A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath

PLoS Computational Biology

Volumn 8, Issue 5, 2012, Pages

  Dunn, Sara Jane ^a,b   Appleton, Paul L ^c   Nelson, Scott A ^c   Näthke, Inke S ^c   Gavaghan, David J ^a   Osborne, James M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MICROSOFT RESEARCH   (United Kingdom)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUILDINGS; CELL CULTURE; CELL PROLIFERATION; COLLAGEN; DEFORMATION; DISEASES; MUSCULOSKELETAL SYSTEM; TISSUE;

BASEMENT MEMBRANE; CONNECTIVE TISSUES; EPITHELIAL CELLS; EPITHELIAL MONOLAYERS; GENETIC MUTATIONS; MECHANICAL SUPPORT; PHYSICAL INTERFACE; TEST TUBE; TISSUE LEVELS; TWO DIMENSIONAL MODEL;

STEM CELLS;

ANIMAL CELL; ANIMAL TISSUE; ANOIKIS; APOPTOSIS; ARTICLE; BASEMENT MEMBRANE; CELL ADHESION; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CELL FUNCTION; CELL INTERACTION; CELL LOSS; CELL MIGRATION; CELL MOTION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; CRYPT CELL; FIBROBLAST; GENE MUTATION; INTESTINE CRYPT; MITOSIS INHIBITION; MOUSE; NONHUMAN; PHENOTYPE; STEADY STATE; STEM CELL; STOMACH MUSCLE; TISSUE STRUCTURE; ANIMAL; BIOLOGICAL MODEL; CELL COMMUNICATION; COLON; COMPUTER SIMULATION; CYTOLOGY; HUMAN; PHYSIOLOGY;

ANIMALS; BASEMENT MEMBRANE; CELL COMMUNICATION; COLON; COMPUTER SIMULATION; FIBROBLASTS; HUMANS; MODELS, BIOLOGICAL;

EID: 84863704401     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002515     Document Type: Article

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