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Volumn 699, Issue , 2011, Pages 179-202

Phospho Flow Cytometry Methods for the Analysis of Kinase Signaling in Cell Lines and Primary Human Blood Samples

Author keywords

Cell based; Cytokine; Drug discovery; Phospho flow cytometry; Primary cells; Signaling

Indexed keywords

ANTIBODY; FLUORESCENT DYE; MEMBRANE PROTEIN; PHOSPHOPROTEIN; PHOSPHOTRANSFERASE;

EID: 79956275308     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61737-950-5_9     Document Type: Chapter
Times cited : (69)

References (13)
  • 1
    • 1642463417 scopus 로고    scopus 로고
    • Analysis of protein phosphorylation and cellular signaling events by flow cytometry: Techniques and clinical applications
    • Krutzik, P. O., Irish, J. M., Nolan, G. P., and Perez, O. D. (2004) Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Clin Immunol 110, 206–21.
    • (2004) Clin Immunol , vol.110 , pp. 206-221
    • Krutzik, P.O.1    Irish, J.M.2    Nolan, G.P.3    Perez, O.D.4
  • 2
    • 77950405478 scopus 로고    scopus 로고
    • Single-cell phospho-protein analysis by flow cytometry. Curr Protoc Immunol Chapter 8
    • Schulz, K. R., Danna, E. A., Krutzik, P. O., and Nolan, G. P. (2007) Single-cell phospho-protein analysis by flow cytometry. Curr Protoc Immunol Chapter 8, Unit 8.17.
    • (2007) Unit , vol.8 , pp. 17
    • Schulz, K.R.1    Danna, E.A.2    Krutzik, P.O.3    Nolan, G.P.4
  • 3
    • 67649229170 scopus 로고    scopus 로고
    • The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals
    • Hotson, A. N., Hardy, J. W., Hale, M. B., Contag, C. H., and Nolan, G. P. (2009) The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. J Immunol 182, 7558–68.
    • (2009) J Immunol , vol.182 , pp. 7558-7568
    • Hotson, A.N.1    Hardy, J.W.2    Hale, M.B.3    Contag, C.H.4    Nolan, G.P.5
  • 5
    • 23444432362 scopus 로고    scopus 로고
    • Characterization of the murine immunological signaling network with phosphospecific flow cytometry
    • Krutzik, P. O., Hale, M. B., and Nolan, G. P. (2005) Characterization of the murine immunological signaling network with phosphospecific flow cytometry. J Immunol 175, 2366–73.
    • (2005) J Immunol , vol.175 , pp. 2366-2373
    • Krutzik, P.O.1    Hale, M.B.2    Nolan, G.P.3
  • 6
    • 69449090795 scopus 로고    scopus 로고
    • Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus ery-thematosus
    • Hale M. B., Krutzik, P. O., Samra, S. S., Crane, J. M., and Nolan, G. P. (2009) Stage dependent aberrant regulation of cytokine-STAT signaling in murine systemic lupus ery-thematosus. PLoS One 4, e6756.
    • (2009) Plos One , vol.4
    • Hale, M.B.1    Krutzik, P.O.2    Samra, S.S.3    Crane, J.M.4    Nolan, G.P.5
  • 7
    • 33751195937 scopus 로고    scopus 로고
    • Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells
    • Irish, J. M., Czerwinski, D. K., Nolan, G. P., and Levy, R. (2006) Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Blood 108, 3135–42.
    • (2006) Blood , vol.108 , pp. 3135-3142
    • Irish, J.M.1    Czerwinski, D.K.2    Nolan, G.P.3    Levy, R.4
  • 9
    • 33644833555 scopus 로고    scopus 로고
    • Mapping normal and cancer cell signalling networks: Towards single-cell proteomics
    • Irish, J. M., Kotecha, N., and Nolan, G. P. (2006) Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Nat Rev Cancer 6, 146–55.
    • (2006) Nat Rev Cancer , vol.6 , pp. 146-155
    • Irish, J.M.1    Kotecha, N.2    Nolan, G.P.3
  • 10
    • 38349043669 scopus 로고    scopus 로고
    • High-content single-cell drug screening with phosphospecific flow cytometry
    • Krutzik, P. O., Crane, J. M., Clutter, M. R., and Nolan, G. P. (2008) High-content single-cell drug screening with phosphospecific flow cytometry. Nat Chem Biol 4, 132–42.
    • (2008) Nat Chem Biol , vol.4 , pp. 132-142
    • Krutzik, P.O.1    Crane, J.M.2    Clutter, M.R.3    Nolan, G.P.4
  • 11
    • 33646029128 scopus 로고    scopus 로고
    • Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling
    • Krutzik, P. O. and Nolan, G. P. (2006) Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Nat Methods 3, 361–8.
    • (2006) Nat Methods , vol.3 , pp. 361-368
    • Krutzik, P.O.1    Nolan, G.P.2
  • 12
    • 0346244001 scopus 로고    scopus 로고
    • Intracellular phospho-protein staining techniques for flow cytometry: Monitoring single cell signaling events
    • Krutzik, P. O. and Nolan, G. P. (2003) Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Cytometry A 55, 61–70.
    • (2003) Cytometry A , vol.55 , pp. 61-70
    • Krutzik, P.O.1    Nolan, G.P.2
  • 13
    • 23444446774 scopus 로고    scopus 로고
    • Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry
    • Krutzik, P. O., Clutter, M. R., and Nolan, G. P. (2005) Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. J Immunol 175, 2357–65.
    • (2005) J Immunol , vol.175 , pp. 2357-2365
    • Krutzik, P.O.1    Clutter, M.R.2    Nolan, G.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.