JAK of all trades: JAK2-STAT5 as novel therapeutic targets in BCR-ABL1 + chronic myeloid leukemia

Blood

Volumn 122, Issue 13, 2013, Pages 2167-2175

  Warsch, Wolfgang ^a,c   Walz, Christoph ^b   Sexl, Veronika ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

5 CHLORO N2 [1 (5 FLUORO 2 PYRIMIDINYL)ETHYL] N4 (5 METHYL 1H PYRAZOL 3 YL) 2,4 PYRIMIDINEDIAMINE; BARICITINIB; BCR ABL PROTEIN; BCR ABL1 PROTEIN; BMS 911543; FEDRATINIB; GANDOTINIB; IMATINIB; JANUS KINASE 2; JANUS KINASE INHIBITOR; LESTAURTINIB; MOMELOTINIB; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; N TERT BUTYL 3 [5 METHYL 2 [4 (4 METHYL 1 PIPERAZINYL)PHENYLAMINO] 4 PYRIMIDINYLAMINO]BENZENESULFONAMIDE; NILOTINIB; NS 018; PACRITINIB; PROTEIN TYROSINE KINASE INHIBITOR; RUXOLITINIB; STAT3 PROTEIN; STAT5 PROTEIN; STAT5B PROTEIN; TQ 101348; UNCLASSIFIED DRUG;

APOPTOSIS; CANCER STEM CELL; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; CLINICAL TRIAL (TOPIC); DRUG TARGETING; HUMAN; INTRACELLULAR SIGNALING; LEUKEMIA CELL; LEUKEMOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; REVIEW; STEM CELL NICHE; ANIMAL; METABOLISM;

ANIMALS; HUMANS; JANUS KINASE 2; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; NEOPLASTIC STEM CELLS; STAT5 TRANSCRIPTION FACTOR;

EID: 84887392984     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-02-485573     Document Type: Review

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