Evolutionary dynamics of feedback escape and the development of stem-cell-driven cancers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 47, 2011, Pages 18983-18988

  Rodriguez Brenes, Ignacio A ^a   Komarova, Natalia L ^a   Wodarz, Dominik ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Evolutionary biology; Mathematical biology

Indexed keywords

ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER STEM CELL; CARCINOGENESIS; COMPUTER MODEL; FEEDBACK SYSTEM; GENE MUTATION; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM;

ALGORITHMS; BIOLOGICAL EVOLUTION; CELL TRANSFORMATION, NEOPLASTIC; COMPUTATIONAL BIOLOGY; FEEDBACK, PHYSIOLOGICAL; HUMANS; MODELS, BIOLOGICAL; MUTATION; NEOPLASMS; NEOPLASTIC STEM CELLS;

EID: 82755186509     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1107621108     Document Type: Article

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