Interactive effects of corticotropin releasing hormone receptor 1, serotonin transporter linked polymorphic region, and child maltreatment on diurnal cortisol regulation and internalizing symptomatology

Development and Psychopathology

Volumn 23, Issue 4, 2011, Pages 1125-1138

  Cicchetti, Dante ^a   Rogosch, Fred A ^a   Oshri, Assaf ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR; CRF RECEPTOR TYPE 1; HYDROCORTISONE; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, HUMAN;

ADOLESCENT; ARTICLE; CHEMISTRY; CHILD; CHILD ABUSE; CIRCADIAN RHYTHM; DEPRESSION; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HUMAN; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SALIVA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; CHILD; CHILD ABUSE; CIRCADIAN RHYTHM; DEPRESSION; FEMALE; GENE-ENVIRONMENT INTERACTION; GENETIC ASSOCIATION STUDIES; HAPLOTYPES; HUMANS; HYDROCORTISONE; MALE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHIATRIC STATUS RATING SCALES; RECEPTORS, CORTICOTROPIN-RELEASING HORMONE; SALIVA; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 80054961775     PISSN: 09545794     EISSN: 14692198     Source Type: Journal    
DOI: 10.1017/S0954579411000599     Document Type: Article

References (88)

1. Achenbach, T. M. (1991). Manual of the Teacher's Report Form and 1991 profile. Burlington, VT: University of Vermont, Department of Psychiatry.
2. Ayoub, C. C., O'Connor, E., Rappolt-Schlichtmann, G., Fischer, K. W., Rogosch, F. A., Toth, S. L., et al. (2006). Cognitive and emotional differences in young maltreated children: A translational application of dynamic skill theory. Development and Psychopathology, 18, 679-706. (Pubitemid 44445157)
3. Barnett, D., Manly, J. T., & Cicchetti, D. (1993). Defining child maltreatment: The interface between policy and research. In D. Cicchetti & S. L. Toth (Eds.), Child abuse, child development, and social policy (pp. 7-74). Norwood, NJ: Ablex.
4. Berntson, G. G., & Cacioppo, J. T. (2007). Integrative physiology: Homeo- stasis, allostasis and the orchestration of systemic physiology. In J. T. Ca- cioppo, L. G. Tassinary, & G. G. Berntson (Eds.), Handbook ofpsycho- physiology (3rd ed., pp. 433-452). New York: Cambridge University Press.
5. Bradley, R. G., Binder, E. B., Epstein, M. P., Tang, Y., Nair, H. P., Liu, W., et al. (2008). Influence of child abuse on adult depression: Moderation by the corticotrophin-releasing hormone receptor gene. Archives of General Psychiatry, 65, 190-200. (Pubitemid 351214318)
6. Brown, G. W., & Harris, T. O. (2008). Depression and the serotonin transporter 5-HTTLPR polymorphism: A review and a hypothesis concerning gene-environment interaction. Journal of Affective Disorders, 111, 1-12.
7. Carpenter, L. L., Shattuck, T. T., Tyrka, A. R., Geracioti, T. D., & Price, L. H. (2010). Effect of childhood physical abuse on cortisol stress response. Psychopharmacology (Berlin), 214, 367-375.
8. Caspi, A., Hariri, A. R., Holmes, A., Uher, R., & Moffitt, T. E. (2010). Genetic sensitivity to the environment: The case of the serotonin transporter gene and its implications for studying complex diseases and traits. American Journal of Psychiatry, 167, 509-527.
9. Caspi, A., McClay, J., Moffitt, T., Mill, J., Martin, J., Craig, I. W., et al. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851-854. (Pubitemid 34839638)
10. Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H. L., et al. (2003). Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science, 301, 386-389. (Pubitemid 36877077)
11. Chrousos, G. P. (1998). Stressors, stress, and neuroendocrine integration of the adaptive response. The 1997 Hans Selye Memorial Lecture. Annals ofthe New York Academy ofSciences, 851 , 311-335.
12. Cicchetti, D. (1989). How research on child maltreatment has informed the study of child development: Perspectives from developmental psychopa- thology. In D. Cicchetti & V. Carlson (Eds.), Child maltreatment: Theory and research on the causes and consequences ofchild abuse and neglect ( pp. 377-431). New York: Cambridge University Press.
13. Cicchetti, D., & Curtis, W. J. (2005). An event-related potential (ERP) study of processing of affective facial expressions in young children who have experienced maltreatment during the first year of life. Development and Psychopathology, 17, 641-677.
14. Cicchetti, D., & Gunnar, M. R. (2008). Integrating biological processes into the design and evaluation of preventive interventions. Development and Psychopathology, 20, 737-743. (Pubitemid 352003596)
15. Cicchetti, D., & Manly, J. T. (1990). A personal perspective on conducting research with maltreating families: Problems and solutions. In G. Brody & I. Sigel (Eds.), Methods of family research: Families at risk (Vol. 2, pp. 87-133). Hillsdale, NJ: Erlbaum.
16. Cicchetti, D., & Rogosch, F. A. (1996). Equifinality and multifinality in developmental psychopathology. Development and Psychopathology, 8, 597-600.
17. Cicchetti, D., & Rogosch, F. A. (2001a). Diverse patterns of neuroendocrine activity in maltreated children. Development and Psychopathology, 13, 677-694.
18. Cicchetti, D., & Rogosch, F. A. (2001b). The impact of child maltreatment and psychopathology upon neuroendocrine functioning. Development and Psychopathology, 13, 783-804. (Pubitemid 33580419)
19. Cicchetti, D., Rogosch, F. A., Gunnar, M. R., & Toth, S. L. (2010). The differential impacts of early abuse on internalizing problems and diurnal cortisol activity in school-aged children. Child Development, 25, 252269.
20. Cicchetti, D., Rogosch, F. A., & Toth, S. L. (2006). Fostering secure attachment in infants in maltreating families through preventive interventions. Development and Psychopathology, 18, 623-650.
21. Cicchetti, D., Rogosch, F. A., Toth, S. L., & Sturge-Apple, M. L. (2011). Normalizing the development of cortisol regulation in maltreated infants through preventive interventions. Development and Psychopathology, 23, 789-800.
22. Cicchetti, D., & Toth, S. L. (2005). Child maltreatment. Annual Review of Clinical Psychology, 1, 409-438. (Pubitemid 43843957)
23. Cicchetti, D., Toth, S. L., & Manly, J. T. (2003). Maternal Maltreatment Interview. Unpublished manuscript.
24. Cicchetti, D., & Tucker, D. (1994). Development and self-regulatory structures of the mind. Development and Psychopathology, 6, 533-549.
25. Cicchetti, D., & Valentino, K. (2006). An ecological transactional perspective on child maltreatment: Failure of the average expectable environment and its influence upon child development. In D. Cicchetti & D. J. Cohen (Eds.), Developmental psychopathology (Vol. 3, 2nd ed., pp. 129-201). New York: Wiley.
26. Costa, P. T., & McCrae, R. R. (1992). The NEO-PI-R andNEO-FFImanual. Lutz, FL: Psychological Assessment Resources.
27. Curtis, W. J., & Cicchetti, D. (2011). Affective facial expression processing in young children who have experienced maltreatment during the first year of life: An event-related potential study. Development and Psycho- pathology, 23, 373-395.
28. Dahl, R., & Ryan, N. (1996). The psychobiology of adolescent depression. In D. Cicchetti & S. L. Toth (Eds.), Rochester Symposium on Developmental Psychopathology: Adolescence: Opportunities and challenges (Vol. 7, pp. 197-232). Rochester, NY: University of Rochester Press.
29. Danese, A., Moffitt, T. E., Pariante, C. M., Ambler, A., Poulton, R., & Caspi, A. (2008). Elevated inflammation levels in depressed adults with a history of childhood maltreatment. Archives of General Psychiatry, 65, 409-415.
30. Davies, P. T., Sturge-Apple, M. L., & Cicchetti, D. (2011). Interparental aggression and children's adrenocortical reactivity: Testing an evolutionary model of allostatic load. Development and Psychopathology, 23, 801814.
31. DeBellis, M. D., Baum, A. S., B irmaher, B., Keshavan, M. S., Eccard, C. H., Boring, A. M., et al. (1999a). Developmental traumatology, Part I: Biological stress systems. Biological Psychiatry, 45, 1259-1270.
32. DeYoung, C., Cicchetti, D., & Rogosch, F. A. (2011). Moderation of the association between childhood maltreatment and neuroticism by the corti- cotropin-releasing hormone receptor1 gene. Journal ofChild Psychology and Psychiatry, 52, 898-906.
33. Feder, A., Coplan, J. D., Goetz, R. R., Mathew, S. J., Pine, D. S., Dahl, R. E., et al. (2004). Twenty-four-hour cortisol secretion patterns in prepubertal children with anxiety of depressive disorders. Biological Psychiatry, 56, 198-204. (Pubitemid 38969153)
34. Felitti, V. F., Anda, R. F., Nordenberg, D., Williamson, D. F., Spitz, A. M., Edwards, V., et al. (1998). Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults: The Adverse Childhood Experiences (ACE) study. American Journal ofPre- ventive Medicine, 14, 245-258.
35. Ganzel, B., Morris, P., & Wethington, E. (2010). Allostasis and the human brain: Integrating models of stress from the social and life sciences. Psychological Review, 117, 134-174.
36. Ganzel, B. L., & Morris, P. A. (2011). Allostasis and the developing human brain: Explicit consideration of implicit models. Development and Psy-chopathology, 23, 955-974.
37. Gelernter, J., Kranzler, H., & Cubells, J. F. (1997). Serotonin transporter protein (SLC6A4) allele and haplotype frequencies and linkage disequilibria in African- and European-American and Japanese populations and in alcohol-dependent subjects. Human Genetics, 101, 243-246. (Pubitemid 28014742)
38. Grabe, H. J., Schwahn, C., Appel, K., Mahler, J., Schulz, A., Spitzer, C., et al. (2010). Childhood maltreatment, the corticotrophin-releasing hormone receptor gene and adult depression in the general population. American Journal ofMedical Genetics Part B: Neuropsychiatric Genetics, 153B, 1483-1493.
39. Granger, D. A., Schwartz, E. B., Booth, A., Curran, M., & Zakaria, D. (1999). Assessing dehydroepiandrosterone in saliva: A simple radioim- munoassay for use in studies of children, adolescents and adults. Psycho- neuroendocrinology, 24, 567-579. (Pubitemid 29268436)
40. Griffith, J. W., Uliaszek, A. A., Hauner, K. K. Y., Zinbarg, R. E., Craske, M. G., Mineka, S., et al. (2009). An examination of content overlap and disorder-specific predictions in the associations of neuroticism with anxiety and depression. Journal of Research in Personality, 43, 785-794.
41. Gunnar, M. R., & Quevedo, K. (2007). The neurobiology of stress and development. Annual Review of Psychology, 58, 145-173.
42. Gunnar, M. R., & Vazquez, D. (2006). Stress neurobiology and developmental psychopathology. In D. Cicchetti & D. Cohen (Eds.), Developmental psychopathology: Vol. 2. Developmental neuroscience (2nd ed., pp. 533-577). New York: Wiley.
43. Hariri, A., & Holmes, A. (2006). Genetics of emotional regulation: The role of the serotonin transporter in neural function. Trends in Cognitive Science, 10, 182-191.
44. Hart, J., Gunnar, M. R., & Cicchetti, D. (1996). Altered neuroendocrine activity in maltreated children related to symptoms of depression. Development and Psychopathology, 8, 201-214. (Pubitemid 126450307)
45. Heim, C., &Nemeroff, C. B. (2001). The role of childhood trauma in the neu- robiology of mood and anxiety disorders: Preclinical and clinical studies. Biological Psychiatry, 49, 1023-1039. (Pubitemid 32595461)
46. Heim, C., Newport, D. J., Mletzko, T., Miller, A. H., & Nemeroff, C. B. (2008). The link between childhood trauma and depression: Insights from HPA axis studies in humans. Psychoneuroendocrinology, 33, 693-710.
47. John, O. P., Caspi, A., Robins, R. W., Moffitt, T. E., & Stouthamer-Loeber, M. (1994). The "Little Five": Exploring the nomological network of the five-factor model of personality in adolescent boys. Child Development, 65, 160-178.
48. Juster, R.-P., Bizik, G., Picard, M., Arsenault-Lapierre, G., Sindi, S., Trepa- nier, L., et al. (2011). A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development. Development and Psychopathology, 23, 725-776.
49. Juster, R. P., McEwen, B. S., & Lupien, S. J. (2010). Allostatic load biomark- ers of chronic stress and impact on health and cognition. Neuroscience and Biobehavioral Review, 35, 2-16.
50. Kaplow, J. B., & Widom, C. S. (2007). Age of onset of child maltreatment predicts long-term mental health outcomes. Journal ofAbnormal Psychology, 116, 176-187. (Pubitemid 46328608)
51. Karg, K., Burmeister, M., Shedden, K., & Sen, S. (2011). The serotonin transporter promoter variant (5-HTTLPR), stress, and depression meta- analysis revisited. Archives ofGeneral Psychiatry, 68, 444-454.
52. Kaufman, J. (1991). Depressive disorders in maltreated children. Journal of the American Academy ofChild & Adolescent Psychiatry, 30, 257-265.
53. Kaufman, J., Birmaher, B., Perel, J., Dahl, R. E., Moreci, P., Nelson, B., etal. (1997). The corticotropic-releasing hormone challenge in depressed abused, depressed nonabused, and normal control children. Biological Psychiatry, 42, 669-679.
54. Kim-Cohen, J., Caspi, A., Taylor, A., Williams, B., Newcombe, R., Craig, I. W., et al. (2006). MAOA, maltreatment, and gene-environment interaction predicting children's mental health: New evidence and a meta-anal- ysis. Molecular Psychiatry, 11, 903-913. (Pubitemid 44470213)
55. Kovacs, M. (1982). The Children's Depression Inventory: A self-rated depression scale for school-aged youngsters. Unpublished manuscript.
56. Kovacs, M. (2004). The Children's Depression Inventory: Profile report. Unpublished manuscript.
57. Lesch, K. P., Bengel, D., Heils, A., Sabol, S. Z., Greenberg, S., Petri, S., et al. (1996). Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science, 274, 15271521.
58. Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009). Effects of stress throughout the lifespan on the brain, behavior and cognition. Nature Reviews Neuroscience, 10, 434-445.
59. Lupien, S. J., Ouellet-Morin, I., Hupbach, A., Tu, M. T., Buss, C., Walker, D., et al. (2006). Beyond the stress concept: Allostatic load-A developmental biological and cognitive perspective. In D. Cicchetti & D. Cohen (Eds.), Developmental psychopathology: Vol. 2. Developmental neu- roscience (2nd ed., pp. 578-628). New York: Wiley.
60. Manly, J. T. (2005). Invited commentary: Advances in research definitions of child maltreatment. Child Abuse and Neglect, 29, 425-439. (Pubitemid 40848384)
61. Masten, A. S., & Cicchetti, D. (2010). Developmental cascades. Development and Psychopathology, 22, 491-495.
62. McEwen, B. S. (1998). Stress, adaptation, and disease: Allostasis and allo- static load. Annals ofthe New York Academy of Sciences, 840, 33-44.
63. McEwen, B. S. (2000). Allostasis and allostatic load: Implications for neu- ropsychopharmacology. Neuropsychopharmacology, 22, 108-124. (Pubitemid 30016013)
64. McEwen, B. S., & Stellar, E. (1993). Stress and the individual mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101. (Pubitemid 23286462)
65. McEwen, B. S., & Wingfield, J. C. 2003. The conceptofallostasis in biology and biomedicine. Hormones and Behavior, 43, 2-15.
66. McGowan, P. O., & Szyf, M. (2010). The epigenetics of social adversity in early life: Implications for mental health outcomes. Neurobiology ofDis- ease, 39, 66-72.
67. Meaney, M. J. (2010). Epigenetics and the biological definition of Gene x Environment interactions. Child Development, 81, 41-79.
68. Polanczyk, G., Caspi, A., Williams, B., Price, T. S., Danese, A., Sugden, K., et al. (2009). Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: Replication and extension. Archives ofGeneral Psychiatry, 66, 978-985.
69. Pollak, S. D., Cicchetti, D., Hornung, K., & Reed, A. (2000). Recognizing emotion in faces: Developmental effects of child abuse and neglect. Developmental Psychology, 36, 679-688.
70. Pollak, S. D., Cicchetti, D., Klorman, R., & Brumaghim, J. (1997). Cognitive brain event-related potentials and emotion processing in maltreated children. Child Development, 68, 773-787.
71. Pollak, S. D., & Tolley-Schell, S. A. (2003). Selective attention to facial emotion in physically abused children. Journal of Abnormal Psychology, 112, 323-338. (Pubitemid 36959359)
72. Ressler, K. J., Bradley, B., Mercer, K. B., Deveau, T. C., Smith, A. K., Gil-lespie, C. F., et al. (2010). Polymorphisms in CRHR1 and the serotonin transporter loci: Gene x Gene x Environment interactions on depressive symptoms. American Journal ofMedical Genetics, Part B: Neuropsy- chiatric Genetics, 153B, 812-824.
73. Rieder, C., & Cicchetti, D. (1989). Organizational perspective on cognitive control functioning and cognitive-affective balance in maltreated children. Developmental Psychology, 25, 382-393.
74. Risch, N., Herrell, R., Lehner, T., Liang, K. Y., Eaves, L., Hoh, J., et al. (2009). Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: A meta-analysis. Journal of the American Medical Association, 301, 2462-2471.
75. Sanchez, M. M., Young, L. J., Plotsky, P. M., & Insel, T. R. (1999). Autora- diographic and in situ hybridization localization of corticotrophin-releas- ing factor 1 and 2 receptors in nonhuman primate brain. Journal ofCom- parative Neurology, 408, 365-377. (Pubitemid 29211189)
76. Schulkin, J. (2003). Allostasis: A neural behavioral perspective. Hormones and Behavior, 43, 21-27. (Pubitemid 36293271)
77. Sedlak, A. J., Mettenburg, J., Basena, M., Petta, I., McPherson, K., Greene, A., et al. (2010). Fourth National Incidence Study ofChild Abuse andNe- glect (NIS-4): Report to Congress. Washington, DC: US Department of Health and Human Services, Administration for Children, Youth and Families.
78. Sterling, P., & Eyer, J. (1988). Allostasis: A new paradigm to explain arousal pathology. In S. Fisher & J. Reason (Eds.), Handbook oflife stress, cognition and health ( pp. 629-649). Chichester: Wiley.
79. Susman, E. J., Dockray, S., Dorn, L. D., Schiefelbein, V. L., Herwehe, S., & Heaton, J. A. (2007). Morning/eveningness, morning-to-afternoon corti- sol ratio, and antisocial behavior problems during puberty. Developmental Psychology, 43, 811-822.
80. Tarullo, A. R., & Gunnar, M. R. (2006). Child maltreatment and the developing HPA axis. Hormones and Behavior, 50, 632-639. (Pubitemid 44307108)
81. Toth, S. L., Manly, J. T., & Cicchetti, D. (1992). Child maltreatment and vulnerability to depression. Development and Psychopathology, 4, 97-112.
82. Trickett, P. K., Noll, J. G., Susman, E. J., Shenk, C. E., & Putnam, F. W. (2010). Attenuation of cortisol across development for victims of sexual abuse. Development and Psychopathology, 22, 165-175.
83. Tyrka, A. R., Price, L. H., Gelernter, J., Schepker, C., Anderson, G. M., & Carpenter, L. L. (2009). Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: Effects on hypothala- mic-pituitary-adrenal axis reactivity. Biological Psychiatry, 66, 681685.
84. Tyrka, A. R., Price, L. H., Kao, H. T., Porter, B., Marsella, S. A., & Carpenter, L. L. (2010). Childhood maltreatment and telomere shortening: Preliminary support for an effect of early stress on cellular aging. Biological Psychiatry, 67, 531-534.
85. Warnes, G. R. (2003). The genetics package. RNews, 3, 9-13.
86. Watson, D., & Clark, L. (1984). Negative affectivity: The disposition to experience aversive emotional states. Psychological Bulletin, 96, 465490.
87. Widom, C. S., DuMont, K., & Czaja, S. J. (2007). A prospective investigation of major depressive disorder and comorbidity in abused and neglected children grow up. Archives ofGeneral Psychiatry, 64, 49-56. (Pubitemid 46041738)
88. Wilst, S., van Rossum, E. F. C., Federenko, I. S., Koper, J. W., Kumsta, R., & Hellhammer, D. H. (2004). Common polymorphisms in the glucocorti- coid receptor gene are associated with adrenocortical responses to psy- chosocial stress. Journal ofClinical Endocrinology and Metabolism, 89, 565-573. (Pubitemid 38269859)