Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant

BMC Structural Biology

Volumn 7, Issue , 2007, Pages

  Falconi, Mattia ^a   Biocca, Silvia ^a   Novelli, Giuseppe ^a,b   Desideri, Alessandro ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b Fondazione Livio Patrizi   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; LECTIN; MONOMER; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; TRYPTOPHAN; LOW DENSITY LIPOPROTEIN; OLR1 PROTEIN, HUMAN; OXIDIZED LOW DENSITY LIPOPROTEIN; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CORRELATION ANALYSIS; HUMAN; MOLECULAR DYNAMICS; MUTANT; MUTATION; PROTEIN BINDING; SIMULATION; STRUCTURE ANALYSIS; WILD TYPE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; HYDROGEN BOND; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ALANINE; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; LIPOPROTEINS, LDL; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; SCAVENGER RECEPTORS, CLASS E; TRYPTOPHAN;

EID: 38149137291     PISSN: None     EISSN: 14726807     Source Type: Journal    
DOI: 10.1186/1472-6807-7-73     Document Type: Article

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