Protective effects of MK-801 on methylmercury-induced neuronal injury in rat cerebral cortex: Involvement of oxidative stress and glutamate metabolism dysfunction

Toxicology

Volumn 300, Issue 3, 2012, Pages 112-120

  Xu, Bin ^a   Xu, Zhao Fa ^a   Deng, Yu ^a   Liu, Wei ^a   Yang, Hai Bo ^a   Wei, Yan Gang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Glutamate metabolism; Methylmercury; MK 801; Neurotoxicity; Oxidative stress

Indexed keywords

DIZOCILPINE; GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MERCURY; METHYLMERCURY; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGIC SKIN REACTION; LIPID PEROXIDATION; MALE; NERVE CELL; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

ANIMALS; APOPTOSIS; CEREBRAL CORTEX; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; GLUTAMIC ACID; MALE; MERCURY POISONING, NERVOUS SYSTEM; METHYLMERCURY COMPOUNDS; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

ANIMALIA; RATTUS;

EID: 84864051562     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.06.006     Document Type: Article

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