-
1
-
-
33746153978
-
CML: Molecular mechanisms and therapeutic strategies
-
Arlinghaus RB, invited guest editor
-
Arlinghaus RB, invited guest editor. CML: molecular mechanisms and therapeutic strategies. Oncogene (Review) 2002;31:8560-7.
-
(2002)
Oncogene (Review)
, vol.31
, pp. 8560-8567
-
-
-
2
-
-
0035959746
-
Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation
-
Xie S, Wang Y, Liu J, et al. Involvement of Jak2 tyrosine phosphorylation in Bcr-Abl transformation. Oncogene 2001;20:6188-95.
-
(2001)
Oncogene
, vol.20
, pp. 6188-6195
-
-
Xie, S.1
Wang, Y.2
Liu, J.3
-
3
-
-
0036847027
-
The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells
-
Klejman A, Schreiner SJ, Nieborowska-Skorska M, et al. The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells. EMBO J 2002;21:5766-74.
-
(2002)
EMBO J
, vol.21
, pp. 5766-5774
-
-
Klejman, A.1
Schreiner, S.J.2
Nieborowska-Skorska, M.3
-
4
-
-
0037222235
-
Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: High incidence of early complete and major cytogenetic responses
-
Kantarjian HM, Cortes JE, O'Brien S, et al. Imatinib mesylate therapy in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia: high incidence of early complete and major cytogenetic responses. Blood 2003;101:97-100.
-
(2003)
Blood
, vol.101
, pp. 97-100
-
-
Kantarjian, H.M.1
Cortes, J.E.2
O'Brien, S.3
-
5
-
-
0037126385
-
Jak2 is involved in c-Myc induction by Bcr-Abl
-
Xie S, Lin H, Sun T, Arlinghaus RB. Jak2 is involved in c-Myc induction by Bcr-Abl. Oncogene 2002;21:7137-46.
-
(2002)
Oncogene
, vol.21
, pp. 7137-7146
-
-
Xie, S.1
Lin, H.2
Sun, T.3
Arlinghaus, R.B.4
-
6
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan N, Grunberger T, Dadi H, et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature 1996;379:645-8.
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
-
7
-
-
0035157978
-
The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome
-
Miyamoto N, Sugita K, Goi K, et al. The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome. Leukemia 2001;15:1758-68.
-
(2001)
Leukemia
, vol.15
, pp. 1758-1768
-
-
Miyamoto, N.1
Sugita, K.2
Goi, K.3
-
8
-
-
0033583530
-
Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis
-
Nieborowska-Skorska M, Wasik MA, Slupianek A, et al. Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis. J Exp Med 1999;189:1229-42.
-
(1999)
J Exp Med
, vol.189
, pp. 1229-1242
-
-
Nieborowska-Skorska, M.1
Wasik, M.A.2
Slupianek, A.3
-
9
-
-
0026788001
-
Dominant negative MYC blocks transformation by ABL oncogenes
-
Sawyers CL, Callahan W, Witte ON. Dominant negative MYC blocks transformation by ABL oncogenes. Cell 1992;70:901-10.
-
(1992)
Cell
, vol.70
, pp. 901-910
-
-
Sawyers, C.L.1
Callahan, W.2
Witte, O.N.3
-
10
-
-
1542289967
-
Overexpression of MEKK3 confers resistance to apoptosis through activation of NFκB
-
Samanta AK, Huang HJ, Bast RC, Jr., Liao WS. Overexpression of MEKK3 confers resistance to apoptosis through activation of NFκB. J Biol Chem 2004;279:7576-83.
-
(2004)
J Biol Chem
, vol.279
, pp. 7576-7583
-
-
Samanta, A.K.1
Huang, H.J.2
Bast Jr., R.C.3
Liao, W.S.4
-
11
-
-
19044372472
-
Critical role for Gab2 in transformation by BCR/ABL
-
Sattler M, Mohi MG, Pride YB, et al. Critical role for Gab2 in transformation by BCR/ABL. Cancer Cell 2002;1:479-92.
-
(2002)
Cancer Cell
, vol.1
, pp. 479-492
-
-
Sattler, M.1
Mohi, M.G.2
Pride, Y.B.3
-
12
-
-
24344452505
-
Phosphatidylinositol 3-kinase p85{α} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: Molecular mechanisms and biological consequences
-
Ren SY, Bolton E, Mohi MG, Morrione A, Neel BG, Skorski T. Phosphatidylinositol 3-kinase p85{α} subunit-dependent interaction with BCR/ABL-related fusion tyrosine kinases: molecular mechanisms and biological consequences. Mol Cell Biol 2005;25:8001-8.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8001-8008
-
-
Ren, S.Y.1
Bolton, E.2
Mohi, M.G.3
Morrione, A.4
Neel, B.G.5
Skorski, T.6
-
13
-
-
26244439049
-
Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase
-
Ren SY, Xue F, Feng J, Skorski T. Intrinsic regulation of the interactions between the SH3 domain of p85 subunit of phosphatidylinositol-3 kinase and the protein network of BCR/ABL oncogenic tyrosine kinase. Exp Hematol 2005;33:1222-8.
-
(2005)
Exp Hematol
, vol.33
, pp. 1222-1228
-
-
Ren, S.Y.1
Xue, F.2
Feng, J.3
Skorski, T.4
-
15
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science 2001;293:876-80.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
16
-
-
15444339209
-
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
-
Lacronique V, Boureux A, Valle VD, et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science 1997;278:1309-12.
-
(1997)
Science
, vol.278
, pp. 1309-1312
-
-
Lacronique, V.1
Boureux, A.2
Valle, V.D.3
-
17
-
-
25844469587
-
BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia
-
Griesinger F, Hennig H, Hillmer F, et al. BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia. Genes Chromosomes Cancer 2005;44:329-33.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 329-333
-
-
Griesinger, F.1
Hennig, H.2
Hillmer, F.3
-
18
-
-
27944481825
-
The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene
-
Bousquet M, Quelen C, De Mas V, et al. The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene. Oncogene 2005;24:7248-52.
-
(2005)
Oncogene
, vol.24
, pp. 7248-7252
-
-
Bousquet, M.1
Quelen, C.2
De Mas, V.3
-
19
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005;352:1779-90.
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
-
20
-
-
0035980056
-
TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3′-kinase/protein kinase B signaling pathway
-
Nguyen MH, Ho JM, Beattie BK, Barber DL. TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3′-kinase/protein kinase B signaling pathway. J Biol Chem 2001;276:32704-13.
-
(2001)
J Biol Chem
, vol.276
, pp. 32704-32713
-
-
Nguyen, M.H.1
Ho, J.M.2
Beattie, B.K.3
Barber, D.L.4
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