C, Watson AJM, Carding SR, PLoS ONE 2012 7 337115
-
(2012)
PLoS ONE
, vol.7
, pp. 337115
-
-
Pin, C.1
Watson, A.J.M.2
Carding, S.R.3
-
34
-
-
84990553606
-
Intestinal cell proliferation. I. A comprehensive model of steady-state proliferation in the crypt
-
3802185
-
Intestinal cell proliferation. I. A comprehensive model of steady-state proliferation in the crypt. Loeffler M, Stein R, Wichmann HE, Potten CS, Kaur P, Chwalinski S, Cell Tissue Kinet 1986 19 627 645 3802185
-
(1986)
Cell Tissue Kinet
, vol.19
, pp. 627-645
-
-
Loeffler, M.1
Stein, R.2
Wichmann, H.E.3
Potten, C.S.4
Kaur, P.5
Chwalinski, S.6
-
35
-
-
44849111911
-
How dysregulated colonic crypt dynamics cause stem cell overpopulation and initiate colon cancer
-
10.1158/0008-5472.CAN-07-2061 18451157
-
How dysregulated colonic crypt dynamics cause stem cell overpopulation and initiate colon cancer. Boman BM, Fields JZ, Cavanaugh KL, Guetter A, Runquist OA, Cancer Res 2008 68 3304 3313 10.1158/0008-5472.CAN-07-2061 18451157
-
(2008)
Cancer Res
, vol.68
, pp. 3304-3313
-
-
Boman, B.M.1
Fields, J.Z.2
Cavanaugh, K.L.3
Guetter, A.4
Runquist, O.A.5
-
36
-
-
33744979495
-
Crypt dynamics and colorectal cancer: Advances in mathematical modeling
-
10.1111/j.1365-2184.2006.00378.x 16671995
-
Crypt dynamics and colorectal cancer: advances in mathematical modeling. van Leeuwen IMM, Byrne HM, Jensen OE, King JR, Cell Prolif 2006 39 157 181 10.1111/j.1365-2184.2006.00378.x 16671995
-
(2006)
Cell Prolif
, vol.39
, pp. 157-181
-
-
Van Leeuwen, I.M.M.1
Byrne, H.M.2
Jensen, O.E.3
King, J.R.4
-
37
-
-
33646182727
-
Organizing cell renewal in the intestine: Stem cells, signals and combinatorial control
-
10.1038/nrg1840
-
Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Crosnier C, Stamataki D, Lewis J, Nat Rev Genetics 2006 7 349 359 10.1038/nrg1840
-
(2006)
Nat Rev Genetics
, vol.7
, pp. 349-359
-
-
Crosnier, C.1
Stamataki, D.2
Lewis, J.3
-
38
-
-
23244448347
-
Expression pattern of Wnt signaling components in the adult intestine
-
Expression pattern of Wnt signaling components in the adult intestine. Gregorieff A, Pinto D, Begthel H, Destree O, Kielman M, Clevers H, Gastroenterol 2005 129 626 638
-
(2005)
Gastroenterol
, vol.129
, pp. 626-638
-
-
Gregorieff, A.1
Pinto, D.2
Begthel, H.3
Destree, O.4
Kielman, M.5
Clevers, H.6
-
39
-
-
34848868159
-
Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors
-
10.1073/pnas.0707210104 17881565
-
Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors. Kosinski C, Li VSW, Chan ASY, Zhang J, Tsui CHWY, Chan TL, Mifflin RC, Powell DW, Yuen ST, Leung SY, Chen X, Proc Natl Acad Sci USA 2007 104 15418 15423 10.1073/pnas.0707210104 17881565
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 15418-15423
-
-
Kosinski, C.1
Li, V.S.W.2
Chan, A.S.Y.3
Zhang, J.4
Tsui, C.5
Chan, T.L.6
Mifflin, R.C.7
Powell, D.W.8
Yuen, S.T.9
Leung, S.Y.10
Chen, X.11
-
40
-
-
83255177150
-
Single-cell dissection of transcriptional heterogeneity in human colon tumors
-
10.1038/nbt.2038
-
Single-cell dissection of transcriptional heterogeneity in human colon tumors. Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, Leyrat AA, Sim S, Okamoto J, Johnston DM, Qian D, Zabala M, Bueno J, Neff NF, Wang J, Shelton AS, Visser B, Hisamori S, Shimono Y, van de Wetering M, Clevers H, Clarke MF, Quake SR, Nat Biotech 2011 29 1120 1127 10.1038/nbt.2038
-
(2011)
Nat Biotech
, vol.29
, pp. 1120-1127
-
-
Dalerba, P.1
Kalisky, T.2
Sahoo, D.3
Rajendran, P.S.4
Rothenberg, M.E.5
Leyrat, A.A.6
Sim, S.7
Okamoto, J.8
Johnston, D.M.9
Qian, D.10
Zabala, M.11
Bueno, J.12
Neff, N.F.13
Wang, J.14
Shelton, A.S.15
Visser, B.16
Hisamori, S.17
Shimono, Y.18
Van De Wetering, M.19
Clevers, H.20
Clarke, M.F.21
Quake, S.R.22
more..
-
41
-
-
84861986053
-
Wnt/-catenin signaling and disease
-
10.1016/j.cell.2012.05.012 22682243
-
Wnt/-catenin signaling and disease. Clevers H, Nusse R, Cell 2012 149 1192 1205 10.1016/j.cell.2012.05.012 22682243
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
42
-
-
0023894101
-
A clonal marker induced by mutation in mouse intestinal epithelium
-
10.1038/333463a0 3163778
-
A clonal marker induced by mutation in mouse intestinal epithelium. Winton DJ, Blount MA, Ponder BA, Nature 1988 333 463 466 10.1038/333463a0 3163778
-
(1988)
Nature
, vol.333
, pp. 463-466
-
-
Winton, D.J.1
Blount, M.A.2
Ponder, B.A.3
-
43
-
-
0038079684
-
Bottom-up histogenesis of colorectal adenomas: Origin in the monocryptal adenoma and initial expansion by crypt fission
-
12839979
-
Bottom-up histogenesis of colorectal adenomas: origin in the monocryptal adenoma and initial expansion by crypt fission. Preston SL, Wong W-M, Chan AO-O, Poulson R, Jeffery R, Goodlad RA, Mandir N, Elia G, Novelli M, Bodmer WF, Tomlinson IP, Wright NA, Cancer Res 2003 63 3819 3825 12839979
-
(2003)
Cancer Res
, vol.63
, pp. 3819-3825
-
-
Preston, S.L.1
Wong, W.-M.2
Chan, A.-O.3
Poulson, R.4
Jeffery, R.5
Goodlad, R.A.6
Mandir, N.7
Elia, G.8
Novelli, M.9
Bodmer, W.F.10
Tomlinson, I.P.11
Wright, N.A.12
-
44
-
-
79551591946
-
Tracing adult stem cells
-
10.1038/embor.2010.216 21252944
-
Tracing adult stem cells. Snippert HJ, Clevers H, EMBO Rep 2011 12 113 121 10.1038/embor.2010.216 21252944
-
(2011)
EMBO Rep
, vol.12
, pp. 113-121
-
-
Snippert, H.J.1
Clevers, H.2
-
45
-
-
84875460038
-
Tracking cells in their native habitat: Lineage tracing in epithelial neoplasia
-
10.1038/nrc3460 23388619
-
Tracking cells in their native habitat: lineage tracing in epithelial neoplasia. Alcolea MP, Jones PH, Nat Rev Cancer 2013 13 161 171 10.1038/nrc3460 23388619
-
(2013)
Nat Rev Cancer
, vol.13
, pp. 161-171
-
-
Alcolea, M.P.1
Jones, P.H.2
-
46
-
-
77957223906
-
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
-
10.1016/j.cell.2010.09.016 20887898
-
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Snippert HJ, van der Flier LG, Sato T, van Es JH, van den Born M, Kroon-Veenboer C, Barker N, Klein AM, van Rheenen J, Simons BD, Clevers H, Cell 2010 143 134 144 10.1016/j.cell.2010.09.016 20887898
-
(2010)
Cell
, vol.143
, pp. 134-144
-
-
Snippert, H.J.1
Van Der Flier, L.G.2
Sato, T.3
Van Es, J.H.4
Van Den Born, M.5
Kroon-Veenboer, C.6
Barker, N.7
Klein, A.M.8
Van Rheenen, J.9
Simons, B.D.10
Clevers, H.11
-
47
-
-
77958485383
-
Intestinal stem cell replacement follows a pattern of neutral drift
-
10.1126/science.1196236 20929733
-
Intestinal stem cell replacement follows a pattern of neutral drift. Lopez-Garcia C, Klein AM, Simons BD, Winton DJ, Science 2010 330 822 825 10.1126/science.1196236 20929733
-
(2010)
Science
, vol.330
, pp. 822-825
-
-
Lopez-Garcia, C.1
Klein, A.M.2
Simons, B.D.3
Winton, D.J.4
-
48
-
-
80455174708
-
Stem cell self-renewal in intestinal crypt
-
10.1016/j.yexcr.2011.07.010
-
Stem cell self-renewal in intestinal crypt. Simons BD, Clevers H, Expt Cell Res 2011 317 2719 2724 10.1016/j.yexcr.2011.07.010
-
(2011)
Expt Cell Res
, vol.317
, pp. 2719-2724
-
-
Simons, B.D.1
Clevers, H.2
-
49
-
-
0027318112
-
Somatic mutation, monoclonality and stochastic models of stem cell organization in the intestinal crypt
-
10.1006/jtbi.1993.1031
-
Somatic mutation, monoclonality and stochastic models of stem cell organization in the intestinal crypt. Loeffler M, Birke A, Winton D, Potten C, J Theoret Biol 1993 160 471 491 10.1006/jtbi.1993.1031
-
(1993)
J Theoret Biol
, vol.160
, pp. 471-491
-
-
Loeffler, M.1
Birke, A.2
Winton, D.3
Potten, C.4
-
50
-
-
84856427171
-
Mathematical modeling of monoclonal conversion in the colonic crypt
-
Mathematical modeling of monoclonal conversion in the colonic crypt. Fletcher AG, Breward CJW, Chapman SJ, J Theoret Biol 2012 300 118 133
-
(2012)
J Theoret Biol
, vol.300
, pp. 118-133
-
-
Fletcher, A.G.1
Breward, C.J.W.2
Chapman, S.J.3
-
51
-
-
79751489596
-
Molecular genetics of colorectal cancer
-
10.1146/annurev-pathol-011110-130235
-
Molecular genetics of colorectal cancer. Fearon ER, Annu Rev Pathol Mech 2011 6 479 507 10.1146/annurev-pathol-011110-130235
-
(2011)
Annu Rev Pathol Mech
, vol.6
, pp. 479-507
-
-
Fearon, E.R.1
-
52
-
-
0036849561
-
Migrating colonic crypt epithelial cells: Primary targets for transformation
-
10.1093/carcin/23.11.1777 12419824
-
Migrating colonic crypt epithelial cells: primary targets for transformation. Lamprecht SA, Lipkin M, Carcinogenesis 2002 23 1777 1780 10.1093/carcin/23.11.1777 12419824
-
(2002)
Carcinogenesis
, vol.23
, pp. 1777-1780
-
-
Lamprecht, S.A.1
Lipkin, M.2
-
53
-
-
33846043179
-
Review article: Is there a common principle in the development of garstrointestinal cancers? Stem cells in the origin of cancer
-
Review article: is there a common principle in the development of garstrointestinal cancers? Stem cells in the origin of cancer. Wright NA, Aliment Pharmacol Ther 2006 24 Suppl 4 34 40
-
(2006)
Aliment Pharmacol Ther
, vol.24
, Issue.SUPPL. 4
, pp. 34-40
-
-
Wright, N.A.1
-
54
-
-
0035956913
-
Top-down morphogenesis of colorectal tumors
-
10.1073/pnas.051629398 11226292
-
Top-down morphogenesis of colorectal tumors. Shih I-M, Wang T-L, Traverso G, Romans K, Hamilton SR, Ben-Sasson S, Kinzler KW, Vogelstein B, Proc Natl Acad Sci USA 2001 98 2640 2645 10.1073/pnas.051629398 11226292
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 2640-2645
-
-
Shih, I.-M.1
Wang, T.-L.2
Traverso, G.3
Romans, K.4
Hamilton, S.R.5
Ben-Sasson, S.6
Kinzler, K.W.7
Vogelstein, B.8
-
55
-
-
59049087696
-
Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation
-
10.1038/nature07589 19092805
-
Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation. Zhu L, Gibson P, Currie DS, Tong Y, Richardson RJ, Bayazitov IT, Poppleton H, Zakharenko S, Ellison DW, Gibertson RJ, Nature 2009 457 603 607 10.1038/nature07589 19092805
-
(2009)
Nature
, vol.457
, pp. 603-607
-
-
Zhu, L.1
Gibson, P.2
Currie, D.S.3
Tong, Y.4
Richardson, R.J.5
Bayazitov, I.T.6
Poppleton, H.7
Zakharenko, S.8
Ellison, D.W.9
Gibertson, R.J.10
-
56
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
10.1038/nature07602 19092804
-
Crypt stem cells as the cells-of-origin of intestinal cancer. Barker N, Ridgeway RA, van Es JH, van de Wetering M, Begthel H, van den Born M, Danenberg E, Clarke AR, Sansom OJ, Clevers H, Nature 2009 457 608 611 10.1038/nature07602 19092804
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgeway, R.A.2
Van Es, J.H.3
Van De Wetering, M.4
Begthel, H.5
Van Den Born, M.6
Danenberg, E.7
Clarke, A.R.8
Sansom, O.J.9
Clevers, H.10
-
57
-
-
17144366931
-
Initiation of colorectal cancer: Where do the two hits hit?
-
10.4161/cc.3.12.1186 15611641
-
Initiation of colorectal cancer: where do the two hits hit? Komarova NL, Wang L, Cell Cycle 2004 3 1558 1565 10.4161/cc.3.12.1186 15611641
-
(2004)
Cell Cycle
, vol.3
, pp. 1558-1565
-
-
Komarova, N.L.1
Wang, L.2
-
58
-
-
33644501491
-
Epithelial tissue architecture protects against cancer
-
10.1016/j.mbs.2005.12.001 16427657
-
Epithelial tissue architecture protects against cancer. Komarova NL, Cheng P, Math Biosci 2006 200 90 117 10.1016/j.mbs.2005.12.001 16427657
-
(2006)
Math Biosci
, vol.200
, pp. 90-117
-
-
Komarova, N.L.1
Cheng, P.2
-
59
-
-
84865293885
-
A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt
-
A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt. Mirams GR, Fletcher AG, Maini PK, Byrne HM, J Theoret Biol 2012 312 143 156
-
(2012)
J Theoret Biol
, vol.312
, pp. 143-156
-
-
Mirams, G.R.1
Fletcher, A.G.2
Maini, P.K.3
Byrne, H.M.4
-
60
-
-
0025224214
-
A comprehensive study of the radiobiological response of the murine (BDF1) small intestine
-
10.1080/09553009014552281 1978853
-
A comprehensive study of the radiobiological response of the murine (BDF1) small intestine. Potten CS, Int J Radiat Biol 1990 58 925 973 10.1080/09553009014552281 1978853
-
(1990)
Int J Radiat Biol
, vol.58
, pp. 925-973
-
-
Potten, C.S.1
-
61
-
-
0019975121
-
The kinetics of villus cell populations in the mouse small intestine. II. Studies on growth control after death of proliferative cells induced by cytosine arabinoside, with special reference to negative feedback mechanisms
-
7172198
-
The kinetics of villus cell populations in the mouse small intestine. II. Studies on growth control after death of proliferative cells induced by cytosine arabinoside, with special reference to negative feedback mechanisms. Wright NA, Al-Nafussi A, Cell Tissue Kinet 1982 15 611 631 7172198
-
(1982)
Cell Tissue Kinet
, vol.15
, pp. 611-631
-
-
Wright, N.A.1
Al-Nafussi, A.2
-
62
-
-
0023808381
-
The doubling time of regenerating clonogenic cells in the crypts of irradiated mouse small intestine
-
10.1080/09553008814552421 2903885
-
The doubling time of regenerating clonogenic cells in the crypts of irradiated mouse small intestine. Potten CS, Taylor Y, Hendry JH, Int J Radiat Biol 1988 54 1041 1051 10.1080/09553008814552421 2903885
-
(1988)
Int J Radiat Biol
, vol.54
, pp. 1041-1051
-
-
Potten, C.S.1
Taylor, Y.2
Hendry, J.H.3
-
63
-
-
0027194943
-
Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
-
8487053
-
Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. Shimada Y, Yoshino M, Wakui A, Nakao I, Futatsuki K, Sakata Y, Kombe M, Toguchi T, Ogawa N, the CPT-11 Gastrointestinal Cancer Study Group, J Clin Oncol 1993 11 909 913 8487053
-
(1993)
J Clin Oncol
, vol.11
, pp. 909-913
-
-
Shimada, Y.1
Yoshino, M.2
Wakui, A.3
Nakao, I.4
Futatsuki, K.5
Sakata, Y.6
Kombe, M.7
Toguchi, T.8
Ogawa, N.9
-
64
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
10.1038/nrc1369
-
The anti-angiogenic basis of metronomic chemotherapy. Kerbel RS, Kamen BA, Nature Rev Cancer 2004 4 423 436 10.1038/nrc1369
-
(2004)
Nature Rev Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
65
-
-
0034309182
-
Repopulation of tumour cells between cycles of chemotherapy: A neglected factor
-
10.1016/S1470-2045(00)00019-X 11905673
-
Repopulation of tumour cells between cycles of chemotherapy: a neglected factor. Davis AJ, Tannock IF, Lancet Oncol 2000 1 86 93 10.1016/S1470-2045(00) 00019-X 11905673
-
(2000)
Lancet Oncol
, vol.1
, pp. 86-93
-
-
Davis, A.J.1
Tannock, I.F.2
-
66
-
-
78149458151
-
Modelling of tumour repopulation after chemotherapy
-
10.1007/s13246-010-0026-4 20652783
-
Modelling of tumour repopulation after chemotherapy. Marcu L, Bezak E, Australas Phys Eng Sci Med 2010 33 265 270 10.1007/s13246-010-0026-4 20652783
-
(2010)
Australas Phys Eng Sci Med
, vol.33
, pp. 265-270
-
-
Marcu, L.1
Bezak, E.2
-
67
-
-
60449086469
-
Mouse models of colon cancer
-
10.1053/j.gastro.2008.12.049
-
Mouse models of colon cancer. Taketo MM, Edelman W, Gastroenterol 2009 136 780 798 10.1053/j.gastro.2008.12.049
-
(2009)
Gastroenterol
, vol.136
, pp. 780-798
-
-
Taketo, M.M.1
Edelman, W.2
-
68
-
-
60149102748
-
Mouse models for the study of colon carcinogenesis
-
19037092
-
Mouse models for the study of colon carcinogenesis. Rosenberg DW, Giardina C, Tanaka T, Carcinogenesis 2009 30 183 196 19037092
-
(2009)
Carcinogenesis
, vol.30
, pp. 183-196
-
-
Rosenberg, D.W.1
Giardina, C.2
Tanaka, T.3
-
69
-
-
76549117990
-
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment
-
10.1073/pnas.0908682107 20080688
-
Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Huang KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kumin A, Bronson RT, Mahmood U, Kucherlapati R, Proc Natl Acad Sci USA 2010 107 1565 1570 10.1073/pnas.0908682107 20080688
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1565-1570
-
-
Huang, K.E.1
Maricevich, M.A.2
Richard, L.G.3
Chen, W.Y.4
Richardson, M.P.5
Kumin, A.6
Bronson, R.T.7
Mahmood, U.8
Kucherlapati, R.9
-
70
-
-
66349121917
-
Adaptive therapy
-
Adaptive therapy. Gatenby R, Silva AS, Gilles RJ, Frieden BR, Cancer Res 2009 69 4849 4903
-
(2009)
Cancer Res
, vol.69
, pp. 4849-4903
-
-
Gatenby, R.1
Silva, A.S.2
Gilles, R.J.3
Frieden, B.R.4
-
71
-
-
84891836153
-
Radiotherapy
-
Atlanta, Georgia: American Cancer Society Inc Lenhard REJr, Osteen RT, Gansler T
-
Radiotherapy. Mieszkalski GB, Brady LW, Yaeger TE, Class R, Clinical oncology Atlanta, Georgia: American Cancer Society Inc, Lenhard REJr, Osteen RT, Gansler T, 2001 165 174
-
(2001)
Clinical Oncology
, pp. 165-174
-
-
Mieszkalski, G.B.1
Brady, L.W.2
Yaeger, T.E.3
Class, R.4
-
72
-
-
84878989676
-
Principles of dose, schedule, and combination chemotherapy
-
Hamilton, Ontario: BC Decker Inc Bast RCJr, Kuff DW, Pollock RE, Weichselbaum RR, Holland JF, Frei EIII 5
-
Principles of dose, schedule, and combination chemotherapy. Frei E III, Antiman KH, Cancer medicine Hamilton, Ontario: BC Decker Inc, Bast RCJr, Kuff DW, Pollock RE, Weichselbaum RR, Holland JF, Frei EIII, 5 2000 556 568
-
(2000)
Cancer Medicine
, pp. 556-568
-
-
Frei III, F.E.1
Antiman, K.H.2
-
73
-
-
84864936206
-
In silico modeling of treatment-induced tumour cell kill: Developments and advances
-
In silico modeling of treatment-induced tumour cell kill: developments and advances. Marcu LG, Harriss-Phillips WM, Comp Math Methods Med 2012 2012 960256
-
(2012)
Comp Math Methods Med
, vol.2012
, pp. 960256
-
-
Marcu, L.G.1
Harriss-Phillips, W.M.2
-
75
-
-
84990575555
-
Intestinal crypt proliferation. II. Computer modeling of mitotic index data provides further evidence for lateral and vertical cell migration in the absence of mitotic activity
-
3233644
-
Intestinal crypt proliferation. II. Computer modeling of mitotic index data provides further evidence for lateral and vertical cell migration in the absence of mitotic activity. Loeffler M, Potten CS, Paulus U, Glatzer J, Chwalinski S, Cell Tissue Kinet 1988 21 247 258 3233644
-
(1988)
Cell Tissue Kinet
, vol.21
, pp. 247-258
-
-
Loeffler, M.1
Potten, C.S.2
Paulus, U.3
Glatzer, J.4
Chwalinski, S.5
-
76
-
-
84990576541
-
Cell migration velocities in the crypts of the small intestine after cytotoxic insult are not dependent on mitotic activity
-
3026633
-
Cell migration velocities in the crypts of the small intestine after cytotoxic insult are not dependent on mitotic activity. Kaur P, Potten CS, Cell Tissue Kinet 1986 19 601 610 3026633
-
(1986)
Cell Tissue Kinet
, vol.19
, pp. 601-610
-
-
Kaur, P.1
Potten, C.S.2
-
77
-
-
78049378037
-
The intestinal-crypt casino
-
10.1038/4671055a 20981089
-
The intestinal-crypt casino. Verzi MP, Shivdasani RA, Nature 2010 467 1055 1056 10.1038/4671055a 20981089
-
(2010)
Nature
, vol.467
, pp. 1055-1056
-
-
Verzi, M.P.1
Shivdasani, R.A.2
-
78
-
-
69549138171
-
An integrative computational model for intestinal tissue renewal
-
10.1111/j.1365-2184.2009.00627.x 19622103
-
An integrative computational model for intestinal tissue renewal. van Leeuwen IMM, Mirams GR, Walter A, Fletcher A, Murray P, Osborne J, Varma S, Young SJ, Cooper J, Doyle B, Pitt-Francis J, Momtahan L, Pathmanathan P, Whiteley JP, Chapman SJ, Gavaghan DJ, Jensen OE, King JR, Maini PK, Waters SL, Byrne HM, Cell Prolif 2009 42 617 636 10.1111/j.1365-2184.2009.00627.x 19622103
-
(2009)
Cell Prolif
, vol.42
, pp. 617-636
-
-
Van Leeuwen, I.M.M.1
Mirams, G.R.2
Walter, A.3
Fletcher, A.4
Murray, P.5
Osborne, J.6
Varma, S.7
Young, S.J.8
Cooper, J.9
Doyle, B.10
Pitt-Francis, J.11
Momtahan, L.12
Pathmanathan, P.13
Whiteley, J.P.14
Chapman, S.J.15
Gavaghan, D.J.16
Jensen, O.E.17
King, J.R.18
Maini, P.K.19
Waters, S.L.20
Byrne, H.M.21
more..
-
79
-
-
77956896626
-
Computational model of cell positioning: Directed and collective migration in the intestinal crypt epithelium
-
Computational model of cell positioning: directed and collective migration in the intestinal crypt epithelium. Wong SY, Chiam K-H, Lim ST, Matsudaira P, J Royal Society Interface 2010 7 Suppl 3 351 S363
-
(2010)
J Royal Society Interface
, vol.7
, Issue.SUPPL. 3
-
-
Wong, S.Y.1
Chiam, K.-H.2
Lim, S.T.3
Matsudaira, P.4
-
80
-
-
0028589378
-
Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
-
Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis. Hall PA, Coates PJ, Ansari B, Hopwood D, Cell Sci 1994 104 3569 3577
-
(1994)
Cell Sci
, vol.104
, pp. 3569-3577
-
-
Hall, P.A.1
Coates, P.J.2
Ansari, B.3
Hopwood, D.4
-
81
-
-
84863704401
-
A Two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath
-
10.1371/journal.pcbi.1002515
-
A Two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath. Dunn S-J, Appleton PL, Nelson SA, Näthke IS, Gavaghan DJ, Osborne JM, PLoS Comp Biol 2012 8 1002515 10.1371/journal.pcbi.1002515
-
(2012)
PLoS Comp Biol
, vol.8
, pp. 51002515
-
-
Dunn, S.-J.1
Appleton, P.L.2
Nelson, S.A.3
Näthke, I.S.4
Gavaghan, D.J.5
Osborne, J.M.6
-
82
-
-
34247345257
-
Cell exfoliation in the human colon: Myth, reality, and implications for colorectal cancer screening
-
10.1002/ijc.22647 17351899
-
Cell exfoliation in the human colon: myth, reality, and implications for colorectal cancer screening. Loktionov A, Int J Cancer 2007 120 2281 2289 10.1002/ijc.22647 17351899
-
(2007)
Int J Cancer
, vol.120
, pp. 2281-2289
-
-
Loktionov, A.1
-
83
-
-
0033984235
-
The Ki-67 protein: From known and unknown
-
10.1002/(SICI)1097-4652(200003)182:3<311: AID-JCP1>3.0.CO;2-9 10653597
-
The Ki-67 protein: from known and unknown. Scholzen T, Gerdes J, J Cell Physiol 2000 182 311 322 10.1002/(SICI)1097-4652(200003)182:3<311::AID- JCP1>3.0.CO;2-9 10653597
-
(2000)
J Cell Physiol
, vol.182
, pp. 311-322
-
-
Scholzen, T.1
Gerdes, J.2
-
84
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Identification of stem cells in small intestine and colon by marker gene Lgr5. Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Cleavers H, Nature 2007 449 103 1008
-
(2007)
Nature
, vol.449
, pp. 103-1008
-
-
Barker, N.1
Van Es, J.H.2
Kuipers, J.3
Kujala, P.4
Van Den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
Cleavers, H.11
-
85
-
-
46249128798
-
Bmi1 is expressed in vivo in intestinal stem cells
-
10.1038/ng.165 18536716
-
Bmi1 is expressed in vivo in intestinal stem cells. Sangiori E, Capecchi MR, Nat Genet 2008 40 915 920 10.1038/ng.165 18536716
-
(2008)
Nat Genet
, vol.40
, pp. 915-920
-
-
Sangiori, E.1
Capecchi, M.R.2
-
86
-
-
0041699964
-
Expression of musashi-1 in human normal colon crypt cells
-
10.1023/A:1024763723240
-
Expression of musashi-1 in human normal colon crypt cells. Nishimura S, Wakabayashi N, Toyada K, Kashima K, Mitsufuji S, Digestive Diseases Sci 2003 48 1523 1529 10.1023/A:1024763723240
-
(2003)
Digestive Diseases Sci
, vol.48
, pp. 1523-1529
-
-
Nishimura, S.1
Wakabayashi, N.2
Toyada, K.3
Kashima, K.4
Mitsufuji, S.5
-
87
-
-
0012872309
-
Identification of a putative intestinal stem cell and early lineage marker; Musashi-1
-
10.1046/j.1432-0436.2003.700603.x 12558601
-
Identification of a putative intestinal stem cell and early lineage marker; musashi-1. Potten CS, Booth C, Tudor GL, Booth D, Brady G, Hurley P, Ashton G, Clarke R, Sakakibara S, Okano H, Differentiation 2003 71 28 41 10.1046/j.1432-0436.2003.700603.x 12558601
-
(2003)
Differentiation
, vol.71
, pp. 28-41
-
-
Potten, C.S.1
Booth, C.2
Tudor, G.L.3
Booth, D.4
Brady, G.5
Hurley, P.6
Ashton, G.7
Clarke, R.8
Sakakibara, S.9
Okano, H.10
-
88
-
-
65949112714
-
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
-
10.1158/0008-5472.CAN-08-4418 19336570
-
Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appleman H, Fields JZ, Wicha MS, Boman BM, Cancer Res 2009 69 3382 3389 10.1158/0008-5472.CAN-08-4418 19336570
-
(2009)
Cancer Res
, vol.69
, pp. 3382-3389
-
-
Huang, E.H.1
Hynes, M.J.2
Zhang, T.3
Ginestier, C.4
Dontu, G.5
Appleman, H.6
Fields, J.Z.7
Wicha, M.S.8
Boman, B.M.9
-
89
-
-
84859196824
-
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
-
10.1016/j.cell.2012.02.042 22464327
-
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Powell A, Wang Y, Li Y, Poulin EJ, Means AL, Wasington MK, Higginbotham JN, Jucheim A, Prasad N, Levy SE, Guo Y, Shyr Y, Aronow BJ, Hagis KM, Franklin JL, Coffey RJ, Cell 2012 149 146 158 10.1016/j.cell.2012.02.042 22464327
-
(2012)
Cell
, vol.149
, pp. 146-158
-
-
Powell, A.1
Wang, Y.2
Li, Y.3
Poulin, E.J.4
Means, A.L.5
Wasington, M.K.6
Higginbotham, J.N.7
Jucheim, A.8
Prasad, N.9
Levy, S.E.10
Guo, Y.11
Shyr, Y.12
Aronow, B.J.13
Hagis, K.M.14
Franklin, J.L.15
Coffey, R.J.16
-
90
-
-
70350444697
-
The stem cell of small intestinal crypts: Where are they?
-
The stem cell of small intestinal crypts: where are they? Potten CS, Gandara R, Mahida YR, Loeffler M, Wright NA, Cell Prolif 2009 42 732 750
-
(2009)
Cell Prolif
, vol.42
, pp. 732-750
-
-
Potten, C.S.1
Gandara, R.2
Mahida, Y.R.3
Loeffler, M.4
Wright, N.A.5
-
91
-
-
0023237102
-
Estimates of the number of clonogenic cells in crypts of murine small intestine
-
10.1007/BF02890247
-
Estimates of the number of clonogenic cells in crypts of murine small intestine. Potten CS, Hendry JH, Moore JV, Virchows Archiv B 1987 53 227 234 10.1007/BF02890247
-
(1987)
Virchows Archiv B
, vol.53
, pp. 227-234
-
-
Potten, C.S.1
Hendry, J.H.2
Moore, J.V.3
-
92
-
-
85087240499
-
Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas
-
10.1016/j.stem.2013.06.010 23827700
-
Continuous clonal labeling reveals small numbers of functional stem cells in intestinal crypts and adenomas. Kozar S, Morrissey E, Nicholson AM, van der Heijden M, Zecchini HI, Kemp R, Tavaré S, Vermeulen L, Winton DJ, Cell Stem Cell 2013 13 1 8 10.1016/j.stem.2013.06.010 23827700
-
(2013)
Cell Stem Cell
, vol.13
, pp. 1-8
-
-
Kozar, S.1
Morrissey, E.2
Nicholson, A.M.3
Van Der Heijden, M.4
Zecchini, H.I.5
Kemp, R.6
Tavaré, S.7
Vermeulen, L.8
Winton, D.J.9
-
93
-
-
34047226082
-
The stem cell population of the human colon crypt: Analysis via methylation patterns
-
10.1371/journal.pcbi.0030028
-
The stem cell population of the human colon crypt: analysis via methylation patterns. Nicolas PK-M, Kim D, Shibata D, Tavaré S, PLoS Comp Biol 2007 3 28 10.1371/journal.pcbi.0030028
-
(2007)
PLoS Comp Biol
, vol.3
, pp. 528
-
-
Nicolas, P.-M.1
Kim, D.2
Shibata, D.3
Tavaré, S.4
-
94
-
-
84867303343
-
A dynamical-systems view of stem cell biology
-
10.1126/science.1224311 23066073
-
A dynamical-systems view of stem cell biology. Furusawa C, Kaneko K, Science 2012 338 215 217 10.1126/science.1224311 23066073
-
(2012)
Science
, vol.338
, pp. 215-217
-
-
Furusawa, C.1
Kaneko, K.2
-
95
-
-
0020431245
-
A mathematical model for cell population kinetics in the intestine
-
A mathematical model for cell population kinetics in the intestine. Britton NF, Wright NA, Murray JD, J Theor Biol 1982 98 532 541
-
(1982)
J Theor Biol
, vol.98
, pp. 532-541
-
-
Britton, N.F.1
Wright, N.A.2
Murray, J.D.3
-
96
-
-
82755186509
-
Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers
-
10.1073/pnas.1107621108 22084071
-
Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers. Rodriguez-Brenes I, Komarova NL, Wodarz D, Proc Natl Acad Sci USA 2011 108 18983 18988 10.1073/pnas.1107621108 22084071
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18983-18988
-
-
Rodriguez-Brenes, I.1
Komarova, N.L.2
Wodarz, D.3
-
97
-
-
84859511877
-
Multispecies model of cell lineages and feedback control in solid tumors
-
Multispecies model of cell lineages and feedback control in solid tumors. Youssefpour H, Li X, Lander AD, Lowengrub JS, J Theoret Biol 2012 304 39 59
-
(2012)
J Theoret Biol
, vol.304
, pp. 39-59
-
-
Youssefpour, H.1
Li, X.2
Lander, A.D.3
Lowengrub, J.S.4
-
98
-
-
0026459767
-
A model of the control of cellular regeneration in the intestinal crypt after perturbation based solely on local stem cell regulation
-
10.1111/j.1365-2184.1992.tb01460.x 1457605
-
A model of the control of cellular regeneration in the intestinal crypt after perturbation based solely on local stem cell regulation. Paulus U, Potten CS, Loeffler M, Cell Prolif 1992 25 559 578 10.1111/j.1365-2184.1992.tb01460.x 1457605
-
(1992)
Cell Prolif
, vol.25
, pp. 559-578
-
-
Paulus, U.1
Potten, C.S.2
Loeffler, M.3
-
99
-
-
0018686090
-
Cell differentiation rates of Friend murine erythroleukemia variants isolated by sib selection
-
10.1007/BF01542693 294699
-
Cell differentiation rates of Friend murine erythroleukemia variants isolated by sib selection. Axelrod DE, Terry R, Kern F, Somatic Cell Genet 1979 5 539 549 10.1007/BF01542693 294699
-
(1979)
Somatic Cell Genet
, vol.5
, pp. 539-549
-
-
Axelrod, D.E.1
Terry, R.2
Kern, F.3
-
100
-
-
77953048986
-
Acute promyelocytic leukemia: A paradigm for differentiation therapy
-
Acute promyelocytic leukemia: a paradigm for differentiation therapy. Grimwade D, Mistry AR, Solomon E, Guidez F, Cancer Treatment Res 2010 145 219 235
-
(2010)
Cancer Treatment Res
, vol.145
, pp. 219-235
-
-
Grimwade, D.1
Mistry, A.R.2
Solomon, E.3
Guidez, F.4
-
101
-
-
84867326265
-
Solid tumor differentiation therapy - Is it possible?
-
22643847
-
Solid tumor differentiation therapy-is it possible? Cruz FD, Matushansky I, Oncotarget 2012 3 559 567 22643847
-
(2012)
Oncotarget
, vol.3
, pp. 559-567
-
-
Cruz, F.D.1
Matushansky, I.2
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