Mathematical modeling of cell population dynamics in the colonic crypt and in colorectal cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 10, 2007, Pages 4008-4013

  Johnston, Matthew D ^a   Edwards, Carina M ^a   Bodmer, Walter F ^b   Maini, Philip K ^a,c   Chapman, S Jonathan ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Age structure; Feedback; Mutations; Structural stability

Indexed keywords

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL COUNT; CELL DIFFERENTIATION; CELL DIVISION; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; COLORECTAL CANCER; EPIGENETICS; GENE MUTATION; HOMEOSTASIS; INTESTINE CRYPT; MATHEMATICAL MODEL; POPULATION DYNAMICS; PRIORITY JOURNAL; STEM CELL; BIOLOGICAL MODEL; CELL TRANSFORMATION; COLON; COLORECTAL TUMOR; CYTOLOGY; FEEDBACK SYSTEM; GENETICS; HUMAN; MUTATION; PATHOLOGY; PHYSIOLOGY; STATISTICAL MODEL; THEORETICAL MODEL;

CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLORECTAL NEOPLASMS; FEEDBACK, BIOCHEMICAL; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL; MODELS, STATISTICAL; MODELS, THEORETICAL; MUTATION; STEM CELLS;

EID: 34247267072     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0611179104     Document Type: Article

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