Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: Role of carboxylesterases 1 and 2

Chemical Research in Toxicology

Volumn 23, Issue 12, 2010, Pages 1890-1904

  Xie, Shuqi ^a   Borazjani, Abdolsamad ^a   Hatfield, M Jason ^b   Edwards, Carol C ^b   Potter, Philip M ^b   Ross, Matthew K ^a  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; ANANDAMIDE; ARACHIDONIC ACID; CARBOXYLESTERASE; CARBOXYLESTERASE 1; CARBOXYLESTERASE 2; ESTER DERIVATIVE; ESTERASE INHIBITOR; FATTY ACID AMIDASE; ORGANOPHOSPHATE INSECTICIDE; PARAOXON; PARATHION; PROSTAGLANDIN GLYCERYL ESTER; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLOGICAL ACTIVITY; CELL LYSATE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROLYSIS; IN VIVO STUDY; LIPID METABOLISM; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXYGENATION; PROTEIN DEPLETION; SIGNAL TRANSDUCTION; STEADY STATE;

AMIDOHYDROLASES; ARACHIDONIC ACIDS; CARBOXYLESTERASE; CARBOXYLIC ESTER HYDROLASES; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLYCERIDES; HUMANS; HYDROLYSIS; INSECTICIDES; LIPID METABOLISM; MACROPHAGES; MASS SPECTROMETRY; MONOCYTES; PARAOXON; POLYUNSATURATED ALKAMIDES; PROSTAGLANDINS; RECOMBINANT PROTEINS;

HARNESS; HUMAN ECHOVIRUS 1; MAMMALIA; RATTUS;

EID: 78650452903     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx1002194     Document Type: Article

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