Human recombinant palmitoyl-protein thioesterase-1 (PPT1) for preclinical evaluation of enzyme replacement therapy for infantile neuronal ceroid lipofuscinosis

Molecular Genetics and Metabolism

Volumn 99, Issue 4, 2010, Pages 374-378

  Lu, Jui Yun ^a,b   Hu, Jie ^b   Hofmann, Sandra L ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Batten disease; Enzyme replacement therapy; Infantile neuronal ceroid lipofuscinosis; Lysosomal storage disorder

Indexed keywords

HUMAN RECOMBINANT PALMITOYL PROTEIN THIOESTERASE 1; MANNOSE 6 PHOSPHATE; RECOMBINANT PROTEIN; SOMATOMEDIN B RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; ENZYME REPLACEMENT; HEART; INCUBATION TIME; INFANTILE NEURONAL CEROID LIPOFUSCINOSIS; KIDNEY; LIVER; LUNG; LYMPHOBLAST; MOUSE; NEURONAL CEROID LIPOFUSCINOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; SPLEEN;

ANIMALS; BRAIN; CHO CELLS; CRICETINAE; CRICETULUS; DRUG EVALUATION, PRECLINICAL; HUMANS; MALE; MICE; MICE, KNOCKOUT; NEURONAL CEROID-LIPOFUSCINOSES; RECOMBINANT PROTEINS; THIOLESTER HYDROLASES; TISSUE DISTRIBUTION;

CRICETULUS GRISEUS; MUS;

EID: 77649337157     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2009.12.002     Document Type: Article

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