Key role of ERK1/2 molecular scaffolds in heart pathology

Cellular and Molecular Life Sciences

Volumn 70, Issue 21, 2013, Pages 4047-4054

  Tarone, Guido ^a   Sbroggiò, Mauro ^b   Brancaccio, Mara ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

Author keywords

Cardiac remodelling; ERK1 2 pathway; Intracellular signalling; Scaffold proteins

Indexed keywords

BETA ARRESTIN; DUAL SPECIFICITY TYROSINE PHOSPHORYLATED AND REGULATED KINASE 1A; FOUR AND A HALF LIM DOMAIN PROTEIN 1; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE INTERACTING PROTEIN 1; IQ MOTIF CONTAINING GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; KINASE SUPPRESSOR OF RAS 1; LIM PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE ORGANISER 1; MITOGEN ACTIVATED PROTEIN KINASE PARTNER 1; MOLECULAR SCAFFOLD; PAXILLIN; PROTEIN MDM2; RAF PROTEIN; SCAFFOLD PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ENZYME ACTIVATION; HEART DISEASE; HUMAN; NONHUMAN; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; ARRESTINS; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HEART; HEART FAILURE; HUMANS; MAP KINASE SIGNALING SYSTEM; MICE; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; RAF KINASES; SIGNAL TRANSDUCTION;

EID: 84887027261     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-013-1321-5     Document Type: Review

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