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Volumn 44, Issue 3, 2008, Pages 561-570

The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization

Author keywords

Lectin like oxidized LDL receptor (LOX 1); LOXIN; oligomerization; oxidized LDL

Indexed keywords

LOXIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 40649099556     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2007.11.017     Document Type: Article
Times cited : (62)

References (30)
  • 1
    • 0036852824 scopus 로고    scopus 로고
    • Innate and acquired immunity in atherogenesis
    • Binder CJ, Chang MK, Shaw PX, Miller YI, Hartvigsen K, Dewan A, et al.Innate and acquired immunity in atherogenesis. Nat Med 2002;8:1218–1226
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1218-1226
    • Binder, C.J.1    Chang, M.K.2    Wigderson, A.3
  • 2
    • 0036853543 scopus 로고    scopus 로고
    • Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime
    • Steinberg D. Atherogenesis in perspective: hypercholesterolemia and inflammation as partners in crime. Nat Med 2002;8:1211–7.
    • (2002) Nature Medicine , vol.8 , Issue.11 , pp. 1211-1217
    • Steinberg, D.1
  • 3
    • 0035993485 scopus 로고    scopus 로고
    • LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: Implications in endothelial dysfunction and atherosclerosis
    • Chen M, Masaki T, Sawamura T. LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. Pharmacol Ther 2002;95:89–100.
    • (2002) Pharmacology and Therapeutics , vol.95 , Issue.1 , pp. 89-100
    • Chen, M.1    Masaki, T.2    Sawamura, T.3
  • 4
    • 29144488035 scopus 로고    scopus 로고
    • Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders
    • Metha JL, Chen J, Hermonat P, Romeo F, Novelli G. Lectin-like, oxidized low-density lipoprotein receptor-1 (LOX-1): a critical player in the development of atherosclerosis and related disorders. Cardiovascular Research 2006;69(1),pp:36–45.
    • (2006) Cardiovascular Research , vol.69 , Issue.1 , pp. 36-45
    • Metha, J.L.1    Chen, J.2    Hermonat, P.3    Romeo, F.4    Novelli, G.5
  • 5
    • 0035901582 scopus 로고    scopus 로고
    • Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes
    • Ehara S, Ueda M, Naruko T, Haze K, Itoh A, Otsuka M, et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes. Circulation 2001;103: 1955–60.
    • (2001) Circulation , vol.103 , Issue.15 , pp. 1955-1960
    • Ehara, S.1    Ueda, M.2    Naruko, T.3    Haze, K.4    Itoh, A.5    Otsuka, M.6
  • 6
  • 7
    • 0035871224 scopus 로고    scopus 로고
    • Conserved C-terminal residues within the lectin-like domain of LOX-1 are essential for oxidized low-density-lipoprotein binding
    • Chen M, Narumiya S, Masaki T, Sawamura T. Conserved C-terminal residues within the lectin-like domain of LOX-1 are essential for the oxidized low-density-lipoprotein binding. Biochem J 2001;355:289–96.
    • (2001) Biochemical Journal , vol.355 , Issue.2 , pp. 289-296
    • Chen, M.1    Narumiya, S.2    Masaki, T.3    Sawamura, T.4
  • 8
    • 0344099414 scopus 로고    scopus 로고
    • Xie Q, Matsunaga S, Shi X, Ogawa S, Niimi S,Wen Z, et al. Refolding and characterization of the functional ligand-binding domain of human lectinlike oxidized LDL receptor. Protein Expr Purif 2003;32:68–74
    • Xie Q, Matsunaga S, Shi X, Ogawa S, Niimi S,Wen Z, et al. Refolding and characterization of the functional ligand-binding domain of human lectinlike oxidized LDL receptor. Protein Expr Purif 2003;32:68–74
  • 9
    • 1242269763 scopus 로고    scopus 로고
    • Xie Q, Matsunaga S, Niimi S, Ogawa S, Tokuyasu K, Sakakibara Y, et al. Human lectin-like oxidized low-density lipoprotein receptor-1 functions as a dimer in living cells. DNA Cell Biol 2004;23:111–7.
    • Xie Q, Matsunaga S, Niimi S, Ogawa S, Tokuyasu K, Sakakibara Y, et al. Human lectin-like oxidized low-density lipoprotein receptor-1 functions as a dimer in living cells. DNA Cell Biol 2004;23:111–7
  • 10
    • 20444380998 scopus 로고    scopus 로고
    • Ohki I, Ishigaki T, Oyama T, Matsunaga S, Xie Q, Ohnishi-Kameyama M, et al. Crystal structure of human lectin-like, oxidized low-density lipoprotein receptor-1 ligand binding domain and its ligand recognition mode to ox-LDL. Structure 2005;13:905–17.
    • Ohki I, Ishigaki T, Oyama T, Matsunaga S, Xie Q, Ohnishi-Kameyama M, et al. Crystal structure of human lectin-like, oxidized low-density lipoprotein receptor-1 ligand binding domain and its ligand recognition mode to ox-LDL. Structure 2005;13:905–17..
  • 11
    • 17144362479 scopus 로고    scopus 로고
    • Park H, Adsit FG, Boyington JC. The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1. J Biol Chem 2005;280:13593–9.
    • Park H, Adsit FG, Boyington JC. The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1. J Biol Chem 2005;280:13593–9.
  • 12
    • 32244436423 scopus 로고    scopus 로고
    • Vohra RS, Murphy JE, Walker JH, Ponnambalam S, Vanniasinkam SH. Atherosclerosis and the lectin-like oxidized low-density lipoprotein scavenger receptor. Trends Cardiovasc Med 2006;16:60–4.
    • Vohra RS, Murphy JE, Walker JH, Ponnambalam S, Vanniasinkam SH. Atherosclerosis and the lectin-like oxidized low-density lipoprotein scavenger receptor. Trends Cardiovasc Med 2006;16:60–4.
  • 13
    • 9144244821 scopus 로고    scopus 로고
    • Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction
    • Mango R, Clementi F, Borgiani P, Forleo GB, Federici M, Contino G, et al. Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction. J Med Genet 2003;40:933–6.
    • (2003) Journal of Medical Genetics , vol.40 , Issue.12 , pp. 933-936
    • Mango, R.1    Clementi, F.2    Borgiani, P.3    Forleo, G.B.4    Federici, M.5    Contino, G.6
  • 14
    • 0038755651 scopus 로고    scopus 로고
    • Chen Q, Reis SE, Kammerer C, Craig WY, LaPierre SE, Zimmer EL, et al.Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1(LOX1) gene and the risk of coronary artery disease. Circulation 2003;107:3146–51.
    • Chen Q, Reis SE, Kammerer C, Craig WY, LaPierre SE, Zimmer EL, et al.Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1(LOX1) gene and the risk of coronary artery disease. Circulation 2003;107:3146–51.
  • 15
    • 22744450055 scopus 로고    scopus 로고
    • Mango R, Biocca S, Del Vecchio F, Clementi F, Sangiuolo F, Amati F, et al. In vivo and in vitro studies supports that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction. Circ Res 2005;97:152–8.
    • Mango R, Biocca S, Del Vecchio F, Clementi F, Sangiuolo F, Amati F, et al. In vivo and in vitro studies supports that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction. Circ Res 2005;97:152–8..
  • 16
    • 0033952543 scopus 로고    scopus 로고
    • Lener M, Horn IR, Cardinale A, Messina S, Nielsen UB, Rybak SM, et al. Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras. Eur J Biochem 2000;267:1196–205.
    • Lener M, Horn IR, Cardinale A, Messina S, Nielsen UB, Rybak SM, et al. Diverting a protein from its cellular location by intracellular antibodies. The case of p21Ras. Eur J Biochem 2000;267:1196–205.
  • 17
    • 12844260131 scopus 로고    scopus 로고
    • Cardinale A, Filesi I, Vetrugno V, Pocchiari M, Sy MS, Biocca S. Trapping prion protein in the endoplasmic reticulum impairs PrPc maturation and prevents PrPSc accumulation. J Biol Chem 2005;280:685–94.
    • Cardinale A, Filesi I, Vetrugno V, Pocchiari M, Sy MS, Biocca S. Trapping prion protein in the endoplasmic reticulum impairs PrPc maturation and prevents PrPSc accumulation. J Biol Chem 2005;280:685–94.
  • 18
    • 0023806075 scopus 로고    scopus 로고
    • Smith DB, Johnson KS. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 1988;67:31–40.
    • Smith DB, Johnson KS. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase. Gene 1988;67:31–40.
  • 19
    • 33644693775 scopus 로고    scopus 로고
    • Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs
    • Tentori L, Vergati M, Muzi A, Levati L, Ruffini F, Forini O. Generation of an immortalized human endothelial cell line as a model of neovascular proliferating endothelial cells to assess chemosensitivity to anticancer drugs. International Journal of Oncology 27(2),2005;pp:525–535.
    • (2005) International Journal of Oncology , vol.27 , Issue.2 , pp. 525-535
    • Tentori, L.1    Vergati, M.2    Muzi, A.3    Levati, L.4    Ruffini, F.5    Forini, O.6
  • 20
    • 0029165943 scopus 로고
    • Effects of Iron- and Hemoglobin-Loaded Human Monocyte–Derived Macrophages on Oxidation and Uptake of LDL
    • Yuan XM, Brunk UT, Olsson AG. Effects of iron- and haemoglobinloaded human monocyte derived macrophages on oxidation and uptake of LDL. Arterioscler Thromb Vasc Biol 1995;15:1345–51.
    • (1995) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.15 , Issue.9 , pp. 1345-1351
    • Yuan, X.M.1    Brunk, U.T.2    Olsson, A.G.3
  • 21
    • 85058493997 scopus 로고    scopus 로고
    • Sattler W, Bone P, Stocker R. Isolation of human VLDL, LDL, HDL and two HDL subclasses in the TL-100 tabletop centrifuge using the TLA- 100.4 rotor. Technical information Beckman; 1992.
    • Sattler W, Bone P, Stocker R. Isolation of human VLDL, LDL, HDL and two HDL subclasses in the TL-100 tabletop centrifuge using the TLA- 100.4 rotor. Technical information Beckman; 1992.
  • 22
    • 0027453262 scopus 로고    scopus 로고
    • Stephan ZF, Yurachek EC. Rapid fluorometric assay of LDL receptor activity by DiI-labeled LDL. J Lipid Res 1993;34:325–30.
    • Stephan ZF, Yurachek EC. Rapid fluorometric assay of LDL receptor activity by DiI-labeled LDL. J Lipid Res 1993;34:325–30.
  • 23
    • 0037454162 scopus 로고    scopus 로고
    • Li D,Williams V, Liu L, Chen H, Sawamura T, Romeo F, et al. Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia– reperfusion and its role in determination of apoptosis and left ventricular dysfunction. J Am Coll Cardiol 2003;41:1048–55.
    • Li D,Williams V, Liu L, Chen H, Sawamura T, Romeo F, et al. Expression of lectin-like oxidized low-density lipoprotein receptors during ischemia– reperfusion and its role in determination of apoptosis and left ventricular dysfunction. J Am Coll Cardiol 2003;41:1048–55.
  • 24
    • 0035032519 scopus 로고    scopus 로고
    • Shi X, Niimi S, Ohtani T, Machida S. Characterization of residues and sequences of the carbohydrate recognition domain required for cell surface localization and ligand binding of human lectin-like oxidized LDL receptor. J Cell Sci 2001;114:1273–82.
    • Shi X, Niimi S, Ohtani T, Machida S. Characterization of residues and sequences of the carbohydrate recognition domain required for cell surface localization and ligand binding of human lectin-like oxidized LDL receptor. J Cell Sci 2001;114:1273–82.
  • 25
    • 14644387575 scopus 로고    scopus 로고
    • Bulenger S, Marullo S, Bouvier M. Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation. Trends Pharmacol Sci 2005;26:131–7.
    • Bulenger S, Marullo S, Bouvier M. Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation. Trends Pharmacol Sci 2005;26:131–7.
  • 26
    • 33947259758 scopus 로고    scopus 로고
    • Lectin-like oxidized low-density lipoprotein receptor (LOX-1) functions as an oligomer and oligomerization is dependent on receptor density
    • Matsunaga S, Xie Q, Kumanu M, Niimi S, Sekizawa K, Sakakibara Y,et al. Lectin-like oxidized low-density lipoprotein receptor (LOX-1) functions as an oligomer and oligomerization is dependent on receptor density. Exp Cell Res 2007;313:1203–14.
    • (2007) Experimental Cell Research , vol.313 , Issue.6 , pp. 1203-1214
    • Matsunaga, S.1    Xie, Q.2    Kumanu, M.3
  • 27
    • 33745188916 scopus 로고    scopus 로고
    • Feng YH, Li X, Wang L, Zhou L, Gorodeski GI. A truncated P2X7 receptor variant (P2X 7-J) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization. J Biol Chem 2005;281:17228–37.
    • Feng YH, Li X, Wang L, Zhou L, Gorodeski GI. A truncated P2X7 receptor variant (P2X 7-J) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization. J Biol Chem 2005;281:17228–37
  • 28
    • 33748151475 scopus 로고    scopus 로고
    • Dominant-negative Lox-1 blocks homodimerization of wild-type Lox-1-induced cell proliferation through extracellular signal regulated kinase 1/2 activation
    • Tanigawa H, Miura S, Matsuo Y, Fujino M, Sawamura T, Saku K. Dominant-negative Lox-1 blocks homodimerization of wild-type Lox-1- induced cell proliferation through extracellular signal regulated kinase 1/2 activation. Hypertension 2006;48:294–300.
    • (2006) Hypertension , vol.48 , Issue.2 , pp. 294-230
    • Tanigawa, H.1    Miura, S.2    Matsuo, Y.3    Fujino, M.4    Sawamura, T.5    Saku, K.6
  • 29
    • 15044364239 scopus 로고    scopus 로고
    • Regulatory polymorphisms underlying complex disease traits
    • Knight JC. Regulatory polymorphisms underlying complex disease traits.J Mol Med 2005;83:97–109.
    • (2005) Journal of Molecular Medicine , vol.83 , Issue.2 , pp. 97-109
    • Knight, J.C.1
  • 30
    • 34250190986 scopus 로고    scopus 로고
    • Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet
    • Mehta JL, Sanada N, Hu CP, Chen J, Dandapat A, Sugawara F, et al.Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet. Circ Res 2007;100:1634–42.
    • (2001) Circulation Research , vol.100 , Issue.11 , pp. 1634-1642
    • Mehta, J.L.1    Sanada, N.2    Hu, C.P.3    Dandapat, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.