Simulative and experimental investigation on the cleavage site that generates the soluble human LOX-1

Archives of Biochemistry and Biophysics

Volumn 540, Issue 1-2, 2013, Pages 9-18

  Biocca, Silvia ^a   Arcangeli, Tania ^a   Tagliaferri, Elisa ^a   Testa, Barbara ^a   Vindigni, Giulia ^a   Oteri, Francesco ^a   Giorgi, Alessandra ^b   Iacovelli, Federico ^a   Novelli, Giuseppe ^a   Desideri, Alessandro ^a   Falconi, Mattia ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Classical molecular dynamics simulation; Coiled coil structure; Molecular threading; NECK domain; Proteolytic cleavage; Soluble LOX 1

Indexed keywords

OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PROTEINASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; HUMAN; HYDROGEN BOND; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR RECOGNITION; NECK DOMAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; STRUCTURE ANALYSIS;

CLASSICAL MOLECULAR DYNAMICS SIMULATION; COILED-COIL STRUCTURE; MOLECULAR THREADING; NECK DOMAIN; PROTEOLYTIC CLEAVAGE; SOLUBLE LOX-1;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; HUMANS; HYDROGEN BONDING; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; REPRODUCIBILITY OF RESULTS; SCAVENGER RECEPTORS, CLASS E; SOLUBILITY; SOLVENTS; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 84887109623     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2013.10.001     Document Type: Article

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