Ion mobility-mass spectrometry of intact protein-ligand complexes for pharmaceutical drug discovery and development

Current Opinion in Chemical Biology

Volumn 17, Issue 5, 2013, Pages 809-817

  Niu, Shuai ^a   Rabuck, Jessica N ^a   Ruotolo, Brandon T ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; LIGAND; MOLECULAR SCAFFOLD; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN;

CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME CONFORMATION; ION MOBILITY MASS SPECTROMETRY; LIGAND BINDING; MASS SPECTROMETRY; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STOICHIOMETRY;

DRUG DISCOVERY; HUMANS; IONS; LIGANDS; MASS SPECTROMETRY; PROTEIN MULTIMERIZATION; PROTEINS;

EID: 84887151962     PISSN: 13675931     EISSN: 18790402     Source Type: Journal    
DOI: 10.1016/j.cbpa.2013.06.019     Document Type: Review

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