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Volumn 128, Issue 6, 2013, Pages 434-447

The neurobiological correlates of childhood adversity and implications for treatment

Author keywords

Childhood abuse; Early life stress; Neurobiology; Treatment

Indexed keywords

ADRENALIN; ARGIPRESSIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CYCLOSERINE; FLUOXETINE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE; NEFAZODONE; NEUROTROPHIC FACTOR; NEUROTROPHIN; PLACEBO; PROPRANOLOL; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG; VASOPRESSIN RECEPTOR ANTAGONIST; VASOPRESSIN V1B RECEPTOR ANTAGONIST;

EID: 84887401317     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12143     Document Type: Article
Times cited : (106)

References (107)
  • 1
    • 76149141815 scopus 로고    scopus 로고
    • Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: associations with first onset of DSM-IV disorders
    • Green JG, McLaughlin KA, Berglund PA et al. Childhood adversities and adult psychiatric disorders in the national comorbidity survey replication I: associations with first onset of DSM-IV disorders. Arch Gen Psychiatry 2010;67:113-123.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 113-123
    • Green, J.G.1    McLaughlin, K.A.2    Berglund, P.A.3
  • 2
    • 0037841962 scopus 로고    scopus 로고
    • Interventions for foster parents: implications for developmental theory
    • Dozier M, Albus K, Fisher PA, Sepulveda S. Interventions for foster parents: implications for developmental theory. Dev Psychopathol 2002;14:843-860.
    • (2002) Dev Psychopathol , vol.14 , pp. 843-860
    • Dozier, M.1    Albus, K.2    Fisher, P.A.3    Sepulveda, S.4
  • 3
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • Lupien SJ, McEwen BS, Gunnar MR, Heim C. Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 2009;10:434-445.
    • (2009) Nat Rev Neurosci , vol.10 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 4
    • 77956635226 scopus 로고    scopus 로고
    • Research review: the neurobiology and genetics of maltreatment and adversity
    • McCrory E, De Brito SA, Viding E. Research review: the neurobiology and genetics of maltreatment and adversity. J Child Psychol Psychiatry 2010;51:1079-1095.
    • (2010) J Child Psychol Psychiatry , vol.51 , pp. 1079-1095
    • McCrory, E.1    De Brito, S.A.2    Viding, E.3
  • 5
    • 33847753969 scopus 로고    scopus 로고
    • Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights
    • Kaffman A, Meaney MJ. Neurodevelopmental sequelae of postnatal maternal care in rodents: clinical and research implications of molecular insights. J Child Psychol Psychiatry 2007;48:224-244.
    • (2007) J Child Psychol Psychiatry , vol.48 , pp. 224-244
    • Kaffman, A.1    Meaney, M.J.2
  • 6
    • 0034454682 scopus 로고    scopus 로고
    • How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
    • Sapolsky RM, Romero LM, Munck AU. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev 2000;21:55-89.
    • (2000) Endocr Rev , vol.21 , pp. 55-89
    • Sapolsky, R.M.1    Romero, L.M.2    Munck, A.U.3
  • 8
    • 40849133755 scopus 로고    scopus 로고
    • Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators
    • McEwen BS. Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol 2008;583:174-185.
    • (2008) Eur J Pharmacol , vol.583 , pp. 174-185
    • McEwen, B.S.1
  • 9
    • 0035875146 scopus 로고    scopus 로고
    • The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
    • Heim C, Nemeroff CB. The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 2001;49:1023-1039.
    • (2001) Biol Psychiatry , vol.49 , pp. 1023-1039
    • Heim, C.1    Nemeroff, C.B.2
  • 10
    • 0036891102 scopus 로고    scopus 로고
    • Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse
    • Rinne T, De Kloet ER, Wouters L, Goekoop JG, Derijk RH, Van den Brink W. Hyperresponsiveness of hypothalamic-pituitary-adrenal axis to combined dexamethasone/corticotropin-releasing hormone challenge in female borderline personality disorder subjects with a history of sustained childhood abuse. Biol Psychiatry 2002;52:1102-1112.
    • (2002) Biol Psychiatry , vol.52 , pp. 1102-1112
    • Rinne, T.1    De Kloet, E.R.2    Wouters, L.3    Goekoop, J.G.4    Derijk, R.H.5    Van Den Brink, W.6
  • 11
    • 77957359431 scopus 로고    scopus 로고
    • Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression
    • Kunugi H, Hori H, Adachi N, Numakawa T. Interface between hypothalamic-pituitary-adrenal axis and brain-derived neurotrophic factor in depression. Psychiatry Clin Neurosci 2010;64:447-459.
    • (2010) Psychiatry Clin Neurosci , vol.64 , pp. 447-459
    • Kunugi, H.1    Hori, H.2    Adachi, N.3    Numakawa, T.4
  • 12
    • 70449413781 scopus 로고    scopus 로고
    • Status of glucocorticoid alterations in post-traumatic stress disorder
    • Yehuda R. Status of glucocorticoid alterations in post-traumatic stress disorder. Ann N Y Acad Sci 2009;1179:56-69.
    • (2009) Ann N Y Acad Sci , vol.1179 , pp. 56-69
    • Yehuda, R.1
  • 13
    • 77958578685 scopus 로고    scopus 로고
    • Neurobiological and psychiatric consequences of child abuse and neglect
    • Heim C, Shugart M, Craighead WE, Nemeroff CB. Neurobiological and psychiatric consequences of child abuse and neglect. Dev Psychobiol 2010;52:671-690.
    • (2010) Dev Psychobiol , vol.52 , pp. 671-690
    • Heim, C.1    Shugart, M.2    Craighead, W.E.3    Nemeroff, C.B.4
  • 15
    • 44349145243 scopus 로고    scopus 로고
    • Childhood parental loss and adult hypothalamic-pituitary-adrenal function
    • Tyrka AR, Wier L, Price LH et al. Childhood parental loss and adult hypothalamic-pituitary-adrenal function. Biol Psychiatry 2008;63:1147-1154.
    • (2008) Biol Psychiatry , vol.63 , pp. 1147-1154
    • Tyrka, A.R.1    Wier, L.2    Price, L.H.3
  • 16
    • 0034623491 scopus 로고    scopus 로고
    • Long-term neuroendocrine effects of childhood maltreatment
    • Heim C, Newport DJ, Miller AH, Nemeroff CB. Long-term neuroendocrine effects of childhood maltreatment. JAMA 2000;284:2321.
    • (2000) JAMA , vol.284 , pp. 2321
    • Heim, C.1    Newport, D.J.2    Miller, A.H.3    Nemeroff, C.B.4
  • 17
    • 34447629382 scopus 로고    scopus 로고
    • Physiology and neurobiology of stress and adaptation: central role of the brain
    • McEwen BS. Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev 2007;87:873-904.
    • (2007) Physiol Rev , vol.87 , pp. 873-904
    • McEwen, B.S.1
  • 19
    • 59649109108 scopus 로고    scopus 로고
    • Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise
    • Duman CH, Schlesinger L, Terwilliger R, Russell DS, Newton SS, Duman RS. Peripheral insulin-like growth factor-I produces antidepressant-like behavior and contributes to the effect of exercise. Behav Brain Res 2009;198:366-371.
    • (2009) Behav Brain Res , vol.198 , pp. 366-371
    • Duman, C.H.1    Schlesinger, L.2    Terwilliger, R.3    Russell, D.S.4    Newton, S.S.5    Duman, R.S.6
  • 20
    • 77958021917 scopus 로고    scopus 로고
    • Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models
    • Schmidt HD, Duman RS. Peripheral BDNF produces antidepressant-like effects in cellular and behavioral models. Neuropsychopharmacology 2010;35:2378-2391.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2378-2391
    • Schmidt, H.D.1    Duman, R.S.2
  • 21
    • 77953102584 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor and suicide pathogenesis
    • Dwivedi Y. Brain-derived neurotrophic factor and suicide pathogenesis. Ann Med 2010;42:87-96.
    • (2010) Ann Med , vol.42 , pp. 87-96
    • Dwivedi, Y.1
  • 22
    • 49749101642 scopus 로고    scopus 로고
    • Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications
    • Sen S, Duman R, Sanacora G. Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications. Biol Psychiatry 2008;64:527-532.
    • (2008) Biol Psychiatry , vol.64 , pp. 527-532
    • Sen, S.1    Duman, R.2    Sanacora, G.3
  • 23
    • 79952282659 scopus 로고    scopus 로고
    • The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met
    • Elzinga BM, Molendijk ML, Oude Voshaar RC et al. The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val66Met. Psychopharmacology 2011;214:319-328.
    • (2011) Psychopharmacology , vol.214 , pp. 319-328
    • Elzinga, B.M.1    Molendijk, M.L.2    Oude Voshaar, R.C.3
  • 24
    • 84862006167 scopus 로고    scopus 로고
    • Childhood trauma and platelet brain-derived neurotrophic factor (BDNF) after a three month follow-up in patients with major depressive disorder
    • Jeon HJ, Kang ES, Lee EH et al. Childhood trauma and platelet brain-derived neurotrophic factor (BDNF) after a three month follow-up in patients with major depressive disorder. J Psychiatr Res 2012;46:966-972.
    • (2012) J Psychiatr Res , vol.46 , pp. 966-972
    • Jeon, H.J.1    Kang, E.S.2    Lee, E.H.3
  • 25
    • 84555220553 scopus 로고    scopus 로고
    • Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume
    • Mondelli V, Cattaneo A, Belvederi Murri M et al. Stress and inflammation reduce brain-derived neurotrophic factor expression in first-episode psychosis: a pathway to smaller hippocampal volume. J Clin Psychiatry 2011;72:1677-1684.
    • (2011) J Clin Psychiatry , vol.72 , pp. 1677-1684
    • Mondelli, V.1    Cattaneo, A.2    Belvederi Murri, M.3
  • 26
    • 84860298178 scopus 로고    scopus 로고
    • The impact of childhood maltreatment: a review of neurobiological and genetic factors
    • McCrory E, De Brito SA, Viding E. The impact of childhood maltreatment: a review of neurobiological and genetic factors. Front Psychiatry 2011;2:48.
    • (2011) Front Psychiatry , vol.2 , pp. 48
    • McCrory, E.1    De Brito, S.A.2    Viding, E.3
  • 27
    • 84859064637 scopus 로고    scopus 로고
    • Neuroimaging of child abuse: a critical review
    • Hart H, Rubia K. Neuroimaging of child abuse: a critical review. Front Hum Neurosci 2012;6:52.
    • (2012) Front Hum Neurosci , vol.6 , pp. 52
    • Hart, H.1    Rubia, K.2
  • 28
    • 80053956681 scopus 로고    scopus 로고
    • How understanding the neurobiology of complex post-traumatic stress disorder can inform clinical practice: a social cognitive and affective neuroscience approach
    • Lanius RA, Bluhm RL, Frewen PA. How understanding the neurobiology of complex post-traumatic stress disorder can inform clinical practice: a social cognitive and affective neuroscience approach. Acta Psychiatr Scand 2011;124:331-348.
    • (2011) Acta Psychiatr Scand , vol.124 , pp. 331-348
    • Lanius, R.A.1    Bluhm, R.L.2    Frewen, P.A.3
  • 30
    • 70349974171 scopus 로고    scopus 로고
    • Posttraumatic stress disorder: the role of medial prefrontal cortex and amygdala
    • Koenigs M, Grafman J. Posttraumatic stress disorder: the role of medial prefrontal cortex and amygdala. Neuroscientist 2009;15:540-548.
    • (2009) Neuroscientist , vol.15 , pp. 540-548
    • Koenigs, M.1    Grafman, J.2
  • 31
    • 77955660459 scopus 로고    scopus 로고
    • Decreased prefrontal cortical volume associated with increased bedtime cortisol in traumatized youth
    • Carrion VG, Weems CF, Richert K, Hoffman BC, Reiss AL. Decreased prefrontal cortical volume associated with increased bedtime cortisol in traumatized youth. Biol Psychiatry 2010;68:491-493.
    • (2010) Biol Psychiatry , vol.68 , pp. 491-493
    • Carrion, V.G.1    Weems, C.F.2    Richert, K.3    Hoffman, B.C.4    Reiss, A.L.5
  • 32
    • 33947132080 scopus 로고    scopus 로고
    • Stress predicts brain changes in children: a pilot longitudinal study on youth stress, posttraumatic stress disorder, and the hippocampus
    • Carrion VG, Weems CF, Reiss AL. Stress predicts brain changes in children: a pilot longitudinal study on youth stress, posttraumatic stress disorder, and the hippocampus. Pediatrics 2007;119:509-516.
    • (2007) Pediatrics , vol.119 , pp. 509-516
    • Carrion, V.G.1    Weems, C.F.2    Reiss, A.L.3
  • 35
    • 79952280719 scopus 로고    scopus 로고
    • Effects of early life stress on cognitive and affective function: an integrated review of human literature
    • Pechtel P, Pizzagalli DA. Effects of early life stress on cognitive and affective function: an integrated review of human literature. Psychopharmacology 2011;214:55-70.
    • (2011) Psychopharmacology , vol.214 , pp. 55-70
    • Pechtel, P.1    Pizzagalli, D.A.2
  • 36
    • 72749120596 scopus 로고    scopus 로고
    • Neuropsychological findings in childhood neglect and their relationships to pediatric PTSD
    • De Bellis MD, Hooper SR, Spratt EG, Woolley DP. Neuropsychological findings in childhood neglect and their relationships to pediatric PTSD. J Int Neuropsychol Soc 2009;15:868-878.
    • (2009) J Int Neuropsychol Soc , vol.15 , pp. 868-878
    • De Bellis, M.D.1    Hooper, S.R.2    Spratt, E.G.3    Woolley, D.P.4
  • 38
    • 84855983525 scopus 로고    scopus 로고
    • Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging
    • Dannlowski U, Stuhrmann A, Beutelmann V et al. Limbic scars: long-term consequences of childhood maltreatment revealed by functional and structural magnetic resonance imaging. Biol Psychiatry 2012;71:286-293.
    • (2012) Biol Psychiatry , vol.71 , pp. 286-293
    • Dannlowski, U.1    Stuhrmann, A.2    Beutelmann, V.3
  • 39
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffitt TE et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003;301:386-389.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3
  • 40
    • 58149308050 scopus 로고    scopus 로고
    • Gene X environment interactions at the serotonin transporter locus
    • Munafo MR, Durrant C, Lewis G, Flint J. Gene X environment interactions at the serotonin transporter locus. Biol Psychiatry 2009;65:211-219.
    • (2009) Biol Psychiatry , vol.65 , pp. 211-219
    • Munafo, M.R.1    Durrant, C.2    Lewis, G.3    Flint, J.4
  • 41
    • 67649206975 scopus 로고    scopus 로고
    • Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis
    • Risch N, Herrell R, Lehner T et al. Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA 2009;301:2462-2471.
    • (2009) JAMA , vol.301 , pp. 2462-2471
    • Risch, N.1    Herrell, R.2    Lehner, T.3
  • 42
    • 77951854270 scopus 로고    scopus 로고
    • Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits
    • Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE. Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry 2010;167:509-527.
    • (2010) Am J Psychiatry , vol.167 , pp. 509-527
    • Caspi, A.1    Hariri, A.R.2    Holmes, A.3    Uher, R.4    Moffitt, T.E.5
  • 43
    • 79952033418 scopus 로고    scopus 로고
    • The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation
    • Karg K, Burmeister M, Shedden K, Sen S. The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta-analysis revisited: evidence of genetic moderation. Arch Gen Psychiatry 2011;68:444-454.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 444-454
    • Karg, K.1    Burmeister, M.2    Shedden, K.3    Sen, S.4
  • 44
    • 79952282874 scopus 로고    scopus 로고
    • Gene-environment interactions: early life stress and risk for depressive and anxiety disorders
    • Nugent NR, Tyrka AR, Carpenter LL, Price LH. Gene-environment interactions: early life stress and risk for depressive and anxiety disorders. Psychopharmacology 2011;214:175-196.
    • (2011) Psychopharmacology , vol.214 , pp. 175-196
    • Nugent, N.R.1    Tyrka, A.R.2    Carpenter, L.L.3    Price, L.H.4
  • 45
    • 80054870734 scopus 로고    scopus 로고
    • A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women
    • Kranzler HR, Feinn R, Nelson EC et al. A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women. Am J Med Genet B Neuropsychiatr Genet 2011;156B:960-968.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156 B , pp. 960-968
    • Kranzler, H.R.1    Feinn, R.2    Nelson, E.C.3
  • 46
    • 78650617323 scopus 로고    scopus 로고
    • Childhood maltreatment, the corticotropin-releasing hormone receptor gene and adult depression in the general population
    • Grabe HJ, Schwahn C, Appel K et al. Childhood maltreatment, the corticotropin-releasing hormone receptor gene and adult depression in the general population. Am J Med Genet B Neuropsychiatr Genet 2010;153B:1483-1493.
    • (2010) Am J Med Genet B Neuropsychiatr Genet , vol.153 B , pp. 1483-1493
    • Grabe, H.J.1    Schwahn, C.2    Appel, K.3
  • 47
    • 80054961775 scopus 로고    scopus 로고
    • Interactive effects of corticotropin releasing hormone receptor 1, serotonin transporter linked polymorphic region, and child maltreatment on diurnal cortisol regulation and internalizing symptomatology
    • Cicchetti D, Rogosch FA, Oshri A. Interactive effects of corticotropin releasing hormone receptor 1, serotonin transporter linked polymorphic region, and child maltreatment on diurnal cortisol regulation and internalizing symptomatology. Dev Psychopathol 2011;23:1125-1138.
    • (2011) Dev Psychopathol , vol.23 , pp. 1125-1138
    • Cicchetti, D.1    Rogosch, F.A.2    Oshri, A.3
  • 48
    • 69949091530 scopus 로고    scopus 로고
    • Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity
    • Tyrka AR, Price LH, Gelernter J, Schepker C, Anderson GM, Carpenter LL. Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity. Biol Psychiatry 2009;66:681-685.
    • (2009) Biol Psychiatry , vol.66 , pp. 681-685
    • Tyrka, A.R.1    Price, L.H.2    Gelernter, J.3    Schepker, C.4    Anderson, G.M.5    Carpenter, L.L.6
  • 49
    • 84860625810 scopus 로고    scopus 로고
    • Gene-environment interaction in major depression and antidepressant treatment response
    • Keers R, Uher R. Gene-environment interaction in major depression and antidepressant treatment response. Curr Psychiatry Rep 2012;14:129-137.
    • (2012) Curr Psychiatry Rep , vol.14 , pp. 129-137
    • Keers, R.1    Uher, R.2
  • 50
    • 79953042396 scopus 로고    scopus 로고
    • Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project
    • Keers R, Uher R, Huezo-Diaz P et al. Interaction between serotonin transporter gene variants and life events predicts response to antidepressants in the GENDEP project. Pharmacogenomics J 2011;11:138-145.
    • (2011) Pharmacogenomics J , vol.11 , pp. 138-145
    • Keers, R.1    Uher, R.2    Huezo-Diaz, P.3
  • 51
    • 70549104872 scopus 로고    scopus 로고
    • Dynamic DNA methylation programs persistent adverse effects of early-life stress
    • Murgatroyd C, Patchev AV, Wu Y et al. Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat Neurosci 2009;12:1559-1566.
    • (2009) Nat Neurosci , vol.12 , pp. 1559-1566
    • Murgatroyd, C.1    Patchev, A.V.2    Wu, Y.3
  • 52
  • 53
    • 60749105468 scopus 로고    scopus 로고
    • Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
    • McGowan PO, Sasaki A, D'Alessio AC et al. Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nat Neurosci 2009;12:342-348.
    • (2009) Nat Neurosci , vol.12 , pp. 342-348
    • McGowan, P.O.1    Sasaki, A.2    D'Alessio, A.C.3
  • 54
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander TF, Weinberg J, Papsdorf M, Grunau R, Misri S, Devlin AM. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 2008;3:97-106.
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 55
    • 79960649740 scopus 로고    scopus 로고
    • Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor
    • Radtke KM, Ruf M, Gunter HM et al. Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor. Transl Psychiatry 2011;1:e21.
    • (2011) Transl Psychiatry , vol.1
    • Radtke, K.M.1    Ruf, M.2    Gunter, H.M.3
  • 56
    • 84856277610 scopus 로고    scopus 로고
    • Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults
    • Tyrka AR, Price LH, Marsit C, Walters OC, Carpenter LL. Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adults. PLoS ONE 2012;7:e30148.
    • (2012) PLoS ONE , vol.7
    • Tyrka, A.R.1    Price, L.H.2    Marsit, C.3    Walters, O.C.4    Carpenter, L.L.5
  • 57
    • 79955782889 scopus 로고    scopus 로고
    • Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity
    • Ursini G, Bollati V, Fazio L et al. Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity. J Neurosci 2011;31:6692-6698.
    • (2011) J Neurosci , vol.31 , pp. 6692-6698
    • Ursini, G.1    Bollati, V.2    Fazio, L.3
  • 58
    • 70349954993 scopus 로고    scopus 로고
    • Adverse childhood experiences and the risk of premature mortality
    • Brown DW, Anda RF, Tiemeier H et al. Adverse childhood experiences and the risk of premature mortality. Am J Prev Med 2009;37:389-396.
    • (2009) Am J Prev Med , vol.37 , pp. 389-396
    • Brown, D.W.1    Anda, R.F.2    Tiemeier, H.3
  • 59
    • 63449108990 scopus 로고    scopus 로고
    • Adverse events in childhood and chronic widespread pain in adult life: results from the 1958 British Birth Cohort Study
    • Jones GT, Power C, Macfarlane GJ. Adverse events in childhood and chronic widespread pain in adult life: results from the 1958 British Birth Cohort Study. Pain 2009;143:92-96.
    • (2009) Pain , vol.143 , pp. 92-96
    • Jones, G.T.1    Power, C.2    Macfarlane, G.J.3
  • 60
    • 63049110712 scopus 로고    scopus 로고
    • Psychological and metabolic stress: a recipe for accelerated cellular aging?
    • Epel ES. Psychological and metabolic stress: a recipe for accelerated cellular aging? Hormones (Athens) 2009;8:7-22.
    • (2009) Hormones (Athens) , vol.8 , pp. 7-22
    • Epel, E.S.1
  • 62
    • 84862223548 scopus 로고    scopus 로고
    • Altered response to neuroendocrine challenge linked to indices of the metabolic syndrome in healthy adults
    • Tyrka AR, Walters OC, Price LH, Anderson GM, Carpenter LL. Altered response to neuroendocrine challenge linked to indices of the metabolic syndrome in healthy adults. Horm Metab Res 2012;44:543-549.
    • (2012) Horm Metab Res , vol.44 , pp. 543-549
    • Tyrka, A.R.1    Walters, O.C.2    Price, L.H.3    Anderson, G.M.4    Carpenter, L.L.5
  • 63
    • 48149093475 scopus 로고    scopus 로고
    • A functional genomic fingerprint of chronic stress in humans: blunted glucocorticoid and increased NF-kappaB signaling
    • Miller GE, Chen E, Sze J et al. A functional genomic fingerprint of chronic stress in humans: blunted glucocorticoid and increased NF-kappaB signaling. Biol Psychiatry 2008;64:266-272.
    • (2008) Biol Psychiatry , vol.64 , pp. 266-272
    • Miller, G.E.1    Chen, E.2    Sze, J.3
  • 64
    • 84856111463 scopus 로고    scopus 로고
    • Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior
    • Haroon E, Raison CL, Miller AH. Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior. Neuropsychopharmacology 2012;37:137-162.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 137-162
    • Haroon, E.1    Raison, C.L.2    Miller, A.H.3
  • 66
    • 71549168934 scopus 로고    scopus 로고
    • Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers
    • Danese A, Moffitt TE, Harrington H et al. Adverse childhood experiences and adult risk factors for age-related disease: depression, inflammation, and clustering of metabolic risk markers. Arch Pediatr Adolesc Med 2009;163:1135-1143.
    • (2009) Arch Pediatr Adolesc Med , vol.163 , pp. 1135-1143
    • Danese, A.1    Moffitt, T.E.2    Harrington, H.3
  • 68
    • 10344229954 scopus 로고    scopus 로고
    • Accelerated telomere shortening in response to life stress
    • Epel ES, Blackburn EH, Lin J et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA 2004;101:17312-17315.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 17312-17315
    • Epel, E.S.1    Blackburn, E.H.2    Lin, J.3
  • 69
    • 1242284405 scopus 로고    scopus 로고
    • Validity of adult retrospective reports of adverse childhood experiences: review of the evidence
    • Hardt J, Rutter M. Validity of adult retrospective reports of adverse childhood experiences: review of the evidence. J Child Psychol Psychiatry 2004;45:260-273.
    • (2004) J Child Psychol Psychiatry , vol.45 , pp. 260-273
    • Hardt, J.1    Rutter, M.2
  • 70
    • 84857582541 scopus 로고    scopus 로고
    • Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis
    • Nanni V, Uher R, Danese A. Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis. Am J Psychiatry 2012;169:141-151.
    • (2012) Am J Psychiatry , vol.169 , pp. 141-151
    • Nanni, V.1    Uher, R.2    Danese, A.3
  • 71
    • 1442284526 scopus 로고    scopus 로고
    • Lifetime history of sexual abuse, clinical presentation, and outcome in a clinical trial for adolescent depression
    • Barbe RP, Bridge JA, Birmaher B, Kolko DJ, Brent DA. Lifetime history of sexual abuse, clinical presentation, and outcome in a clinical trial for adolescent depression. J Clin Psychiatry 2004;65:77-83.
    • (2004) J Clin Psychiatry , vol.65 , pp. 77-83
    • Barbe, R.P.1    Bridge, J.A.2    Birmaher, B.3    Kolko, D.J.4    Brent, D.A.5
  • 72
    • 79951856958 scopus 로고    scopus 로고
    • Impact of physical and sexual abuse on treatment response in the Treatment of Resistant Depression in Adolescent Study (TORDIA)
    • Shamseddeen W, Asarnow JR, Clarke G et al. Impact of physical and sexual abuse on treatment response in the Treatment of Resistant Depression in Adolescent Study (TORDIA). J Am Acad Child Adolesc Psychiatry 2011;50:293-301.
    • (2011) J Am Acad Child Adolesc Psychiatry , vol.50 , pp. 293-301
    • Shamseddeen, W.1    Asarnow, J.R.2    Clarke, G.3
  • 75
    • 10744223245 scopus 로고    scopus 로고
    • Differential responses to psychotherapy vs. pharmacotherapy in patients with chronic forms of major depression and childhood trauma
    • Nemeroff CB, Heim CM, Thase ME et al. Differential responses to psychotherapy vs. pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proc Natl Acad Sci USA 2003;100:14293-14296.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14293-14296
    • Nemeroff, C.B.1    Heim, C.M.2    Thase, M.E.3
  • 76
    • 79952235787 scopus 로고    scopus 로고
    • Long-term effect of combined interpersonal psychotherapy and pharmacotherapy in a randomized trial of depressed patients
    • Zobel I, Kech S, Van Calker D et al. Long-term effect of combined interpersonal psychotherapy and pharmacotherapy in a randomized trial of depressed patients. Acta Psychiatr Scand 2011;123:276-282.
    • (2011) Acta Psychiatr Scand , vol.123 , pp. 276-282
    • Zobel, I.1    Kech, S.2    Van Calker, D.3
  • 78
    • 79951879684 scopus 로고    scopus 로고
    • Dialectical behavior therapy for posttraumatic stress disorder related to childhood sexual abuse: a pilot study of an intensive residential treatment program
    • Steil R, Dyer A, Priebe K, Kleindienst N, Bohus M. Dialectical behavior therapy for posttraumatic stress disorder related to childhood sexual abuse: a pilot study of an intensive residential treatment program. J Trauma Stress 2011;24:102-106.
    • (2011) J Trauma Stress , vol.24 , pp. 102-106
    • Steil, R.1    Dyer, A.2    Priebe, K.3    Kleindienst, N.4    Bohus, M.5
  • 79
    • 82955178682 scopus 로고    scopus 로고
    • Prolonged exposure therapy: past, present, and future
    • Foa EB. Prolonged exposure therapy: past, present, and future. Depress Anxiety 2011;28:1043-1047.
    • (2011) Depress Anxiety , vol.28 , pp. 1043-1047
    • Foa, E.B.1
  • 80
    • 77955396910 scopus 로고    scopus 로고
    • Treatment for PTSD related to childhood abuse: a randomized controlled trial
    • Cloitre M, Stovall-Mcclough KC, Nooner K et al. Treatment for PTSD related to childhood abuse: a randomized controlled trial. Am J Psychiatry 2010;167:915-924.
    • (2010) Am J Psychiatry , vol.167 , pp. 915-924
    • Cloitre, M.1    Stovall-Mcclough, K.C.2    Nooner, K.3
  • 81
    • 77950246539 scopus 로고    scopus 로고
    • Memory reconsolidation: an update
    • Nader K, Einarsson EO. Memory reconsolidation: an update. Ann N Y Acad Sci 2010;1191:27-41.
    • (2010) Ann N Y Acad Sci , vol.1191 , pp. 27-41
    • Nader, K.1    Einarsson, E.O.2
  • 82
    • 84455171593 scopus 로고    scopus 로고
    • Fear erasure in mice requires synergy between antidepressant drugs and extinction training
    • Karpova NN, Pickenhagen A, Lindholm J et al. Fear erasure in mice requires synergy between antidepressant drugs and extinction training. Science 2011;334:1731-1734.
    • (2011) Science , vol.334 , pp. 1731-1734
    • Karpova, N.N.1    Pickenhagen, A.2    Lindholm, J.3
  • 83
    • 84857660543 scopus 로고    scopus 로고
    • NMDA receptors and fear extinction: implications for cognitive behavioral therapy
    • Davis M. NMDA receptors and fear extinction: implications for cognitive behavioral therapy. Dialogues Clin Neurosci 2011;13:463-474.
    • (2011) Dialogues Clin Neurosci , vol.13 , pp. 463-474
    • Davis, M.1
  • 84
    • 84861096785 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of d-cycloserine to enhance exposure therapy for posttraumatic stress disorder
    • Kleine RA, Hendriks GJ, Kusters WJ, Broekman TG, Van Minnen A. A randomized placebo-controlled trial of d-cycloserine to enhance exposure therapy for posttraumatic stress disorder. Biol Psychiatry 2012;71:962-968.
    • (2012) Biol Psychiatry , vol.71 , pp. 962-968
    • Kleine, R.A.1    Hendriks, G.J.2    Kusters, W.J.3    Broekman, T.G.4    Van Minnen, A.5
  • 85
    • 84864395164 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of d-cycloserine and exposure therapy for posttraumatic stress disorder
    • Litz BT, Salters-Pedneault K, Steenkamp MM et al. A randomized placebo-controlled trial of d-cycloserine and exposure therapy for posttraumatic stress disorder. J Psychiatr Res 2012;46:1184-1190.
    • (2012) J Psychiatr Res , vol.46 , pp. 1184-1190
    • Litz, B.T.1    Salters-Pedneault, K.2    Steenkamp, M.M.3
  • 86
    • 84863049769 scopus 로고    scopus 로고
    • Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery
    • Hoge EA, Worthington JJ, Nagurney JT et al. Effect of acute posttrauma propranolol on PTSD outcome and physiological responses during script-driven imagery. CNS Neurosci Ther 2012;18:21-27.
    • (2012) CNS Neurosci Ther , vol.18 , pp. 21-27
    • Hoge, E.A.1    Worthington, J.J.2    Nagurney, J.T.3
  • 87
    • 79960568421 scopus 로고    scopus 로고
    • Trauma reactivation under the influence of propranolol decreases posttraumatic stress symptoms and disorder: 3 open-label trials
    • Brunet A, Poundja J, Tremblay J et al. Trauma reactivation under the influence of propranolol decreases posttraumatic stress symptoms and disorder: 3 open-label trials. J Clin Psychopharmacol 2011;31:547-550.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 547-550
    • Brunet, A.1    Poundja, J.2    Tremblay, J.3
  • 88
    • 77952549409 scopus 로고    scopus 로고
    • Progress in corticotropin-releasing factor-1 antagonist development
    • Zorrilla EP, Koob GF. Progress in corticotropin-releasing factor-1 antagonist development. Drug Discov Today 2010;15:371-383.
    • (2010) Drug Discov Today , vol.15 , pp. 371-383
    • Zorrilla, E.P.1    Koob, G.F.2
  • 89
    • 84869213609 scopus 로고    scopus 로고
    • The vasopressin V1b receptor antagonist SSR149415 in the treatment of major depressive and generalized anxiety disorders: results from 4 randomized, double-blind, placebo-controlled studies
    • Griebel G, Beeske S, Stahl SM. The vasopressin V1b receptor antagonist SSR149415 in the treatment of major depressive and generalized anxiety disorders: results from 4 randomized, double-blind, placebo-controlled studies. J Clin Psychiatry 2012;73:1403-1411.
    • (2012) J Clin Psychiatry , vol.73 , pp. 1403-1411
    • Griebel, G.1    Beeske, S.2    Stahl, S.M.3
  • 90
    • 84861850317 scopus 로고    scopus 로고
    • Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?
    • Griebel G, Holsboer F. Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning? Nat Rev Drug Discov 2012;11:462-478.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 462-478
    • Griebel, G.1    Holsboer, F.2
  • 91
    • 77954958226 scopus 로고    scopus 로고
    • Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary-adrenocortical axis responsiveness to stress
    • Wulsin AC, Herman JP, Solomon MB. Mifepristone decreases depression-like behavior and modulates neuroendocrine and central hypothalamic-pituitary-adrenocortical axis responsiveness to stress. Psychoneuroendocrinology 2010;35:1100-1112.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 1100-1112
    • Wulsin, A.C.1    Herman, J.P.2    Solomon, M.B.3
  • 92
    • 79960955704 scopus 로고    scopus 로고
    • Systemic mifepristone blocks reconsolidation of cue-conditioned fear; propranolol prevents this effect
    • Pitman RK, Milad MR, Igoe SA et al. Systemic mifepristone blocks reconsolidation of cue-conditioned fear; propranolol prevents this effect. Behav Neurosci 2011;125:632-638.
    • (2011) Behav Neurosci , vol.125 , pp. 632-638
    • Pitman, R.K.1    Milad, M.R.2    Igoe, S.A.3
  • 93
    • 33645847829 scopus 로고    scopus 로고
    • The use of mifepristone in the treatment of neuropsychiatric disorders
    • Debattista C, Belanoff J. The use of mifepristone in the treatment of neuropsychiatric disorders. Trends Endocrinol Metab 2006;17:117-121.
    • (2006) Trends Endocrinol Metab , vol.17 , pp. 117-121
    • Debattista, C.1    Belanoff, J.2
  • 94
    • 79960612871 scopus 로고    scopus 로고
    • Efficacy and safety of mifepristone for the treatment of psychotic depression
    • Blasey CM, Block TS, Belanoff JK, Roe RL. Efficacy and safety of mifepristone for the treatment of psychotic depression. J Clin Psychopharmacol 2011;31:436-440.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 436-440
    • Blasey, C.M.1    Block, T.S.2    Belanoff, J.K.3    Roe, R.L.4
  • 95
    • 67650085258 scopus 로고    scopus 로고
    • Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus?
    • Kling MA, Coleman VH, Schulkin J. Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus? Depress Anxiety 2009;26:641-649.
    • (2009) Depress Anxiety , vol.26 , pp. 641-649
    • Kling, M.A.1    Coleman, V.H.2    Schulkin, J.3
  • 96
    • 78649687889 scopus 로고    scopus 로고
    • The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies
    • Zoladz JA, Pilc A. The effect of physical activity on the brain derived neurotrophic factor: from animal to human studies. J Physiol Pharmacol 2010;61:533-541.
    • (2010) J Physiol Pharmacol , vol.61 , pp. 533-541
    • Zoladz, J.A.1    Pilc, A.2
  • 97
    • 77955611775 scopus 로고    scopus 로고
    • Methylation matters: interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma
    • Van Ijzendoorn MH, Caspers K, Bakermans-Kranenburg MJ, Beach SR, Philibert R. Methylation matters: interaction between methylation density and serotonin transporter genotype predicts unresolved loss or trauma. Biol Psychiatry 2010;68:405-407.
    • (2010) Biol Psychiatry , vol.68 , pp. 405-407
    • Van Ijzendoorn, M.H.1    Caspers, K.2    Bakermans-Kranenburg, M.J.3    Beach, S.R.4    Philibert, R.5
  • 98
    • 84857366528 scopus 로고    scopus 로고
    • Therapygenetics: the 5HTTLPR and response to psychological therapy
    • Eley TC, Hudson JL, Creswell C et al. Therapygenetics: the 5HTTLPR and response to psychological therapy. Mol Psychiatry 2012;17:236-237.
    • (2012) Mol Psychiatry , vol.17 , pp. 236-237
    • Eley, T.C.1    Hudson, J.L.2    Creswell, C.3
  • 99
    • 84869089691 scopus 로고    scopus 로고
    • Epigenetic inheritance of disease and disease risk
    • Bohacek J, Mansuy IM. Epigenetic inheritance of disease and disease risk. Neuropsychopharmacology 2012;38:220-236.
    • (2012) Neuropsychopharmacology , vol.38 , pp. 220-236
    • Bohacek, J.1    Mansuy, I.M.2
  • 100
    • 77952887606 scopus 로고    scopus 로고
    • The epigenetics of social adversity in early life: implications for mental health outcomes
    • McGowan PO, Szyf M. The epigenetics of social adversity in early life: implications for mental health outcomes. Neurobiol Dis 2010;39:66-72.
    • (2010) Neurobiol Dis , vol.39 , pp. 66-72
    • McGowan, P.O.1    Szyf, M.2
  • 101
    • 79251578642 scopus 로고    scopus 로고
    • Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation
    • Gomez-Pinilla F, Zhuang Y, Feng J, Ying Z, Fan G. Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation. Eur J Neurosci 2011;33:383-390.
    • (2011) Eur J Neurosci , vol.33 , pp. 383-390
    • Gomez-Pinilla, F.1    Zhuang, Y.2    Feng, J.3    Ying, Z.4    Fan, G.5
  • 102
    • 84859571611 scopus 로고    scopus 로고
    • Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study
    • Miyaoka T, Wake R, Furuya M et al. Minocycline as adjunctive therapy for patients with unipolar psychotic depression: an open-label study. Prog Neuropsychopharmacol Biol Psychiatry 2012;37:222-226.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.37 , pp. 222-226
    • Miyaoka, T.1    Wake, R.2    Furuya, M.3
  • 103
    • 84878154348 scopus 로고    scopus 로고
    • Elevated ratio of arachidonic acid to long-chain omega-3 fatty acids predicts depression development following interferon-alpha treatment: relati onship with interleukin-6
    • Lotrich FE, Sears B, McNamara RK. Elevated ratio of arachidonic acid to long-chain omega-3 fatty acids predicts depression development following interferon-alpha treatment: relati onship with interleukin-6. Brain Behav Immun 2013;31:48-53.
    • (2013) Brain Behav Immun , vol.31 , pp. 48-53
    • Lotrich, F.E.1    Sears, B.2    McNamara, R.K.3
  • 104
    • 84871986003 scopus 로고    scopus 로고
    • A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers
    • Raison CL, Rutherford RE, Woolwine BJ et al. A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers. JAMA Psychiatry 2012;70:31-41.
    • (2012) JAMA Psychiatry , vol.70 , pp. 31-41
    • Raison, C.L.1    Rutherford, R.E.2    Woolwine, B.J.3
  • 105
    • 84863987293 scopus 로고    scopus 로고
    • Pioglitazone adjunctive therapy for moderate-to-severe major depressive disorder: randomized double-blind placebo-controlled trial
    • Sepanjnia K, Modabbernia A, Ashrafi M, Modabbernia MJ, Akhondzadeh S. Pioglitazone adjunctive therapy for moderate-to-severe major depressive disorder: randomized double-blind placebo-controlled trial. Neuropsychopharmacology 2012;37:2093-2100.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2093-2100
    • Sepanjnia, K.1    Modabbernia, A.2    Ashrafi, M.3    Modabbernia, M.J.4    Akhondzadeh, S.5
  • 106
    • 84870065602 scopus 로고    scopus 로고
    • Eicosapentaenoic acid appears to be the key omega-3 fatty acid component associated with efficacy in major depressive disorder: a critique of Bloch and Hannestad and updated meta-analysis
    • Martins JG, Bentsen H, Puri BK. Eicosapentaenoic acid appears to be the key omega-3 fatty acid component associated with efficacy in major depressive disorder: a critique of Bloch and Hannestad and updated meta-analysis. Mol Psychiatry 2012;17:1144-1149.
    • (2012) Mol Psychiatry , vol.17 , pp. 1144-1149
    • Martins, J.G.1    Bentsen, H.2    Puri, B.K.3
  • 107
    • 67349166480 scopus 로고    scopus 로고
    • Behavioral immunization: immunity to self-antigens contributes to psychological stress resilience
    • Lewitus GM, Schwartz M. Behavioral immunization: immunity to self-antigens contributes to psychological stress resilience. Mol Psychiatry 2009;14:532-536.
    • (2009) Mol Psychiatry , vol.14 , pp. 532-536
    • Lewitus, G.M.1    Schwartz, M.2


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