-
1
-
-
1842611887
-
The endocannabinoid system: A general view and latest additions
-
De Petrocellis, L., Cascio, M. G., and Di Marzo, V. (2004) The endocannabinoid system: A general view and latest additions Br. J. Pharmacol. 141, 765-774
-
(2004)
Br. J. Pharmacol.
, vol.141
, pp. 765-774
-
-
De Petrocellis, L.1
Cascio, M.G.2
Di Marzo, V.3
-
2
-
-
26844504226
-
Identification and functional characterization of brainstem cannabinoid CB2 receptors
-
Van Sickle, M. D., Duncan, M., Kingsley, P. J., Mouihate, A., Urbani, P., Mackie, K., Stella, N., Makriyannis, A., Piomelli, D., Davison, J. S., Marnett, L. J., Di Marzo, V., Pittman, Q. J., Patel, K. D., and Sharkey, K. A. (2005) Identification and functional characterization of brainstem cannabinoid CB2 receptors Science 310, 329-332
-
(2005)
Science
, vol.310
, pp. 329-332
-
-
Van Sickle, M.D.1
Duncan, M.2
Kingsley, P.J.3
Mouihate, A.4
Urbani, P.5
Mackie, K.6
Stella, N.7
Makriyannis, A.8
Piomelli, D.9
Davison, J.S.10
Marnett, L.J.11
Di Marzo, V.12
Pittman, Q.J.13
Patel, K.D.14
Sharkey, K.A.15
-
3
-
-
0346350327
-
The cannabinoid system and immune modulation
-
Klein, T. W., Newton, C., Larsen, K., Lu, L., Perkins, I., Nong, L., and Friedman, H. (2003) The cannabinoid system and immune modulation J. Leukocyte Biol. 74, 486-496
-
(2003)
J. Leukocyte Biol.
, vol.74
, pp. 486-496
-
-
Klein, T.W.1
Newton, C.2
Larsen, K.3
Lu, L.4
Perkins, I.5
Nong, L.6
Friedman, H.7
-
4
-
-
67449119913
-
The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation
-
Di Marzo, V. (2009) The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation Pharmacol. Res. 60, 77-84
-
(2009)
Pharmacol. Res.
, vol.60
, pp. 77-84
-
-
Di Marzo, V.1
-
5
-
-
42349116948
-
The role of the endocannabinoid system in atherosclerosis
-
Mach, F. and Steffens, S. (2008) The role of the endocannabinoid system in atherosclerosis J. Neuroendocrinol. 20 (Suppl. 1) 53-57
-
(2008)
J. Neuroendocrinol.
, vol.20
, Issue.SUPPL. 1
, pp. 53-57
-
-
Mach, F.1
Steffens, S.2
-
6
-
-
37149013708
-
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol
-
Blankman, J. L., Simon, G. M., and Cravatt, B. F. (2007) A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2- arachidonoylglycerol Chem. Biol. 14, 1347-1356
-
(2007)
Chem. Biol.
, vol.14
, pp. 1347-1356
-
-
Blankman, J.L.1
Simon, G.M.2
Cravatt, B.F.3
-
7
-
-
33947330328
-
Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells
-
Muccioli, G. G., Xu, C., Odah, E., Cudaback, E., Cisneros, J. A., Lambert, D. M., Lopez Rodriguez, M. L., Bajjalieh, S., and Stella, N. (2007) Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells J. Neurosci. 27, 2883-2889
-
(2007)
J. Neurosci.
, vol.27
, pp. 2883-2889
-
-
Muccioli, G.G.1
Xu, C.2
Odah, E.3
Cudaback, E.4
Cisneros, J.A.5
Lambert, D.M.6
Lopez Rodriguez, M.L.7
Bajjalieh, S.8
Stella, N.9
-
8
-
-
77955053537
-
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
-
Marrs, W. R., Blankman, J. L., Horne, E. A., Thomazeau, A., Lin, Y. H., Coy, J., Bodor, A. L., Muccioli, G. G., Hu, S. S., Woodruff, G., Fung, S., Lafourcade, M., Alexander, J. P., Long, J. Z., Li, W., Xu, C., Moller, T., Mackie, K., Manzoni, O. J., Cravatt, B. F., and Stella, N. (2010) The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors Nat. Neurosci. 13, 951-957
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 951-957
-
-
Marrs, W.R.1
Blankman, J.L.2
Horne, E.A.3
Thomazeau, A.4
Lin, Y.H.5
Coy, J.6
Bodor, A.L.7
Muccioli, G.G.8
Hu, S.S.9
Woodruff, G.10
Fung, S.11
Lafourcade, M.12
Alexander, J.P.13
Long, J.Z.14
Li, W.15
Xu, C.16
Moller, T.17
Mackie, K.18
Manzoni, O.J.19
Cravatt, B.F.20
Stella, N.21
more..
-
9
-
-
84867339289
-
Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)
-
Navia-Paldanius, D., Savinainen, J. R., and Laitinen, J. T. (2012) Biochemical and pharmacological characterization of human α/β- hydrolase domain containing 6 (ABHD6) and 12 (ABHD12) J. Lipid Res. 53, 2413-2424
-
(2012)
J. Lipid Res.
, vol.53
, pp. 2413-2424
-
-
Navia-Paldanius, D.1
Savinainen, J.R.2
Laitinen, J.T.3
-
10
-
-
78650452903
-
Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: Role of carboxylesterases 1 and 2
-
Xie, S., Borazjani, A., Hatfield, M. J., Edwards, C. C., Potter, P. M., and Ross, M. K. (2010) Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: Role of carboxylesterases 1 and 2 Chem. Res. Toxicol. 23, 1890-1904
-
(2010)
Chem. Res. Toxicol.
, vol.23
, pp. 1890-1904
-
-
Xie, S.1
Borazjani, A.2
Hatfield, M.J.3
Edwards, C.C.4
Potter, P.M.5
Ross, M.K.6
-
11
-
-
84861408917
-
Examination of the carboxylesterase phenotype in human liver
-
Ross, M. K., Borazjani, A., Wang, R., Crow, J. A., and Xie, S. (2012) Examination of the carboxylesterase phenotype in human liver Arch. Biochem. Biophys. 522, 44-56
-
(2012)
Arch. Biochem. Biophys.
, vol.522
, pp. 44-56
-
-
Ross, M.K.1
Borazjani, A.2
Wang, R.3
Crow, J.A.4
Xie, S.5
-
12
-
-
0034707495
-
Cholesteryl ester hydrolase in human monocyte/macrophage: Cloning, sequencing, and expression of full-length cDNA
-
Ghosh, S. (2000) Cholesteryl ester hydrolase in human monocyte/macrophage: Cloning, sequencing, and expression of full-length cDNA Physiol. Genomics 2, 1-8
-
(2000)
Physiol. Genomics
, vol.2
, pp. 1-8
-
-
Ghosh, S.1
-
13
-
-
79958851217
-
Role of endoplasmic reticulum neutral lipid hydrolases
-
Quiroga, A. D. and Lehner, R. (2011) Role of endoplasmic reticulum neutral lipid hydrolases Trends Endocrinol. Metab. 22, 218-225
-
(2011)
Trends Endocrinol. Metab.
, vol.22
, pp. 218-225
-
-
Quiroga, A.D.1
Lehner, R.2
-
14
-
-
52349103153
-
Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages
-
Crow, J. A., Middleton, B. L., Borazjani, A., Hatfield, M. J., Potter, P. M., and Ross, M. K. (2008) Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages Biochim. Biophys. Acta 1781, 643-654
-
(2008)
Biochim. Biophys. Acta
, vol.1781
, pp. 643-654
-
-
Crow, J.A.1
Middleton, B.L.2
Borazjani, A.3
Hatfield, M.J.4
Potter, P.M.5
Ross, M.K.6
-
15
-
-
22844449458
-
Glycerylprostaglandin synthesis by resident peritoneal macrophages in response to a zymosan stimulus
-
Rouzer, C. A. and Marnett, L. J. (2005) Glycerylprostaglandin synthesis by resident peritoneal macrophages in response to a zymosan stimulus J. Biol. Chem. 280, 26690-26700
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 26690-26700
-
-
Rouzer, C.A.1
Marnett, L.J.2
-
16
-
-
80054080661
-
Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: Cross-talk between the eicosanoid and endocannabinoid signaling pathways
-
Rouzer, C. A. and Marnett, L. J. (2011) Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: Cross-talk between the eicosanoid and endocannabinoid signaling pathways Chem. Rev. 111, 5899-5921
-
(2011)
Chem. Rev.
, vol.111
, pp. 5899-5921
-
-
Rouzer, C.A.1
Marnett, L.J.2
-
17
-
-
34547789923
-
A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases
-
Li, W., Blankman, J. L., and Cravatt, B. F. (2007) A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases J. Am. Chem. Soc. 129, 9594-9595
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 9594-9595
-
-
Li, W.1
Blankman, J.L.2
Cravatt, B.F.3
-
18
-
-
0033593013
-
Activity-based protein profiling: The serine hydrolases
-
Liu, Y., Patricelli, M. P., and Cravatt, B. F. (1999) Activity-based protein profiling: The serine hydrolases Proc. Natl. Acad. Sci. U.S.A. 96, 14694-14699
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 14694-14699
-
-
Liu, Y.1
Patricelli, M.P.2
Cravatt, B.F.3
-
19
-
-
80052861411
-
Catabolism of 4-hydroxy-2-trans-nonenal by THP1 monocytes/macrophages and inactivation of carboxylesterases by this lipid electrophile
-
Borazjani, A., Edelmann, M. J., Hardin, K. L., Herring, K. L., Allen Crow, J., and Ross, M. K. (2011) Catabolism of 4-hydroxy-2-trans-nonenal by THP1 monocytes/macrophages and inactivation of carboxylesterases by this lipid electrophile Chem.-Biol. Interact. 194, 1-12
-
(2011)
Chem.-Biol. Interact.
, vol.194
, pp. 1-12
-
-
Borazjani, A.1
Edelmann, M.J.2
Hardin, K.L.3
Herring, K.L.4
Allen Crow, J.5
Ross, M.K.6
-
20
-
-
84856402803
-
How chemoproteomics can enable drug discovery and development
-
Moellering, R. E. and Cravatt, B. F. (2012) How chemoproteomics can enable drug discovery and development Chem. Biol. 19, 11-22
-
(2012)
Chem. Biol.
, vol.19
, pp. 11-22
-
-
Moellering, R.E.1
Cravatt, B.F.2
-
21
-
-
33746075254
-
Thematic review series: Lipid posttranslational modifications. Lysosomal metabolism of lipid-modified proteins
-
Lu, J. Y. and Hofmann, S. L. (2006) Thematic review series: Lipid posttranslational modifications. Lysosomal metabolism of lipid-modified proteins J. Lipid Res. 47, 1352-1357
-
(2006)
J. Lipid Res.
, vol.47
, pp. 1352-1357
-
-
Lu, J.Y.1
Hofmann, S.L.2
-
22
-
-
0034468634
-
Comparison of Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Spodoptera frugiperda, and COS7 cells for recombinant gene expression. Application to a rabbit liver carboxylesterase
-
Morton, C. L. and Potter, P. M. (2000) Comparison of Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Spodoptera frugiperda, and COS7 cells for recombinant gene expression. Application to a rabbit liver carboxylesterase Mol. Biotechnol. 16, 193-202
-
(2000)
Mol. Biotechnol.
, vol.16
, pp. 193-202
-
-
Morton, C.L.1
Potter, P.M.2
-
23
-
-
84874027224
-
Activity-Based Protein Profiling (ABPP) and Click Chemistry (CC)-ABPP by MudPIT Mass Spectrometry
-
Speers, A. E. and Cravatt, B. F. (2009) Activity-Based Protein Profiling (ABPP) and Click Chemistry (CC)-ABPP by MudPIT Mass Spectrometry Curr. Protoc. Chem. Biol. 1, 29-41
-
(2009)
Curr. Protoc. Chem. Biol.
, vol.1
, pp. 29-41
-
-
Speers, A.E.1
Cravatt, B.F.2
-
24
-
-
0036828724
-
Probability-based validation of protein identifications using a modified SEQUEST algorithm
-
MacCoss, M. J., Wu, C. C., and Yates, J. R., III (2002) Probability-based validation of protein identifications using a modified SEQUEST algorithm Anal. Chem. 74, 5593-5599
-
(2002)
Anal. Chem.
, vol.74
, pp. 5593-5599
-
-
Maccoss, M.J.1
Wu, C.C.2
Yates III, J.R.3
-
25
-
-
77649337157
-
Human recombinant palmitoyl-protein thioesterase-1 (PPT1) for preclinical evaluation of enzyme replacement therapy for infantile neuronal ceroid lipofuscinosis
-
Lu, J. Y., Hu, J., and Hofmann, S. L. (2010) Human recombinant palmitoyl-protein thioesterase-1 (PPT1) for preclinical evaluation of enzyme replacement therapy for infantile neuronal ceroid lipofuscinosis Mol. Genet. Metab. 99, 374-378
-
(2010)
Mol. Genet. Metab.
, vol.99
, pp. 374-378
-
-
Lu, J.Y.1
Hu, J.2
Hofmann, S.L.3
-
26
-
-
84874735161
-
-
Enzymatic activity of human carboxylesterases. Chapter 4, Unit 4, 24, Wiley, New York.
-
Ross, M. K. and Borazjani, A. (2007) Enzymatic activity of human carboxylesterases. Current protocols in toxicology, Chapter 4, Unit 4, 24, Wiley, New York.
-
(2007)
Current Protocols in Toxicology
-
-
Ross, M.K.1
Borazjani, A.2
-
27
-
-
0035923662
-
Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice
-
Gupta, P., Soyombo, A. A., Atashband, A., Wisniewski, K. E., Shelton, J. M., Richardson, J. A., Hammer, R. E., and Hofmann, S. L. (2001) Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice Proc. Natl. Acad. Sci. U.S.A. 98, 13566-13571
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 13566-13571
-
-
Gupta, P.1
Soyombo, A.A.2
Atashband, A.3
Wisniewski, K.E.4
Shelton, J.M.5
Richardson, J.A.6
Hammer, R.E.7
Hofmann, S.L.8
-
28
-
-
78650495439
-
Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening
-
Bachovchin, D. A., Ji, T., Li, W., Simon, G. M., Blankman, J. L., Adibekian, A., Hoover, H., Niessen, S., and Cravatt, B. F. (2010) Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening Proc. Natl. Acad. Sci. U.S.A. 107, 20941-20946
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 20941-20946
-
-
Bachovchin, D.A.1
Ji, T.2
Li, W.3
Simon, G.M.4
Blankman, J.L.5
Adibekian, A.6
Hoover, H.7
Niessen, S.8
Cravatt, B.F.9
-
29
-
-
84870373692
-
DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses
-
Hsu, K. L., Tsuboi, K., Adibekian, A., Pugh, H., Masuda, K., and Cravatt, B. F. (2012) DAGLβ inhibition perturbs a lipid network involved in macrophage inflammatory responses Nat. Chem. Biol. 8, 999-1007
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 999-1007
-
-
Hsu, K.L.1
Tsuboi, K.2
Adibekian, A.3
Pugh, H.4
Masuda, K.5
Cravatt, B.F.6
-
30
-
-
0034712969
-
The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis
-
Bellizzi, J. J., III, Widom, J., Kemp, C., Lu, J. Y., Das, A. K., Hofmann, S. L., and Clardy, J. (2000) The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis Proc. Natl. Acad. Sci. U.S.A. 97, 4573-4578
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 4573-4578
-
-
Bellizzi III, J.J.1
Widom, J.2
Kemp, C.3
Lu, J.Y.4
Das, A.K.5
Hofmann, S.L.6
Clardy, J.7
-
31
-
-
20944443990
-
Identification and characterization of novel benzil (diphenylethane-1,2- dione) analogues as inhibitors of mammalian carboxylesterases
-
Wadkins, R. M., Hyatt, J. L., Wei, X., Yoon, K. J., Wierdl, M., Edwards, C. C., Morton, C. L., Obenauer, J. C., Damodaran, K., Beroza, P., Danks, M. K., and Potter, P. M. (2005) Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases J. Med. Chem. 48, 2906-2915
-
(2005)
J. Med. Chem.
, vol.48
, pp. 2906-2915
-
-
Wadkins, R.M.1
Hyatt, J.L.2
Wei, X.3
Yoon, K.J.4
Wierdl, M.5
Edwards, C.C.6
Morton, C.L.7
Obenauer, J.C.8
Damodaran, K.9
Beroza, P.10
Danks, M.K.11
Potter, P.M.12
-
32
-
-
81055156684
-
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
-
Nomura, D. K., Morrison, B. E., Blankman, J. L., Long, J. Z., Kinsey, S. G., Marcondes, M. C., Ward, A. M., Hahn, Y. K., Lichtman, A. H., Conti, B., and Cravatt, B. F. (2011) Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation Science 334, 809-813
-
(2011)
Science
, vol.334
, pp. 809-813
-
-
Nomura, D.K.1
Morrison, B.E.2
Blankman, J.L.3
Long, J.Z.4
Kinsey, S.G.5
Marcondes, M.C.6
Ward, A.M.7
Hahn, Y.K.8
Lichtman, A.H.9
Conti, B.10
Cravatt, B.F.11
-
33
-
-
84896404023
-
Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy
-
Alhouayek, M., Masquelier, J., and Muccioli, G. G. (2013) Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy Drug Discovery Today DOI: 10.1016/j.drudis.2013.07.009
-
(2013)
Drug Discovery Today
-
-
Alhouayek, M.1
Masquelier, J.2
Muccioli, G.G.3
-
34
-
-
0036882394
-
Serine protease mechanism and specificity
-
Hedstrom, L. (2002) Serine protease mechanism and specificity Chem. Rev. 102, 4501-4524
-
(2002)
Chem. Rev.
, vol.102
, pp. 4501-4524
-
-
Hedstrom, L.1
-
35
-
-
34548068590
-
Hydrolysis of prostaglandin glycerol esters by the endocannabinoid- hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase
-
Vila, A., Rosengarth, A., Piomelli, D., Cravatt, B., and Marnett, L. J. (2007) Hydrolysis of prostaglandin glycerol esters by the endocannabinoid- hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase Biochemistry 46, 9578-9585
-
(2007)
Biochemistry
, vol.46
, pp. 9578-9585
-
-
Vila, A.1
Rosengarth, A.2
Piomelli, D.3
Cravatt, B.4
Marnett, L.J.5
-
36
-
-
84855429902
-
Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon
-
Crow, J. A., Bittles, V., Herring, K. L., Borazjani, A., Potter, P. M., and Ross, M. K. (2012) Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon Toxicol. Appl. Pharmacol. 258, 145-150
-
(2012)
Toxicol. Appl. Pharmacol.
, vol.258
, pp. 145-150
-
-
Crow, J.A.1
Bittles, V.2
Herring, K.L.3
Borazjani, A.4
Potter, P.M.5
Ross, M.K.6
-
37
-
-
0034604567
-
Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride
-
Das, A. K., Bellizzi, J. J., III, Tandel, S., Biehl, E., Clardy, J., and Hofmann, S. L. (2000) Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride J. Biol. Chem. 275, 23847-23851
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23847-23851
-
-
Das, A.K.1
Bellizzi III, J.J.2
Tandel, S.3
Biehl, E.4
Clardy, J.5
Hofmann, S.L.6
-
38
-
-
84866615552
-
Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597
-
Crow, J. A., Bittles, V., Borazjani, A., Potter, P. M., and Ross, M. K. (2012) Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597 Biochem. Pharmacol. 84, 1215-1222
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 1215-1222
-
-
Crow, J.A.1
Bittles, V.2
Borazjani, A.3
Potter, P.M.4
Ross, M.K.5
-
39
-
-
33645658751
-
Inefficient cleavage of palmitoyl-protein thioesterase (PPT) substrates by aminothiols: Implications for treatment of infantile neuronal ceroid lipofuscinosis
-
Lu, J. Y. and Hofmann, S. L. (2006) Inefficient cleavage of palmitoyl-protein thioesterase (PPT) substrates by aminothiols: Implications for treatment of infantile neuronal ceroid lipofuscinosis J. Inherited Metab. Dis. 29, 119-126
-
(2006)
J. Inherited Metab. Dis.
, vol.29
, pp. 119-126
-
-
Lu, J.Y.1
Hofmann, S.L.2
-
40
-
-
0030009044
-
Lysosomal targeting of palmitoyl-protein thioesterase
-
Verkruyse, L. A. and Hofmann, S. L. (1996) Lysosomal targeting of palmitoyl-protein thioesterase J. Biol. Chem. 271, 15831-15836
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15831-15836
-
-
Verkruyse, L.A.1
Hofmann, S.L.2
-
41
-
-
0027518208
-
Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras
-
Camp, L. A. and Hofmann, S. L. (1993) Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras J. Biol. Chem. 268, 22566-22574
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 22566-22574
-
-
Camp, L.A.1
Hofmann, S.L.2
-
42
-
-
0030585740
-
CDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis
-
Schriner, J. E., Yi, W., and Hofmann, S. L. (1996) cDNA and genomic cloning of human palmitoyl-protein thioesterase (PPT), the enzyme defective in infantile neuronal ceroid lipofuscinosis Genomics 34, 317-322
-
(1996)
Genomics
, vol.34
, pp. 317-322
-
-
Schriner, J.E.1
Yi, W.2
Hofmann, S.L.3
-
43
-
-
0033408370
-
Developmental expression of palmitoyl protein thioesterase in normal mice
-
Isosomppi, J., Heinonen, O., Hiltunen, J. O., Greene, N. D., Vesa, J., Uusitalo, A., Mitchison, H. M., Saarma, M., Jalanko, A., and Peltonen, L. (1999) Developmental expression of palmitoyl protein thioesterase in normal mice Brain Research and Developmental Brain Research 118, 1-11
-
(1999)
Brain Research and Developmental Brain Research
, vol.118
, pp. 1-11
-
-
Isosomppi, J.1
Heinonen, O.2
Hiltunen, J.O.3
Greene, N.D.4
Vesa, J.5
Uusitalo, A.6
Mitchison, H.M.7
Saarma, M.8
Jalanko, A.9
Peltonen, L.10
-
44
-
-
34447345112
-
Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1): Distinct characteristics in neurons
-
Lyly, A., von Schantz, C., Salonen, T., Kopra, O., Saarela, J., Jauhiainen, M., Kyttala, A., and Jalanko, A. (2007) Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1): Distinct characteristics in neurons BMC Cell Biol. 8, 22
-
(2007)
BMC Cell Biol.
, vol.8
, pp. 22
-
-
Lyly, A.1
Von Schantz, C.2
Salonen, T.3
Kopra, O.4
Saarela, J.5
Jauhiainen, M.6
Kyttala, A.7
Jalanko, A.8
-
45
-
-
0032770135
-
The expression of palmitoyl-protein thioesterase is developmentally regulated in neural tissues but not in nonneural tissues
-
Suopanki, J., Tyynela, J., Baumann, M., and Haltia, M. (1999) The expression of palmitoyl-protein thioesterase is developmentally regulated in neural tissues but not in nonneural tissues Mol. Genet. Metab. 66, 290-293
-
(1999)
Mol. Genet. Metab.
, vol.66
, pp. 290-293
-
-
Suopanki, J.1
Tyynela, J.2
Baumann, M.3
Haltia, M.4
-
46
-
-
0342803576
-
Expression of palmitoyl protein thioesterase in neurons
-
Heinonen, O., Kyttala, A., Lehmus, E., Paunio, T., Peltonen, L., and Jalanko, A. (2000) Expression of palmitoyl protein thioesterase in neurons Mol. Genet. Metab. 69, 123-129
-
(2000)
Mol. Genet. Metab.
, vol.69
, pp. 123-129
-
-
Heinonen, O.1
Kyttala, A.2
Lehmus, E.3
Paunio, T.4
Peltonen, L.5
Jalanko, A.6
-
47
-
-
0035167162
-
Palmitoyl protein thioesterase (PPT) localizes into synaptosomes and synaptic vesicles in neurons: Implications for infantile neuronal ceroid lipofuscinosis (INCL)
-
Lehtovirta, M., Kyttala, A., Eskelinen, E. L., Hess, M., Heinonen, O., and Jalanko, A. (2001) Palmitoyl protein thioesterase (PPT) localizes into synaptosomes and synaptic vesicles in neurons: Implications for infantile neuronal ceroid lipofuscinosis (INCL) Hum. Mol. Genet. 10, 69-75
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 69-75
-
-
Lehtovirta, M.1
Kyttala, A.2
Eskelinen, E.L.3
Hess, M.4
Heinonen, O.5
Jalanko, A.6
-
48
-
-
0037434057
-
Palmitoyl protein thioesterase 1 is targeted to the axons in neurons
-
Ahtiainen, L., Van Diggelen, O. P., Jalanko, A., and Kopra, O. (2003) Palmitoyl protein thioesterase 1 is targeted to the axons in neurons J. Comp. Neurol. 455, 368-377
-
(2003)
J. Comp. Neurol.
, vol.455
, pp. 368-377
-
-
Ahtiainen, L.1
Van Diggelen, O.P.2
Jalanko, A.3
Kopra, O.4
-
49
-
-
0029153109
-
Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis
-
Vesa, J., Hellsten, E., Verkruyse, L. A., Camp, L. A., Rapola, J., Santavuori, P., Hofmann, S. L., and Peltonen, L. (1995) Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis Nature 376, 584-587
-
(1995)
Nature
, vol.376
, pp. 584-587
-
-
Vesa, J.1
Hellsten, E.2
Verkruyse, L.A.3
Camp, L.A.4
Rapola, J.5
Santavuori, P.6
Hofmann, S.L.7
Peltonen, L.8
-
50
-
-
1042265181
-
Current state of clinical and morphological features in human NCL
-
Goebel, H. H. and Wisniewski, K. E. (2004) Current state of clinical and morphological features in human NCL Brain Pathol. 14, 61-69
-
(2004)
Brain Pathol.
, vol.14
, pp. 61-69
-
-
Goebel, H.H.1
Wisniewski, K.E.2
-
51
-
-
0032776836
-
Tissue expression and subcellular localization of CLN3, the Batten disease protein
-
Margraf, L. R., Boriack, R. L., Routheut, A. A., Cuppen, I., Alhilali, L., Bennett, C. J., and Bennett, M. J. (1999) Tissue expression and subcellular localization of CLN3, the Batten disease protein Mol. Genet. Metab. 66, 283-289
-
(1999)
Mol. Genet. Metab.
, vol.66
, pp. 283-289
-
-
Margraf, L.R.1
Boriack, R.L.2
Routheut, A.A.3
Cuppen, I.4
Alhilali, L.5
Bennett, C.J.6
Bennett, M.J.7
-
52
-
-
79958097953
-
The moderately efficient enzyme: Evolutionary and physicochemical trends shaping enzyme parameters
-
Bar-Even, A., Noor, E., Savir, Y., Liebermeister, W., Davidi, D., Tawfik, D. S., and Milo, R. (2011) The moderately efficient enzyme: Evolutionary and physicochemical trends shaping enzyme parameters Biochemistry 50, 4402-4410
-
(2011)
Biochemistry
, vol.50
, pp. 4402-4410
-
-
Bar-Even, A.1
Noor, E.2
Savir, Y.3
Liebermeister, W.4
Davidi, D.5
Tawfik, D.S.6
Milo, R.7
-
53
-
-
0035875063
-
Biochemical analysis of mutations in palmitoyl-protein thioesterase causing infantile and late-onset forms of neuronal ceroid lipofuscinosis
-
Das, A. K., Lu, J. Y., and Hofmann, S. L. (2001) Biochemical analysis of mutations in palmitoyl-protein thioesterase causing infantile and late-onset forms of neuronal ceroid lipofuscinosis Hum. Mol. Genet. 10, 1431-1439
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1431-1439
-
-
Das, A.K.1
Lu, J.Y.2
Hofmann, S.L.3
|