-
1
-
-
49249091689
-
Is tumor growth sustained by rare cancer stem cells or dominant clones
-
Adams JM, Strasser A (2008) Is tumor growth sustained by rare cancer stem cells or dominant clones? Cancer Res 68: 4018-4021.
-
(2008)
Cancer Res
, vol.68
, pp. 4018-4021
-
-
Adams, J.M.1
Strasser, A.2
-
2
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi K, Traver D, Miyamoto T, Weissman IL (2000) A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature 404: 193-197.
-
(2000)
Nature
, vol.404
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
3
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100: 3983-3988.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
4
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K, Lutz C, van Delft FW, Bateman CM, Guo Y, Colman SM, Kempski H, Moorman AV, Titley I, Swansbury J, et al (2011) Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 469: 356-361.
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
van Delft, F.W.3
Bateman, C.M.4
Guo, Y.5
Colman, S.M.6
Kempski, H.7
Moorman, A.V.8
Titley, I.9
Swansbury, J.10
-
5
-
-
34247595838
-
Modeling the initiation and progression of human acute leukemia in mice
-
Barabe F, Kennedy JA, Hope KJ, Dick JE (2007) Modeling the initiation and progression of human acute leukemia in mice. Science 316: 600-604.
-
(2007)
Science
, vol.316
, pp. 600-604
-
-
Barabe, F.1
Kennedy, J.A.2
Hope, K.J.3
Dick, J.E.4
-
6
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D, Dick JE (1997) Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730-737.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
7
-
-
78650949272
-
Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity
-
Corbin AS, Agarwal A, Loriaux M, Cortes J, Deininger MW, Druker BJ (2011) Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity. J Clin Invest 121: 396-409.
-
(2011)
J Clin Invest
, vol.121
, pp. 396-409
-
-
Corbin, A.S.1
Agarwal, A.2
Loriaux, M.3
Cortes, J.4
Deininger, M.W.5
Druker, B.J.6
-
8
-
-
0346100567
-
Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors
-
Cozzio A, Passegue E, Ayton PM, Karsunky H, Cleary ML, Weissman IL (2003) Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev 17: 3029-3035.
-
(2003)
Genes Dev
, vol.17
, pp. 3029-3035
-
-
Cozzio, A.1
Passegue, E.2
Ayton, P.M.3
Karsunky, H.4
Cleary, M.L.5
Weissman, I.L.6
-
9
-
-
58149380742
-
Stem cell concepts renew cancer research
-
Dick JE (2008) Stem cell concepts renew cancer research. Blood 112: 4793-4807.
-
(2008)
Blood
, vol.112
, pp. 4793-4807
-
-
Dick, J.E.1
-
10
-
-
50649118068
-
Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation
-
Dierks C, Beigi R, Guo GR, Zirlik K, Stegert MR, Manley P, Trussell C, Schmitt-Graeff A, Landwerlin K, Veelken H, et al (2008) Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation. Cancer Cell 14: 238-249.
-
(2008)
Cancer Cell
, vol.14
, pp. 238-249
-
-
Dierks, C.1
Beigi, R.2
Guo, G.R.3
Zirlik, K.4
Stegert, M.R.5
Manley, P.6
Trussell, C.7
Schmitt-Graeff, A.8
Landwerlin, K.9
Veelken, H.10
-
11
-
-
32544437957
-
Initiation of pre-B cell receptor signaling: common and distinctive features in human and mouse
-
Espeli M, Rossi B, Mancini SJ, Roche P, Gauthier L, Schiff C (2006) Initiation of pre-B cell receptor signaling: common and distinctive features in human and mouse. Semin Immunol 18: 56-66.
-
(2006)
Semin Immunol
, vol.18
, pp. 56-66
-
-
Espeli, M.1
Rossi, B.2
Mancini, S.J.3
Roche, P.4
Gauthier, L.5
Schiff, C.6
-
12
-
-
0017653321
-
Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage
-
Fialkow PJ, Jacobson RJ, Papayannopoulou T (1977) Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. Am J Med 63: 125-130.
-
(1977)
Am J Med
, vol.63
, pp. 125-130
-
-
Fialkow, P.J.1
Jacobson, R.J.2
Papayannopoulou, T.3
-
13
-
-
77955121375
-
Identification of a cell of origin for human prostate cancer
-
Goldstein AS, Huang J, Guo C, Garraway IP, Witte ON (2010) Identification of a cell of origin for human prostate cancer. Science 329: 568-571.
-
(2010)
Science
, vol.329
, pp. 568-571
-
-
Goldstein, A.S.1
Huang, J.2
Guo, C.3
Garraway, I.P.4
Witte, O.N.5
-
14
-
-
84857143671
-
BCR/ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia
-
in press
-
Hantschel O, Warsch W, Eckelhart E, Kaupe I, Grebien F, Wagner KU, Superti-Furga G, Sexl V (2012) BCR/ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia. Nat Chem Biol 8, in press.
-
(2012)
Nat Chem Biol
, pp. 8
-
-
Hantschel, O.1
Warsch, W.2
Eckelhart, E.3
Kaupe, I.4
Grebien, F.5
Wagner, K.U.6
Superti-Furga, G.7
Sexl, V.8
-
15
-
-
33745111882
-
Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation
-
Hoelbl A, Kovacic B, Kerenyi MA, Simma O, Warsch W, Cui Y, Beug H, Hennighausen L, Moriggl R, Sexl V (2006) Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation. Blood 107: 4898-4906.
-
(2006)
Blood
, vol.107
, pp. 4898-4906
-
-
Hoelbl, A.1
Kovacic, B.2
Kerenyi, M.A.3
Simma, O.4
Warsch, W.5
Cui, Y.6
Beug, H.7
Hennighausen, L.8
Moriggl, R.9
Sexl, V.10
-
16
-
-
77953667590
-
Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia
-
Hoelbl A, Schuster C, Kovacic B, Zhu B, Wickre M, Hoelzl MA, Fajmann S, Grebien F, Warsch W, Stengl G, et al (2010) Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med 2: 98-110.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 98-110
-
-
Hoelbl, A.1
Schuster, C.2
Kovacic, B.3
Zhu, B.4
Wickre, M.5
Hoelzl, M.A.6
Fajmann, S.7
Grebien, F.8
Warsch, W.9
Stengl, G.10
-
17
-
-
0033568250
-
Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
-
Holyoake T, Jiang X, Eaves C, Eaves A (1999) Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia. Blood 94: 2056-2064.
-
(1999)
Blood
, vol.94
, pp. 2056-2064
-
-
Holyoake, T.1
Jiang, X.2
Eaves, C.3
Eaves, A.4
-
18
-
-
38349183668
-
Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia
-
Hong D, Gupta R, Ancliff P, Atzberger A, Brown J, Soneji S, Green J, Colman S, Piacibello W, Buckle V, et al (2008) Initiating and cancer-propagating cells in TEL-AML1-associated childhood leukemia. Science 319: 336-339.
-
(2008)
Science
, vol.319
, pp. 336-339
-
-
Hong, D.1
Gupta, R.2
Ancliff, P.3
Atzberger, A.4
Brown, J.5
Soneji, S.6
Green, J.7
Colman, S.8
Piacibello, W.9
Buckle, V.10
-
19
-
-
3242754448
-
Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
-
Hope KJ, Jin L, Dick JE (2004) Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol 5: 738-743.
-
(2004)
Nat Immunol
, vol.5
, pp. 738-743
-
-
Hope, K.J.1
Jin, L.2
Dick, J.E.3
-
20
-
-
2442465000
-
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia
-
Hu Y, Liu Y, Pelletier S, Buchdunger E, Warmuth M, Fabbro D, Hallek M, Van Etten RA, Li S (2004) Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia. Nat Genet 36: 453-461.
-
(2004)
Nat Genet
, vol.36
, pp. 453-461
-
-
Hu, Y.1
Liu, Y.2
Pelletier, S.3
Buchdunger, E.4
Warmuth, M.5
Fabbro, D.6
Hallek, M.7
Van Etten, R.A.8
Li, S.9
-
21
-
-
19944385935
-
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
-
Huntly BJ, Shigematsu H, Deguchi K, Lee BH, Mizuno S, Duclos N, Rowan R, Amaral S, Curley D, Williams IR, et al (2004) MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell 6: 587-596.
-
(2004)
Cancer Cell
, vol.6
, pp. 587-596
-
-
Huntly, B.J.1
Shigematsu, H.2
Deguchi, K.3
Lee, B.H.4
Mizuno, S.5
Duclos, N.6
Rowan, R.7
Amaral, S.8
Curley, D.9
Williams, I.R.10
-
22
-
-
0042190662
-
Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias
-
Jaiswal S, Traver D, Miyamoto T, Akashi K, Lagasse E, Weissman IL (2003) Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias. Proc Natl Acad Sci USA 100: 10002-10007.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10002-10007
-
-
Jaiswal, S.1
Traver, D.2
Miyamoto, T.3
Akashi, K.4
Lagasse, E.5
Weissman, I.L.6
-
23
-
-
3943088431
-
Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML
-
Jamieson CH, Ailles LE, Dylla SJ, Muijtjens M, Jones C, Zehnder JL, Gotlib J, Li K, Manz MG, Keating A, et al (2004) Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. N Engl J Med 351: 657-667.
-
(2004)
N Engl J Med
, vol.351
, pp. 657-667
-
-
Jamieson, C.H.1
Ailles, L.E.2
Dylla, S.J.3
Muijtjens, M.4
Jones, C.5
Zehnder, J.L.6
Gotlib, J.7
Li, K.8
Manz, M.G.9
Keating, A.10
-
24
-
-
34547113747
-
Tumor growth need not be driven by rare cancer stem cells
-
Kelly PN, Dakic A, Adams JM, Nutt SL, Strasser A (2007) Tumor growth need not be driven by rare cancer stem cells. Science 317: 337.
-
(2007)
Science
, vol.317
, pp. 337
-
-
Kelly, P.N.1
Dakic, A.2
Adams, J.M.3
Nutt, S.L.4
Strasser, A.5
-
25
-
-
33745965645
-
Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors
-
Kim I, He S, Yilmaz OH, Kiel MJ, Morrison SJ (2006) Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood 108: 737-744.
-
(2006)
Blood
, vol.108
, pp. 737-744
-
-
Kim, I.1
He, S.2
Yilmaz, O.H.3
Kiel, M.J.4
Morrison, S.J.5
-
26
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo M, Weissman IL, Akashi K (1997) Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 91: 661-672.
-
(1997)
Cell
, vol.91
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
27
-
-
0022182626
-
Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products
-
Konopka JB, Witte ON (1985) Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products. Mol Cell Biol 5: 3116-3123.
-
(1985)
Mol Cell Biol
, vol.5
, pp. 3116-3123
-
-
Konopka, J.B.1
Witte, O.N.2
-
28
-
-
33746498580
-
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9
-
Krivtsov AV, Twomey D, Feng Z, Stubbs MC, Wang Y, Faber J, Levine JE, Wang J, Hahn WC, Gilliland DG, et al (2006) Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9. Nature 442: 818-822.
-
(2006)
Nature
, vol.442
, pp. 818-822
-
-
Krivtsov, A.V.1
Twomey, D.2
Feng, Z.3
Stubbs, M.C.4
Wang, Y.5
Faber, J.6
Levine, J.E.7
Wang, J.8
Hahn, W.C.9
Gilliland, D.G.10
-
29
-
-
0028091194
-
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
-
Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, Minden M, Paterson B, Caligiuri MA, Dick JE (1994) A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 367: 645-648.
-
(1994)
Nature
, vol.367
, pp. 645-648
-
-
Lapidot, T.1
Sirard, C.2
Vormoor, J.3
Murdoch, B.4
Hoang, T.5
Caceres-Cortes, J.6
Minden, M.7
Paterson, B.8
Caligiuri, M.A.9
Dick, J.E.10
-
30
-
-
0033519238
-
The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity
-
Li S, Ilaria RL, Jr, Million RP, Daley GQ, Van Etten RA (1999) The P190, P210, and P230 forms of the BCR/ABL oncogene induce a similar chronic myeloid leukemia-like syndrome in mice but have different lymphoid leukemogenic activity. J Exp Med 189: 1399-1412.
-
(1999)
J Exp Med
, vol.189
, pp. 1399-1412
-
-
Li, S.1
Ilaria Jr., R.L.2
Million, R.P.3
Daley, G.Q.4
Van Etten, R.A.5
-
31
-
-
0029816460
-
The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype
-
Melo JV (1996) The diversity of BCR-ABL fusion proteins and their relationship to leukemia phenotype. Blood 88: 2375-2384.
-
(1996)
Blood
, vol.88
, pp. 2375-2384
-
-
Melo, J.V.1
-
32
-
-
19944431828
-
Stat5 tetramer formation is associated with leukemogenesis
-
Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, Hoffmeyer A, Bauer A, Piekorz R, Wang D, et al (2005) Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell 7: 87-99.
-
(2005)
Cancer Cell
, vol.7
, pp. 87-99
-
-
Moriggl, R.1
Sexl, V.2
Kenner, L.3
Duntsch, C.4
Stangl, K.5
Gingras, S.6
Hoffmeyer, A.7
Bauer, A.8
Piekorz, R.9
Wang, D.10
-
33
-
-
34948839961
-
Leukemia stem cells in a genetically defined murine model of blast-crisis CML
-
Neering SJ, Bushnell T, Sozer S, Ashton J, Rossi RM, Wang PY, Bell DR, Heinrich D, Bottaro A, Jordan CT (2007) Leukemia stem cells in a genetically defined murine model of blast-crisis CML. Blood 110: 2578-2585.
-
(2007)
Blood
, vol.110
, pp. 2578-2585
-
-
Neering, S.J.1
Bushnell, T.2
Sozer, S.3
Ashton, J.4
Rossi, R.M.5
Wang, P.Y.6
Bell, D.R.7
Heinrich, D.8
Bottaro, A.9
Jordan, C.T.10
-
34
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F, Mullighan CG, Wang JC, Poeppl A, Doulatov S, Phillips LA, Ma J, Minden MD, Downing JR, Dick JE (2011) Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 469: 362-367.
-
(2011)
Nature
, vol.469
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.3
Poeppl, A.4
Doulatov, S.5
Phillips, L.A.6
Ma, J.7
Minden, M.D.8
Downing, J.R.9
Dick, J.E.10
-
35
-
-
72849159485
-
Chromosome studies on normal and leukemic human leukocytes
-
Nowell PC, Hungerford DA (1960) Chromosome studies on normal and leukemic human leukocytes. J Natl Cancer Inst 25: 85-109.
-
(1960)
J Natl Cancer Inst
, vol.25
, pp. 85-109
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
36
-
-
67651166902
-
Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder
-
Oravecz-Wilson KI, Philips ST, Yilmaz OH, Ames HM, Li L, Crawford BD, Gauvin AM, Lucas PC, Sitwala K, Downing JR, et al (2009) Persistence of leukemia-initiating cells in a conditional knockin model of an imatinib-responsive myeloproliferative disorder. Cancer Cell 16: 137-148.
-
(2009)
Cancer Cell
, vol.16
, pp. 137-148
-
-
Oravecz-Wilson, K.I.1
Philips, S.T.2
Yilmaz, O.H.3
Ames, H.M.4
Li, L.5
Crawford, B.D.6
Gauvin, A.M.7
Lucas, P.C.8
Sitwala, K.9
Downing, J.R.10
-
37
-
-
7044269527
-
JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells
-
Passegue E, Wagner EF, Weissman IL (2004) JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells. Cell 119: 431-443.
-
(2004)
Cell
, vol.119
, pp. 431-443
-
-
Passegue, E.1
Wagner, E.F.2
Weissman, I.L.3
-
38
-
-
58149333204
-
Cancer induction by restriction of oncogene expression to the stem cell compartment
-
Perez-Caro M, Cobaleda C, Gonzalez-Herrero I, Vicente-Duenas C, Bermejo-Rodriguez C, Sanchez-Beato M, Orfao A, Pintado B, Flores T, Sanchez-Martin M, et al (2009) Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO J 28: 8-20.
-
(2009)
EMBO J
, vol.28
, pp. 8-20
-
-
Perez-Caro, M.1
Cobaleda, C.2
Gonzalez-Herrero, I.3
Vicente-Duenas, C.4
Bermejo-Rodriguez, C.5
Sanchez-Beato, M.6
Orfao, A.7
Pintado, B.8
Flores, T.9
Sanchez-Martin, M.10
-
39
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ (2008) Efficient tumour formation by single human melanoma cells. Nature 456: 593-598.
-
(2008)
Nature
, vol.456
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
40
-
-
78249250559
-
Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized
-
Quintana E, Shackleton M, Foster HR, Fullen DR, Sabel MS, Johnson TM, Morrison SJ (2010) Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized. Cancer Cell 18: 510-523.
-
(2010)
Cancer Cell
, vol.18
, pp. 510-523
-
-
Quintana, E.1
Shackleton, M.2
Foster, H.R.3
Fullen, D.R.4
Sabel, M.S.5
Johnson, T.M.6
Morrison, S.J.7
-
41
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, Peschle C, De Maria R (2007) Identification and expansion of human colon-cancer-initiating cells. Nature 445: 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
42
-
-
79959854279
-
Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease
-
Risueno RM, Campbell CJ, Dingwall S, Levadoux-Martin M, Leber B, Xenocostas A, Bhatia M (2011) Identification of T-lymphocytic leukemia-initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease. Blood 117: 7112-7120.
-
(2011)
Blood
, vol.117
, pp. 7112-7120
-
-
Risueno, R.M.1
Campbell, C.J.2
Dingwall, S.3
Levadoux-Martin, M.4
Leber, B.5
Xenocostas, A.6
Bhatia, M.7
-
43
-
-
0035166003
-
The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase
-
Roumiantsev S, de Aos IE, Varticovski L, Ilaria RL, Van Etten RA (2001) The src homology 2 domain of Bcr/Abl is required for efficient induction of chronic myeloid leukemia-like disease in mice but not for lymphoid leukemogenesis or activation of phosphatidylinositol 3-kinase. Blood 97: 4-13.
-
(2001)
Blood
, vol.97
, pp. 4-13
-
-
Roumiantsev, S.1
de Aos, I.E.2
Varticovski, L.3
Ilaria, R.L.4
Van Etten, R.A.5
-
44
-
-
0015694748
-
Letter: a new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
-
Rowley JD (1973) Letter: a new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 243: 290-293.
-
(1973)
Nature
, vol.243
, pp. 290-293
-
-
Rowley, J.D.1
-
45
-
-
70450265398
-
A robust xenotransplantation model for acute myeloid leukemia
-
Sanchez PV, Perry RL, Sarry JE, Perl AE, Murphy K, Swider CR, Bagg A, Choi JK, Biegel JA, Danet-Desnoyers G, et al (2009) A robust xenotransplantation model for acute myeloid leukemia. Leukemia 23: 2109-2117.
-
(2009)
Leukemia
, vol.23
, pp. 2109-2117
-
-
Sanchez, P.V.1
Perry, R.L.2
Sarry, J.E.3
Perl, A.E.4
Murphy, K.5
Swider, C.R.6
Bagg, A.7
Choi, J.K.8
Biegel, J.A.9
Danet-Desnoyers, G.10
-
46
-
-
0034665676
-
Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5
-
Sexl V, Piekorz R, Moriggl R, Rohrer J, Brown MP, Bunting KD, Rothammer K, Roussel MF, Ihle JN (2000) Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. Blood 96: 2277-2283.
-
(2000)
Blood
, vol.96
, pp. 2277-2283
-
-
Sexl, V.1
Piekorz, R.2
Moriggl, R.3
Rohrer, J.4
Brown, M.P.5
Bunting, K.D.6
Rothammer, K.7
Roussel, M.F.8
Ihle, J.N.9
-
47
-
-
69449096005
-
Heterogeneity in cancer: cancer stem cells versus clonal evolution
-
Shackleton M, Quintana E, Fearon ER, Morrison SJ (2009) Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 138: 822-829.
-
(2009)
Cell
, vol.138
, pp. 822-829
-
-
Shackleton, M.1
Quintana, E.2
Fearon, E.R.3
Morrison, S.J.4
-
48
-
-
79960414811
-
IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias
-
Silva A, Laranjeira AB, Martins LR, Cardoso BA, Demengeot J, Yunes JA, Seddon B, Barata JT (2011) IL-7 contributes to the progression of human T-cell acute lymphoblastic leukemias. Cancer Res 71: 4780-4789.
-
(2011)
Cancer Res
, vol.71
, pp. 4780-4789
-
-
Silva, A.1
Laranjeira, A.B.2
Martins, L.R.3
Cardoso, B.A.4
Demengeot, J.5
Yunes, J.A.6
Seddon, B.7
Barata, J.T.8
-
49
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB (2004) Identification of human brain tumour initiating cells. Nature 432: 396-401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
50
-
-
0042872887
-
MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice
-
So CW, Karsunky H, Passegue E, Cozzio A, Weissman IL, Cleary ML (2003) MLL-GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice. Cancer Cell 3: 161-171.
-
(2003)
Cancer Cell
, vol.3
, pp. 161-171
-
-
So, C.W.1
Karsunky, H.2
Passegue, E.3
Cozzio, A.4
Weissman, I.L.5
Cleary, M.L.6
-
51
-
-
33749440584
-
Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia
-
Somervaille TC, Cleary ML (2006) Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. Cancer Cell 10: 257-268.
-
(2006)
Cancer Cell
, vol.10
, pp. 257-268
-
-
Somervaille, T.C.1
Cleary, M.L.2
-
52
-
-
50949090415
-
Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells
-
Taussig DC, Miraki-Moud F, Anjos-Afonso F, Pearce DJ, Allen K, Ridler C, Lillington D, Oakervee H, Cavenagh J, Agrawal SG, et al (2008) Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells. Blood 112: 568-575.
-
(2008)
Blood
, vol.112
, pp. 568-575
-
-
Taussig, D.C.1
Miraki-Moud, F.2
Anjos-Afonso, F.3
Pearce, D.J.4
Allen, K.5
Ridler, C.6
Lillington, D.7
Oakervee, H.8
Cavenagh, J.9
Agrawal, S.G.10
-
53
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE (2011) Cells of origin in cancer. Nature 469: 314-322.
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
54
-
-
65949110140
-
Malignant stem cells in childhood acute lymphoblastic leukemia: the stem cell concept revisited
-
Vormoor HJ (2009) Malignant stem cells in childhood acute lymphoblastic leukemia: the stem cell concept revisited. Cell Cycle 8: 996-999.
-
(2009)
Cell Cycle
, vol.8
, pp. 996-999
-
-
Vormoor, H.J.1
-
55
-
-
24344506258
-
Cancer stem cells: lessons from leukemia
-
Wang JC, Dick JE (2005) Cancer stem cells: lessons from leukemia. Trends Cell Biol 15: 494-501.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 494-501
-
-
Wang, J.C.1
Dick, J.E.2
-
56
-
-
58149176136
-
The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene
-
Wang PY, Young F, Chen CY, Stevens BM, Neering SJ, Rossi RM, Bushnell T, Kuzin I, Heinrich D, Bottaro A, et al (2008) The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene. Blood 112: 4184-4192.
-
(2008)
Blood
, vol.112
, pp. 4184-4192
-
-
Wang, P.Y.1
Young, F.2
Chen, C.Y.3
Stevens, B.M.4
Neering, S.J.5
Rossi, R.M.6
Bushnell, T.7
Kuzin, I.8
Heinrich, D.9
Bottaro, A.10
-
57
-
-
33646248661
-
Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia
-
Williams RT, Roussel MF, Sherr CJ (2006) Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia. Proc Natl Acad Sci USA 103: 6688-6693.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6688-6693
-
-
Williams, R.T.1
Roussel, M.F.2
Sherr, C.J.3
-
58
-
-
34548841964
-
Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia
-
Williams RT, den Besten W, Sherr CJ (2007) Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia. Genes Dev 21: 2283-2287.
-
(2007)
Genes Dev
, vol.21
, pp. 2283-2287
-
-
Williams, R.T.1
den Besten, W.2
Sherr, C.J.3
-
59
-
-
80053385665
-
Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia
-
Zenatti PP, Ribeiro D, Li W, Zuurbier L, Silva MC, Paganin M, Tritapoe J, Hixon JA, Silveira AB, Cardoso BA, et al (2011) Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia. Nat Genet 43: 932-939.
-
(2011)
Nat Genet
, vol.43
, pp. 932-939
-
-
Zenatti, P.P.1
Ribeiro, D.2
Li, W.3
Zuurbier, L.4
Silva, M.C.5
Paganin, M.6
Tritapoe, J.7
Hixon, J.A.8
Silveira, A.B.9
Cardoso, B.A.10
-
60
-
-
19444386119
-
Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion
-
Zhang CC, Lodish HF (2005) Murine hematopoietic stem cells change their surface phenotype during ex vivo expansion. Blood 105: 4314-4320.
-
(2005)
Blood
, vol.105
, pp. 4314-4320
-
-
Zhang, C.C.1
Lodish, H.F.2
-
61
-
-
47149088471
-
Cytokines regulating hematopoietic stem cell function
-
Zhang CC, Lodish HF (2008) Cytokines regulating hematopoietic stem cell function. Curr Opin Hematol 15: 307-311.
-
(2008)
Curr Opin Hematol
, vol.15
, pp. 307-311
-
-
Zhang, C.C.1
Lodish, H.F.2
|