-
1
-
-
0038682002
-
Mechanisms of tgf-beta signaling from cell membrane to the nucleus
-
Shi Y, Massagué J. Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell. 2003;113(6):685-700.
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 685-700
-
-
Shi, Y.1
Massagué, J.2
-
2
-
-
44049087148
-
A critical function for tgf-beta signaling in the development of natural cd41cd251 foxp31 regulatory t cells
-
Liu Y, Zhang P, Li J, Kulkarni AB, Perruche S, Chen W. A critical function for TGF-beta signaling in the development of natural CD41CD251 Foxp31 regulatory T cells. Nat Immunol. 2008; 9(6):632-640.
-
(2008)
Nat Immunol
, vol.9
, Issue.6
, pp. 632-640
-
-
Liu, Y.1
Zhang, P.2
Li, J.3
Kulkarni, A.B.4
Perruche, S.5
Chen, W.6
-
3
-
-
33748448717
-
Transforming growth factor-beta controls development, homeostasis, and tolerance of t cells by regulatory t cell-dependent and -independent mechanisms
-
Li MO, Sanjabi S, Flavell RA. Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity. 2006;25(3):455-471.
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 455-471
-
-
Li, M.O.1
Sanjabi, S.2
Flavell, R.A.3
-
4
-
-
33748465396
-
Cellular mechanisms of fatal early-onset autoimmunity in mice with the t cell-specific targeting of transforming growth factor-beta receptor
-
Marie JC, Liggitt D, Rudensky AY. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity. 2006;25(3):441-454.
-
(2006)
Immunity
, vol.25
, Issue.3
, pp. 441-454
-
-
Marie, J.C.1
Liggitt, D.2
Rudensky, A.Y.3
-
5
-
-
78650309487
-
Control of the differentiation of regulatory t cells and t(h)17 cells by the dna-binding inhibitor id3
-
Maruyama T, Li J, Vaque JP, et al. Control of the differentiation of regulatory T cells and T(H)17 cells by the DNA-binding inhibitor Id3. Nat Immunol. 2011;12(1):86-95.
-
(2011)
Nat Immunol.
, vol.12
, Issue.1
, pp. 86-95
-
-
Maruyama, T.1
Li, J.2
Vaque, J.P.3
-
6
-
-
43449135305
-
Tgf-beta-induced foxp3 inhibits t(h)17 cell differentiation by antagonizing rorgammat function
-
Zhou L, Lopes JE, Chong MM, et al. TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Nature. 2008;453(7192):236-240.
-
(2008)
Nature
, vol.453
, Issue.7192
, pp. 236-240
-
-
Zhou, L.1
Lopes, J.E.2
Chong, M.M.3
-
7
-
-
0038682011
-
Parp goes transcription
-
Kraus WL, Lis JT. PARP goes transcription. Cell. 2003;113(6):677-683.
-
(2003)
Cell
, vol.113
, Issue.6
, pp. 677-683
-
-
Kraus, W.L.1
Lis, J.T.2
-
8
-
-
0033520969
-
Quality control by dna repair
-
Lindahl T, Wood RD. Quality control by DNA repair. Science. 1999;286(5446):1897-1905.
-
(1999)
Science
, vol.286
, Issue.5446
, pp. 1897-1905
-
-
Lindahl, T.1
Wood, R.D.2
-
9
-
-
0028922462
-
Mice lacking adprt and poly(adp-ribosyl)ation develop normally but are susceptible to skin disease
-
Wang ZQ, Auer B, Stingl L, et al. Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease. Genes Dev. 1995;9(5):509-520.
-
(1995)
Genes Dev.
, vol.9
, Issue.5
, pp. 509-520
-
-
Wang, Z.Q.1
Auer, B.2
Stingl, L.3
-
10
-
-
0242496900
-
Transcriptional coactivation of nuclear factor-kappab-dependent gene expression by p300 is regulated by poly(adp)-ribose polymerase-1
-
Hassa PO, Buerki C, Lombardi C, Imhof R, Hottiger MO. Transcriptional coactivation of nuclear factor-kappaB-dependent gene expression by p300 is regulated by poly(ADP)-ribose polymerase-1. J Biol Chem. 2003;278(46): 45145-45153.
-
(2003)
J Biol Chem.
, vol.278
, Issue.46
, pp. 45145-45153
-
-
Hassa, P.O.1
Buerki, C.2
Lombardi, C.3
Imhof, R.4
Hottiger, M.O.5
-
11
-
-
73149115486
-
Aire’s partners in the molecular control of immunological tolerance
-
Abramson J, Giraud M, Benoist C, Mathis D. Aire’s partners in the molecular control of immunological tolerance. Cell. 2010;140(1): 123-135.
-
(2010)
Cell
, vol.140
, Issue.1
, pp. 123-135
-
-
Abramson, J.1
Giraud, M.2
Benoist, C.3
Mathis, D.4
-
12
-
-
0033011114
-
Mice lacking the poly(adp-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin
-
Burkart V, Wang ZQ, Radons J, et al. Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. Nat Med. 1999;5(3):314-319.
-
(1999)
Nat Med.
, vol.5
, Issue.3
, pp. 314-319
-
-
Burkart, V.1
Wang, Z.Q.2
Radons, J.3
-
13
-
-
0030842946
-
Poly (adp-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
-
Eliasson MJ, Sampei K, Mandir AS, et al. Poly (ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med. 1997;3(10):1089-1095.
-
(1997)
Nat Med
, vol.3
, Issue.10
, pp. 1089-1095
-
-
Eliasson, M.J.1
Sampei, K.2
Mandir, A.S.3
-
14
-
-
69049084375
-
Toll-like receptor 2 and poly(adp-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive Eae
-
Farez MF, Quintana FJ, Gandhi R, Izquierdo G, Lucas M, Weiner HL. Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE. Nat Immunol. 2009;10(9): 958-964.
-
(2009)
Nat Immunol
, vol.10
, Issue.9
, pp. 958-964
-
-
Farez, M.F.1
Quintana, F.J.2
Gandhi, R.3
Izquierdo, G.4
Lucas, M.5
Weiner, H.L.6
-
15
-
-
0035136240
-
Diabetic endothelial dysfunction: The role of poly(adp-ribose) polymerase activation
-
Virág L, Jagtap P, Szabó E, et al; Garcia Soriano F. Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001;7(1):108-113.
-
(2001)
Nat Med.
, vol.7
, Issue.1
, pp. 108-113
-
-
Virág, L.1
Jagtap, P.2
Szabó, E.3
Garcia Soriano, F.4
-
16
-
-
70350005154
-
Parp-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis
-
Selvaraj V, Soundarapandian MM, Chechneva O, et al. PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis. J Biol Chem. 2009;284(38):26070-26084.
-
(2009)
J Biol Chem.
, vol.284
, Issue.38
, pp. 26070-26084
-
-
Selvaraj, V.1
Soundarapandian, M.M.2
Chechneva, O.3
-
17
-
-
9644295773
-
Noncleavable poly(adp-ribose) polymerase-1 regulates the inflammation response in mice
-
Pétrilli V, Herceg Z, Hassa PO, et al. Noncleavable poly(ADP-ribose) polymerase-1 regulates the inflammation response in mice. J Clin Invest. 2004;114(8):1072-1081.
-
(2004)
J Clin Invest
, vol.114
, Issue.8
, pp. 1072-1081
-
-
Pétrilli, V.1
Herceg, Z.2
Hassa, P.O.3
-
18
-
-
0348223787
-
Conversion of peripheral cd41cd25- naive t cells to cd41 cd251 regulatory t cells by tgf-beta induction of transcription factor foxp3
-
Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD41CD25- naive T cells to CD41 CD251 regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med. 2003; 198(12):1875-1886.
-
(2003)
J Exp Med
, vol.198
, Issue.12
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
-
19
-
-
77950349016
-
Th17 and regulatory t cells in mediating and restraining inflammation
-
Littman DR, Rudensky AY. Th17 and regulatory T cells in mediating and restraining inflammation. Cell. 2010;140(6):845-858.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 845-858
-
-
Littman, D.R.1
Rudensky, A.Y.2
-
20
-
-
77951634464
-
Increased foxp31 regulatory t cells in poly(adp-ribose) polymerase-1 deficiency
-
Nasta F, Laudisi F, Sambucci M, Rosado MM, Pioli C. Increased Foxp31 regulatory T cells in poly(ADP-ribose) polymerase-1 deficiency. J Immunol. 2010;184(7):3470-3477.
-
(2010)
J Immunol.
, vol.184
, Issue.7
, pp. 3470-3477
-
-
Nasta, F.1
Laudisi, F.2
Sambucci, M.3
Rosado, M.M.4
Pioli, C.5
-
21
-
-
34547788180
-
A functionally specialized population of mucosal cd1031 dcs induces foxp31 regulatory t cells via a tgf-beta and retinoic acid-dependent mechanism
-
Coombes JL, Siddiqui KR, Arancibia-Cárcamo CV, et al. A functionally specialized population of mucosal CD1031 DCs induces Foxp31 regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J Exp Med. 2007; 204(8):1757-1764.
-
(2007)
J Exp Med
, vol.204
, Issue.8
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Cárcamo, C.V.3
-
22
-
-
34547757390
-
Small intestine lamina propria dendritic cells promote de novo generation of foxp3 t reg cells via retinoic acid
-
Sun CM, Hall JA, Blank RB, et al. Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med. 2007;204(8):1775-1785.
-
(2007)
J Exp Med.
, vol.204
, Issue.8
, pp. 1775-1785
-
-
Sun, C.M.1
Hall, J.A.2
Blank, R.B.3
-
23
-
-
80755175886
-
Balancing acts: The role of tgf-b in the mucosal immune system
-
Konkel JE, Chen W. Balancing acts: the role of TGF-b in the mucosal immune system. Trends Mol Med. 2011;17(11):668-676.
-
(2011)
Trends Mol Med
, vol.17
, Issue.11
, pp. 668-676
-
-
Konkel, J.E.1
Chen, W.2
-
24
-
-
0034124755
-
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (adp-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock
-
McDonald MC, Mota-Filipe H, Wright JA, et al. Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock. Br J Pharmacol. 2000;130(4):843-850.
-
(2000)
Br J Pharmacol
, vol.130
, Issue.4
, pp. 843-850
-
-
McDonald, M.C.1
Mota-Filipe, H.2
Wright, J.A.3
-
25
-
-
71749094333
-
Development of foxp3(1) regulatory t cells is driven by the c-rel enhanceosome
-
Ruan Q, Kameswaran V, Tone Y, et al. Development of Foxp3(1) regulatory T cells is driven by the c-Rel enhanceosome. Immunity. 2009;31(6):932-940.
-
(2009)
Immunity
, vol.31
, Issue.6
, pp. 932-940
-
-
Ruan, Q.1
Kameswaran, V.2
Tone, Y.3
-
26
-
-
77955498891
-
Smad2 and smad3 are redundantly essential for the tgf-beta-mediated regulation of regulatory t plasticity and th1 development
-
published correction appears in J Immunol. 2011;186(1): 632
-
Takimoto T, Wakabayashi Y, Sekiya T, et al. Smad2 and Smad3 are redundantly essential for the TGF-beta-mediated regulation of regulatory T plasticity and Th1 development [published correction appears in J Immunol. 2011;186(1): 632]. J Immunol. 2010;185(2):842-855.
-
(2010)
J Immunol
, vol.185
, Issue.2
, pp. 842-855
-
-
Takimoto, T.1
Wakabayashi, Y.2
Sekiya, T.3
-
27
-
-
38349095578
-
Smad3 and nfat cooperate to induce foxp3 expression through its enhancer
-
Tone Y, Furuuchi K, Kojima Y, Tykocinski ML, Greene MI, Tone M. Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer. Nat Immunol. 2008;9(2):194-202.
-
(2008)
Nat Immunol
, vol.9
, Issue.2
, pp. 194-202
-
-
Tone, Y.1
Furuuchi, K.2
Kojima, Y.3
Tykocinski, M.L.4
Greene, M.I.5
Tone, M.6
-
28
-
-
78649294528
-
Parp-1 attenuates smad-mediated transcription
-
Lönn P, van der Heide LP, Dahl M, Hellman U, Heldin CH, Moustakas A. PARP-1 attenuates Smad-mediated transcription. Mol Cell. 2010; 40(4):521-532.
-
(2010)
Mol Cell
, vol.40
, Issue.4
, pp. 521-532
-
-
Lönn, P.1
Van Der Heide, L.P.2
Dahl, M.3
Hellman, U.4
Heldin, C.H.5
Moustakas, A.6
-
29
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector th17 and regulatory t cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature. 2006;441(7090):235-238.
-
(2006)
Nature
, vol.441
, Issue.7090
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
30
-
-
33646560950
-
Transforming growth factor-beta induces development of the t(h)17 lineage
-
Mangan PR, Harrington LE, O’Quinn DB, et al. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature. 2006; 441(7090):231-234.
-
(2006)
Nature
, vol.441
, Issue.7090
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O’Quinn, D.B.3
-
31
-
-
32244442562
-
Tgfbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of il-17-producing t cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 2006;24(2):179-189.
-
(2006)
Immunity
, vol.24
, Issue.2
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
32
-
-
36549005035
-
Endogenous tgf-beta activation by reactive oxygen species is key to foxp3 induction in tcr-stimulated and hiv-1-infected human cd41 cd25- t cells
-
Amarnath S, Dong L, Li J, Wu Y, Chen W. Endogenous TGF-beta activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD41 CD25- T cells. Retrovirology. 2007;4:57.
-
(2007)
Retrovirology
, vol.4
, pp. 57
-
-
Amarnath, S.1
Dong, L.2
Li, J.3
Wu, Y.4
Chen, W.5
-
33
-
-
35448930435
-
Induction of foxp3 expression in naive human cd41foxp3 t cells by t-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype
-
Tran DQ, Ramsey H, Shevach EM. Induction of FOXP3 expression in naive human CD41FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood. 2007;110(8):2983-2990.
-
(2007)
Blood
, vol.110
, Issue.8
, pp. 2983-2990
-
-
Tran, D.Q.1
Ramsey, H.2
Shevach, E.M.3
-
34
-
-
76749133610
-
Role of conserved non-coding dna elements in the foxp3 gene in regulatory t-cell fate
-
Zheng Y, Josefowicz S, Chaudhry A, Peng XP, Forbush K, Rudensky AY. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature. 2010;463(7282): 808-812.
-
(2010)
Nature
, vol.463
, Issue.7282
, pp. 808-812
-
-
Zheng, Y.1
Josefowicz, S.2
Chaudhry, A.3
Peng, X.P.4
Forbush, K.5
Rudensky, A.Y.6
-
35
-
-
55549139051
-
The expanding field of poly(adp-ribosyl)ation reactions. ‘protein modifications: Beyond the usual suspects’ review series
-
Hakmé A, Wong HK, Dantzer F, Schreiber V. The expanding field of poly(ADP-ribosyl)ation reactions. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series. EMBO Rep. 2008;9(11):1094-1100.
-
(2008)
EMBO Rep.
, vol.9
, Issue.11
, pp. 1094-1100
-
-
Hakmé, A.1
Wong, H.K.2
Dantzer, F.3
Schreiber, V.4
-
36
-
-
33745588297
-
Parp regulates tgf-beta receptor type ii expression in estrogen receptor-positive breast cancer cell lines
-
Sterling JA, Wu L, Banerji SS. PARP regulates TGF-beta receptor type II expression in estrogen receptor-positive breast cancer cell lines. Anticancer Res. 2006;26(3A):1893-1901.
-
(2006)
Anticancer Res.
, vol.26
, Issue.3
, pp. 1893-1901
-
-
Sterling, J.A.1
Wu, L.2
Banerji, S.S.3
-
37
-
-
80052020183
-
Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells
-
Pallotta MT, Orabona C, Volpi C, et al. Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells. Nat Immunol. 2011;12(9):870-878.
-
(2011)
Nat Immunol
, vol.12
, Issue.9
, pp. 870-878
-
-
Pallotta, M.T.1
Orabona, C.2
Volpi, C.3
-
38
-
-
77958584113
-
Generation of pathogenic t(h)17 cells in the absence of tgf-b signalling
-
Ghoreschi K, Laurence A, Yang X-P, et al. Generation of pathogenic T(H)17 cells in the absence of TGF-b signalling. Nature. 2010; 467(7318):967-971.
-
(2010)
Nature
, vol.467
, Issue.7318
, pp. 967-971
-
-
Ghoreschi, K.1
Laurence, A.2
Yang, X.-P.3
-
39
-
-
77954274504
-
The parp side of the nucleus: Molecular actions, physiological outcomes, and clinical targets
-
Krishnakumar R, Kraus WL. The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets. Mol Cell. 2010; 39(1):8-24.
-
(2010)
Mol Cell
, vol.39
, Issue.1
, pp. 8-24
-
-
Krishnakumar, R.1
Kraus, W.L.2
-
40
-
-
39149088997
-
Regulation of nfat by poly(adp-ribose) polymerase activity in t cells
-
Valdor R, Schreiber V, Saenz L, et al. Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells. Mol Immunol. 2008;45(7):1863-1871.
-
(2008)
Mol Immunol
, vol.45
, Issue.7
, pp. 1863-1871
-
-
Valdor, R.1
Schreiber, V.2
Saenz, L.3
-
41
-
-
33750314513
-
Poly(adp-ribose) polymerase-1 inhibition prevents eosinophil recruitment by modulating th2 cytokines in a murine model of allergic airway inflammation: A potential specific effect on il-5
-
published correction appears in J Immunol. 2007; 179(8):5604
-
Oumouna M, Datta R, Oumouna-Benachour K, et al. Poly(ADP-ribose) polymerase-1 inhibition prevents eosinophil recruitment by modulating Th2 cytokines in a murine model of allergic airway inflammation: a potential specific effect on IL-5 [published correction appears in J Immunol. 2007; 179(8):5604]. J Immunol. 2006;177(9): 6489-6496.
-
(2006)
J Immunol
, vol.177
, Issue.9
, pp. 6489-6496
-
-
Oumouna, M.1
Datta, R.2
Oumouna-Benachour, K.3
|