Modeling data from titration, amide H/D exchange, and mass spectrometry to obtain protein-ligand binding constants

Journal of the American Society for Mass Spectrometry

Volumn 15, Issue 3, 2004, Pages 388-397

  Zhu, Mei M ^a   Rempel, Don L ^a   Gross, Michael L ^a  

^a WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; DEUTERIUM; FATTY ACIDS; MASS SPECTROMETRY; NITROGEN COMPOUNDS; ORDINARY DIFFERENTIAL EQUATIONS; STOICHIOMETRY; TITRATION;

INTESTINAL FATTY ACID BINDING PROTEINS (IFABP); SEQUENTIAL BINDING;

PROTEINS;

AMIDE; CALCIUM; CALMODULIN; CARBOXYLIC ACID; DEUTERIUM; FATTY ACID BINDING PROTEIN; LIGAND; PROTEIN;

MASS SPECTROMETRY;

ACCURACY; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCULATION; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); ELECTROSPRAY MASS SPECTROMETRY; ERROR; LIGAND BINDING; MASS SPECTROMETRY; MEASUREMENT; MODEL; NONLINEAR SYSTEM; PARAMETER; PROTEIN BINDING; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; SAMPLING; STATISTICS; STOICHIOMETRY; TITRIMETRY;

AMIDES; CALCIUM; CALMODULIN; DEUTERIUM EXCHANGE MEASUREMENT; LIGANDS; MODELS, MOLECULAR; PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THERMODYNAMICS; TITRIMETRY;

EID: 1442333529     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jasms.2003.11.007     Document Type: Article

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