A feed-forward loop involving Trib3, Akt and FoxO mediates death of NGF-deprived neurons

Cell Death and Differentiation

Volumn 20, Issue 12, 2013, Pages 1719-1730

  Zareen, N ^a   Biswas, S C ^b   Greene, L A ^a  

^a NewYork Presbyterian Hospital   (United States)

^b INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Akt; apoptosis; FoxO; NGF; Trib3

Indexed keywords

CELL PROTEIN; MESSENGER RNA; NERVE GROWTH FACTOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR FOXO; TRIB3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; GENE ACTIVATION; GENE INDUCTION; GENE OVEREXPRESSION; GENE SILENCING; INTRACELLULAR SIGNALING; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; RAT;

ANIMALS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DEATH; CELL NUCLEUS; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKDOWN TECHNIQUES; HEK293 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; NERVE GROWTH FACTOR; NEURONS; PC12 CELLS; PHOSPHORYLATION; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SUBSTRATE SPECIFICITY;

EID: 84887603458     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2013.128     Document Type: Article

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