A human pluripotent carcinoma stem cell-based model for in vitro developmental neurotoxicity testing: Effects of methylmercury, lead and aluminum evaluated by gene expression studies

International Journal of Developmental Neuroscience

Volumn 31, Issue 7, 2013, Pages 679-691

  Laurenza, Incoronata ^a   Pallocca, Giorgia ^a   Mennecozzi, Milena ^a   Scelfo, Bibiana ^a   Pamies, David ^a   Bal Price, Anna ^a  

^a JOINT RESEARCH CENTRE   (Italy)

Author keywords

Developmental neurotoxicity; Gene expression; Human stem cells derived model; Neurotoxicants

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR ALPHA1; ALUMINUM NITRATE; BETA ACTIN; BETA TUBULIN; BETA3 TUBULIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMATE RECEPTOR 1; LEAD CHLORIDE; MESSENGER RNA; METHYLMERCURIC CHLORIDE; MICROTUBULE ASSOCIATED PROTEIN 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NESTIN; NEUROFILAMENT PROTEIN; SYNAPTOPHYSIN; TAU PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASTROCYTE; CANCER STEM CELL; CELL DIFFERENTIATION; CELL TYPE; CONCENTRATION (PARAMETERS); CYTOTOXICITY; EXPERIMENTAL MODEL; GENE EXPRESSION; GLIAL CELL CULTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL CULTURE; NEUROTOXICITY; PHENOTYPE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; TOXICITY TESTING;

DEVELOPMENTAL NEUROTOXICITY; GENE EXPRESSION; HUMAN STEM CELLS DERIVED MODEL; NEUROTOXICANTS;

ACTION POTENTIALS; ALUMINUM; CARCINOMA; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEAD; METHYLMERCURY COMPOUNDS; NEOPLASTIC STEM CELLS; NERVE TISSUE PROTEINS; RECEPTORS, AMPA; RECEPTORS, GABA; TAU PROTEINS; TIME FACTORS;

EID: 84887606653     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2013.03.002     Document Type: Article

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