PLIMSTEX: A novel mass spectrometric method for the quantification of protein-ligand interactions in solution

International Journal of Mass Spectrometry

Volumn 240, Issue 3 SPEC. ISS., 2005, Pages 213-220

  Zhu, Mei M ^a   Chitta, Raghu ^b   Gross, Michael L ^b  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Association constant; Conformational change; ESI MS; H D exchange; Protein ligand interaction

Indexed keywords

AMIDE; LIGAND; METAL ION; ORGANIC COMPOUND; PEPTIDE; PROTEIN;

ACCURACY; ANALYTIC METHOD; BINDING AFFINITY; BINDING ASSAY; CHEMICAL LABELING; CONCENTRATION (PARAMETERS); CONFERENCE PAPER; CONFORMATION; DENATURATION; ELECTROSPRAY MASS SPECTROMETRY; GAS; LIGAND BINDING; MASS; MASS SPECTROMETRY; MEASUREMENT; MOLECULE; PHYSICAL CHEMISTRY; PROTEIN BINDING; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REACTION ANALYSIS; REPRODUCIBILITY; SEPARATION TECHNIQUE; SPECTROSCOPY; STOICHIOMETRY; TITRIMETRY; VALIDATION PROCESS;

EID: 11844258744     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2004.09.012     Document Type: Conference Paper

References (68)

1. H.-J. Böhm, and G. Schneider Protein-ligand Interactions from Molecular Recognition to Drug Design 2003 Wiley-VCH Verlag GmbH, Weinheim Germany
2. G. Klebe, M. Bohm, F. Dullweber, U. Gradler, H. Gohlke, and M. Hendlich Proceedings of the European Symposium on Quantitative Structure-Activity Relationships: Molecular Modeling and Prediction of Bioactivity Copenhagen, Denmark 1998 103
3. R.C. Jackson Curr. Opin. Biotech. 6 1995 646
4. H. Gohlke, and G. Klebe Angew. Chem. Int. Ed. 41 2002 2644
5. B.M. Baker, and K.P. Murphy Methods Enzymol. 295 1998 294
6. R.B. Raffa H.-J. Böhm G. Schneider Protein-ligand Interactions vol. 19 2003 Wiley-VCH Verlag GmbH, Weinheim Germany 51
7. D.J. Wintor, and W.H. Sawyer Quantitative Characterrization of Ligand Binding 1995 John Wiley & Sons USA
8. B. Sebille Fundam. Clin. Pharmacol. 4 Suppl. 2 1990 151
9. C.R. Cantor, P.R. Schimmel, in: W.H. Freeman (Ed.), San Francisco, 1980, p. 344.
10. M.M. Zhu, D.L. Rempel, Z. Du, and M.L. Gross J. Am. Chem. Soc. 125 2003 5252
11. M.M. Zhu, D.L. Rempel, and M.L. Gross J. Am. Soc. Mass Spectrom. 15 2004 388
12. M.M. Zhu, D.L. Rempel, J. Zhao, D.E. Giblin, and M.L. Gross Biochemistry 42 2003 15388
13. M.M. Zhu, Determination of Protein-ligand Interactions Using H/D Exchange and Mass Spectrometry, Ph.D. Dissertation, Washington University, St. Louis, Missouri, USA, 2004, p. 338.
14. R. Chitta, D.L. Rempel, M.A. Grayson, and M.L. Gross Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics Nashville, Tennessee, USA 2004
15. A. Scaloni, N. Miraglia, S. Orrù, P. Amodeo, A. Motta, G. Marino, and P. Pucci J. Mol. Biol. 277 1998 945
16. J.R. Yates III J. Mass Spectrom. 33 1998 1
17. P.L. Ferguson, and R.D. Smith Annu. Rev. Biophys. Biomol. Struct. 32 2003 399
18. J.A. Loo Mass Spectrom. Rev. 16 1997 1
19. J.A. Loo Int. J. Mass Spectrom. 200 2000 175
20. F. Hillenkamp NATO ASI Ser., Ser. C. 510 1998 181
21. K.A. Sannes-Lowery, R.H. Griffey, and S.A. Hofstadler Anal. Biochem. 280 2000 264
22. F. Rosu, V. Gabelica, C. Houssier, and E. De Pauw Adv. Mass Spectrom. 15 2001 795
23. S. Zhang, C.K. Van Pelt, and D.B. Wilson Anal. Chem. 75 2003 3010
24. S.W.A. Bligh, T. Haley, and P.N. Lowe J. Mol. Recognit. 16 2003 139
25. J.A. Loo, P. Hu, P. McConnell, and W.T. Mueller J. Am. Soc. Mass Spectrom. 8 1997 234
26. H.-K. Lim, Y.L. Hsieh, B. Ganem, and J. Henion J. Mass Spectrom. 30 1995 708
27. M.J. Greig, H. Gaus, L.L. Cummins, H. Sasmor, and R.H. Griffey J. Am. Chem. Soc. 117 1995 10765
28. L.E. Sojo, G. Lum, and P. Chee Analyst (Cambridge, United Kingdom) 128 2003 51
29. H.R. Liang, R.L. Foltz, M. Meng, and P. Bennett Rapid Commun. Mass Spectrom. 17 2003 2815
30. C.V. Robinson, E.W. Chung, B.B. Kragelund, R.T. Aplin, F.M. Poulsen, and C.M. Dobson J. Am. Chem. Soc. 118 1996 8646
31. Q. Wu, J. Gao, D. Joseph-McCarthy, G.B. Sigal, J.E. Bruce, G.M. Whitesides, and R.D. Smith J. Am. Chem. Soc. 119 1997 1157
32. A. Tjernberg, S. Carnö, F. Oliv, K. Benkestock, P.-O. Edlund, W.J. Griffiths, and D. Hallén Anal. Chem. 76 2004 4325
33. L. Tang, and P. Kebarle Anal. Chem. 65 1993 3654
34. D.R. Zook, and A.P. Bruins Int. J. Mass Spectrom. Ion Proc. 162 1997 129
35. M.G. Ikonomou, A.T. Blades, and P. Kebarle Anal. Chem. 62 1990 957
36. N.B. Cech, and C.G. Enke Mass Spectrom. Rev. 20 2002 362
37. A.P. Bruins Electrospray Ion. Mass Spectrom. 1997 107
38. C.G. Zampronio, A.E. Giannakopulos, M. Zeller, E. Bitziou, J.V. Macpherson, and P.J. Derrick Anal. Chem. 76 2004 5172
39. M.A. Shea, B.R. Sorensen, S. Pedigo, and A.S. Verhoeven Methods Enzymol. 323 2000 254
40. K.D. Powell, S. Ghaemmaghami, M.Z. Wang, L. Ma, T.G. Oas, and M.C. Fitzgerald J. Am. Chem. Soc. 124 2002 10256
41. L. Ma, and M.C. Fitzgerald Chem. Biol. 10 2003 1205
42. E. Kurian, W.R. Kirk, and F.G. Prendergast Biochemistry 35 1996 3865
43. K.D. Powell, and M.C. Fitzgerald Anal. Chem. 73 2001 3300
44. K.D. Powell, T.E. Wales, and M.C. Fitzgerald Protein Sci. 11 2002 841
45. K.D. Powell, M.Z. Wang, P. Silinski, L. Ma, T.E. Wales, S.Y. Dai, A.H. Warner, X. Yang, and M.C. Fitzgerald Anal. Chim. Acta 496 2003 225
46. S.H. McLaughlin, and S.E. Jackson Protein Sci. 11 2002 1926
47. C.P.M. van Mierlo, and E. Steensma J. Biotech. 79 2000 281
48. N.J. Greenfield Methods Mol. Biol. (Clifton N.J.) 261 2004 55
49. K.D. Powell, and M.C. Fitzgerald Biochemistry 42 2003 4962
50. K.S. Lam, and M. Renil Curr. Opin. Chem. Biol. 6 2002 353
51. G. Metz, H. Ottleben, and D. Vetter H.-J. Böhm G. Schneider Protein-Ligand Interactions vol. 19 2003 Wiley-VCH Verlag GmbH, Weinheim Germany 213
52. Q. Xu, and K.S. Lam J. Biomed. Biotech. 5 2003 257
53. K.D. Kumble Anal. Bioanal. Chem. 377 2003 812
54. Y. Hamuro, S.J. Coales, M.R. Southern, J.F. Nemeth-Cawley, and D.D. Stranz J. Biomol. Tech. 14 2003 171
55. K.D. Powell, and M.C. Fitzgerald J. Combinatorial Chem. 6 2004 262
56. Z. Zhang, and D.L. Smith Protein Sci. 2 1993 522
57. D.L. Smith, and K. Dharmasiri NATO ASI Ser. Ser. C. 510 1998 45
58. J.R. Engen, W.H. Gmeiner, T.E. Smithgall, and D.L. Smith Biochemistry 38 1999 8926
59. F. Wang, W. Li, M.R. Emmett, A.G. Marshall, D. Corson, and B.D. Sykes J. Am. Soc. Mass Spectrom. 10 1999 703
60. V.L. Woods Jr., and Y. Hamuro Biochemistry Suppl. 37 2001 89
61. Y. Hamuro, L. Wong, J. Shaffer, J.S. Kim, D.D. Stranz, P.A. Jennings, V.L. Woods Jr., and J.A. Adams J. Mol. Biol. 323 2002 871
62. M.M. Zhu, D.L. Rempel, I. Vidavsky, and M.L. Gross Proceedings of the 52nd ASMS Conference on Mass Spectrometry and Allied Topics Nashville, Tennessee, USA 2004
63. L. Wang, H. Pan, and D.L. Smith Mol. Cell. Proteomics 1 2002 132
64. J. Zhang, and C.R. Matthews Biochemistry 37 1998 14881
65. S. Linse, A. Helmersson, and S. Forsén J. Biol. Chem. 266 1991 8050
66. M. Comte, Y. Maulet, and J.A. Cox Biochem. J. 209 1983 269
67. Y. Yao, and T.C. Squier Biochemistry 35 1996 6815
68. Y. Pocker, and S.B. Biswas Biochemistry 20 1981 4354