Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase

Gut

Volumn 53, Issue 9, 2004, Pages 1250-1255

  Nam, K T ^b   Oh, S Y ^a   Ahn, B ^b   Kim, Y B ^c   Jang, D D ^b   Yang, K H ^b   Hahm, K B ^c   Kim, D Y ^a  

^a Seoul National University   (South Korea)

^b Korea Food and Drug Administration   (South Korea)

^c Ajou University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; INDUCIBLE NITRIC OXIDE SYNTHASE; METHYLNITROSOUREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CARCINOMA CELL; COMPARATIVE STUDY; CONTROLLED STUDY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HISTOPATHOLOGY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LAMINA PROPRIA; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; STOMACH ADENOCARCINOMA; STOMACH CANCER; STOMACH CARCINOGENESIS; STOMACH TUMOR; TISSUE DISTRIBUTION; WILD TYPE;

ADENOCARCINOMA; ADENOMA; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; STOMACH; STOMACH NEOPLASMS; TYROSINE;

EID: 4344691283     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2003.030684     Document Type: Article

References (30)

1. Parkin DM, Laara E, Muir CS. Estimates of the worldwide frequency of sixteen major cancers in 1980. Int J Cancer 1998;41:184-97.
2. Ahn YO, Park BJ, Yoo KY, et al. Incidence estimation of female breast cancer among Koreans. J Korean Med Sci 1994;9:328-34.
3. Blaser MJ, Chyou PH, Nomura A. Age at establishment of Helicobacter pylori infection and gastric carcinoma, gastric ulcer, and duodenal ulcer risk. Cancer Res 1995;55:562-5.
4. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Helicobacter pylori. In: Schistosomes, liver flukes and Helicobacter pylori: Views and expert opinions of IARC Working Group on the Evaluation of Carcinogenic Risk to Humans. Lyon: IARC, 1994:177-240.
5. Ohshima H, Bartsch H. Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat Res 1994;305:253-64.
6. Nathan C, Xie QW. Nitric oxide synthases: roles, tolls, and controls. Cell 1994;78:915-18.
7. Jenkins DC, Charles IG, Thomsen LL, et al. Roles of nitric oxide in tumor growth. Proc Natl Acad Sci U S A 1995;92:4392-6.
8. Doi K, Akaike T, Horie H, et al. Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth. Cancer 1996;77:1598-604.
9. Feng CW, Wang LD, Jiao LH, et al. Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features. BMC Cancer 2002;2:8.
10. Rajnakava A, Moochhala S, Goh PM, et al. Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer. Cancer Lett 2001;172:177-85.
11. Antos D, Enders G, Rieder G, et al. Inducible nitric oxide synthase expression before and after eradication of Helicobacter pylori in different forms of gastritis. FEMS Immunol Med Microbiol 2001;30:127-31.
12. Goto T, Haruma K, Kitadai Y, et al. Enhanced expression of inducible nitric oxide synthase and nitrotyrosine in gastric mucosa of gastric cancer patients. Clin Cancer Res 1999;5:1411-15.
13. Min/+ mice by inhibiting nitric oxide production. Cancer Res, 2001;61, 8357-60.
14. Okamoto T, Masuda Y, Kawasaki T, et al. Aminoguanidine prevents concanavalin A-induced hepatitis in mice. Eur J Pharmacol 2000;396:125-30.
15. Yasuhiro T, Korolkiewicz RP, Kato S, et al. Role of nitric oxide in pathogenesis of serotonine-induced gastric lesions in rats. Pharmacol Res 1997;36:333-8.
16. Ribbons KA, Currie MG, Connor JR, et al. The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey. J Pharmacol Exp Ther 1997;280:1008-15.
17. Yoshida Y, Iwai A, Itoh K, et al. Role of inducible nitric oxide synthase in dextran sulphate sodium-induced colitis. Aliment Pharmacol Ther 2000;14:26-32.
18. MacMicking JD, Nathan C, Hom G, et al. Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell 1995;81:641-50.
19. Han SU, Kim YB, Joo HJ, et al. Helicobacter pylori infection promotes gastric carcinogenesis in a mice model. J Gastroenterol Hepatol 2002;17:253-61.
20. Leininger JR, Jokinen MP. Tumours of the oral cavity, pharynx, oesophagus and stomach. In: Turusov VS, Mohr U, eds. Pathology of tumours in laboratory animals. Lyon: IARC, 1994:167-93.
21. O'Byrne KJ, Dalgleish AG. Chronic immune activation and inflammation as the cause of malignancy. Br J Cancer 2001;85:473-83.
22. Mannick EE, Bravo LE, Zarama G, et al. Inducibie nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res 1996;56:3238-43.
23. Beckman JS, Koppenol WH. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 1996;271:C1424-37.
24. Ischiropoulos H, al-Mehdi AB. Peroxynitrite-mediated oxidative protein modifications. FEBS Lett 1995;364:279-82.
25. Haddad IY, Pataki G, Hu P, et al. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury. J Clin Invest 1994;94:2407-13.
26. Ahn B, Han BS, Kim DJ, et al. Immunohistochemical localization of inducible nitric oxide synthase and 3-nitrotyrosine in rot liver tumors induced by N-nitrosodiethylamine. Carcinogenesis 1999;20:1337-44.
27. Fu S, Ramanujam KS, Wong A, et al. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology 1999;116:1319-29.
28. Singer II, Kawka DW, Scott S, et al. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 1990;111:871-85.
29. Zingarelli B, Szabo C, Salzman AL. Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase. Gut 1999;45:199-209.
30. Krieglstein CF, Cerwinka WH, Laroux FS, et al. Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide. J Exp Med 2001;194:1207-18.