A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt

Journal of Theoretical Biology

Volumn 312, Issue , 2012, Pages 143-156

  Mirams, Gary R ^a   Fletcher, Alexander G ^a,b   Maini, Philip K ^a,b   Byrne, Helen M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Clonal expansion; Colorectal crypt; Mathematical model; Mutation; Stem cell

Indexed keywords

ADHESION; CANCER; CLONE; MUTATION; NUMERICAL MODEL; PROBABILITY; SIMULATION; STATISTICAL DISTRIBUTION; STOCHASTICITY; THEORETICAL STUDY;

ARTICLE; CELL ADHESION; CELL CLONE; CELL CYCLE; CELL FUNCTION; CELL METABOLISM; CELL MIGRATION; CELL MUTANT; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TRACKING; CELLULAR DISTRIBUTION; COLORECTAL CANCER; CONTROLLED STUDY; CRYPT CELL; GEOMETRY; HOMEOSTASIS; MATHEMATICAL MODEL; MUTATIONAL ANALYSIS; POPULATION DYNAMICS; PRIORITY JOURNAL; PROCESS MODEL; PROGENY; REGULATORY MECHANISM; SENSITIVITY ANALYSIS; STOCHASTIC MODEL; THEORETICAL STUDY; WNT SIGNALING PATHWAY;

ALGORITHMS; CELL ADHESION; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CLONE CELLS; COLON; COMPUTER SIMULATION; EPITHELIAL CELLS; HUMANS; INTESTINAL MUCOSA; MODELS, BIOLOGICAL; MUTATION;

EID: 84865293885     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2012.08.002     Document Type: Article

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