-
1
-
-
0034733899
-
Base excision repair of DNA in mammalian cells
-
DOI 10.1016/S0014-5793(00)01674-4, PII S0014579300016744
-
Krokan, H. E., Nilsen, H., Skorpen, F., Otterlei, M. and Slupphaug, G. (2000) Base excision repair of DNA in mammalian cells. FEBS Lett. 476, 73-77 (Pubitemid 30394654)
-
(2000)
FEBS Letters
, vol.476
, Issue.1-2
, pp. 73-77
-
-
Krokan, H.E.1
Nilsen, H.2
Skorpen, F.3
Otterlei, M.4
Slupphaug, G.5
-
2
-
-
33847663262
-
The enigmatic thymine DNA glycosylase
-
DOI 10.1016/j.dnarep.2006.10.013, PII S1568786406003223, Repair of small base lesions in DNA-from molecular biology to phenotype
-
Cortazar, D., Kunz, C., Saito, Y., Steinacher, R. and Schar, P. (2007) The enigmatic thymine DNA glycosylase. DNA Repair 6, 489-504 (Pubitemid 46357052)
-
(2007)
DNA Repair
, vol.6
, Issue.4
, pp. 489-504
-
-
Cortazar, D.1
Kunz, C.2
Saito, Y.3
Steinacher, R.4
Schar, P.5
-
3
-
-
33749171576
-
Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability
-
DOI 10.1021/ja0634829
-
Bennett, M. T., Rodgers, M. T., Hebert, A. S., Ruslander, L. E., Eisele, L. and Drohat, A. C. (2006) Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability. J. Am. Chem. Soc. 128, 12510-12519 (Pubitemid 44476642)
-
(2006)
Journal of the American Chemical Society
, vol.128
, Issue.38
, pp. 12510-12519
-
-
Bennett, M.T.1
Rodgers, M.T.2
Hebert, A.S.3
Ruslander, L.E.4
Eisele, L.5
Drohat, A.C.6
-
4
-
-
0035233134
-
Thymine DNA glycosylase
-
PII S0079660301681030, Base Excesion Repair
-
Hardeland, U., Bentele, M., Lettieri, T., Steinacher, R., Jiricny, J. and Schar, P. (2001) Thymine DNA glycosylase. Prog. Nucleic Acid Res. Mol. Biol. 68, 235-253 (Pubitemid 33805740)
-
(2001)
Progress in Nucleic Acid Research and Molecular Biology
, vol.68
, pp. 235-253
-
-
Hardeland, U.1
Bentele, M.2
Lettieri, T.3
Steinacher, R.4
Jiricny, J.5
Schar, P.6
-
5
-
-
0038074420
-
The versatile thymine DNA-glycosylase: A comparative characterization of the human, Drosophila and fission yeast orthologs
-
DOI 10.1093/nar/gkg344
-
Hardeland, U., Bentele, M., Jiricny, J. and Schar, P. (2003) The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. Nucleic Acids Res. 31, 2261-2271 (Pubitemid 37442093)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.9
, pp. 2261-2271
-
-
Hardeland, U.1
Bentele, M.2
Jiricny, J.3
Schar, P.4
-
6
-
-
34948854919
-
Excision of 5-halogenated uracils by human thymine DNA glycosylase: Robust activity for DNA contexts other than CpG
-
DOI 10.1074/jbc.M704253200
-
Morgan, M. T., Bennett, M. T. and Drohat, A. C. (2007) Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG. J. Biol. Chem. 282, 27578-27586 (Pubitemid 47529476)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.38
, pp. 27578-27586
-
-
Morgan, M.T.1
Bennett, M.T.2
Drohat, A.C.3
-
7
-
-
0023853921
-
The CpG dinucleotide and human genetic disease
-
Cooper, D. N. and Youssoufian, H. (1988) The CpG dinucleotide and human genetic disease. Hum. Genet. 78, 151-155 (Pubitemid 18069872)
-
(1988)
Human Genetics
, vol.78
, Issue.2
, pp. 151-155
-
-
Cooper, D.N.1
Youssoufian, H.2
-
8
-
-
43049105333
-
Demethylation of (cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development
-
Patra, S. K., Patra, A., Rizzi, F., Ghosh, T. C. and Bettuzzi, S. (2008) Demethylation of (cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development. Cancer Metastasis Rev. 27, 315-334
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 315-334
-
-
Patra, S.K.1
Patra, A.2
Rizzi, F.3
Ghosh, T.C.4
Bettuzzi, S.5
-
9
-
-
79951810964
-
Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
-
Cortazar, D., Kunz, C., Selfridge, J., Lettieri, T., Saito, Y., MacDougall, E., Wirz, A., Schuermann, D., Jacobs, A. L., Siegrist, F. et al. (2011) Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature 470, 419-423
-
(2011)
Nature
, vol.470
, pp. 419-423
-
-
Cortazar, D.1
Kunz, C.2
Selfridge, J.3
Lettieri, T.4
Saito, Y.5
MacDougall, E.6
Wirz, A.7
Schuermann, D.8
Jacobs, A.L.9
Siegrist, F.10
-
10
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino, S., Xu, J., Sannai, M., Moore, R., Caretti, E., Cigliano, A., Le Coz, M., Devarajan, K., Wessels, A., Soprano, D. et al. (2011) Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146, 67-79
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wessels, A.9
Soprano, D.10
-
11
-
-
80052933429
-
DNA demethylation dynamics
-
Bhutani, N., Burns, D. M. and Blau, H. M. (2011) DNA demethylation dynamics. Cell 146, 866-872
-
(2011)
Cell
, vol.146
, pp. 866-872
-
-
Bhutani, N.1
Burns, D.M.2
Blau, H.M.3
-
12
-
-
79955538247
-
Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
-
Guo, J. U., Su, Y., Zhong, C., Ming, G. L. and Song, H. (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell 145, 423-434
-
(2011)
Cell
, vol.145
, pp. 423-434
-
-
Guo, J.U.1
Su, Y.2
Zhong, C.3
Ming, G.L.4
Song, H.5
-
13
-
-
80052495940
-
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
-
He, Y. F., Li, B. Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, L. et al. (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science 333, 1303-1307
-
(2011)
Science
, vol.333
, pp. 1303-1307
-
-
He, Y.F.1
Li, B.Z.2
Li, Z.3
Liu, P.4
Wang, Y.5
Tang, Q.6
Ding, J.7
Jia, Y.8
Chen, Z.9
Li, L.10
-
14
-
-
77956637544
-
DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC
-
Rai, K., Sarkar, S., Broadbent, T. J., Voas, M., Grossmann, K. F., Nadauld, L. D., Dehghanizadeh, S., Hagos, F. T., Li, Y., Toth, R. K. et al. (2010) DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell 142, 930-942
-
(2010)
Cell
, vol.142
, pp. 930-942
-
-
Rai, K.1
Sarkar, S.2
Broadbent, T.J.3
Voas, M.4
Grossmann, K.F.5
Nadauld, L.D.6
Dehghanizadeh, S.7
Hagos, F.T.8
Li, Y.9
Toth, R.K.10
-
15
-
-
77956095231
-
Active DNA demethylation: Many roads lead to Rome
-
Wu, S. C. and Zhang, Y. (2010) Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol. 11, 607-620
-
(2010)
Nat. Rev. Mol. Cell Biol
, vol.11
, pp. 607-620
-
-
Wu, S.C.1
Zhang, Y.2
-
16
-
-
80053917872
-
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: Potential implications for active demethylation of CpG sites
-
Maiti, A. and Drohat, A. C. (2011) Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J. Biol. Chem. 286, 35334-35338
-
(2011)
J. Biol. Chem
, vol.286
, pp. 35334-35338
-
-
Maiti, A.1
Drohat, A.C.2
-
17
-
-
0035161816
-
Functional interactions and signaling properties of mammalian DNA mismatch repair proteins
-
DOI 10.1038/sj.cdd.4400948
-
Bellacosa, A. (2001) Functional interactions and signaling properties of mammalian DNA mismatch repair proteins. Cell Death. Differ. 8, 1076-1092 (Pubitemid 33061825)
-
(2001)
Cell Death and Differentiation
, vol.8
, Issue.11
, pp. 1076-1092
-
-
Bellacosa, A.1
-
18
-
-
0036184090
-
Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription
-
DOI 10.1016/S1097-2765(02)00453-7
-
Tini, M., Benecke, A., Um, S. J., Torchia, J., Evans, R. M. and Chambon, P. (2002) Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol. Cell 9, 265-277 (Pubitemid 34195553)
-
(2002)
Molecular Cell
, vol.9
, Issue.2
, pp. 265-277
-
-
Tini, M.1
Benecke, A.2
Um, S.-J.3
Torchia, J.4
Evans, R.M.5
Chambon, P.6
-
19
-
-
35549003626
-
The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase
-
DOI 10.1093/nar/gkm678
-
Guan, X., Madabushi, A., Chang, D.-Y., Fitzgerald, M. E., Shi, G., Drohat, A. C. and Lu, A-L. (2007) The human checkpoint sensor Rad9-Rad1-Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase. Nucleic Acids Res. 35, 6207-6218 (Pubitemid 350018582)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.18
, pp. 6207-6218
-
-
Guan, X.1
Madabushi, A.2
Chang, D.-Y.3
Fitzgerald, M.E.4
Shi, G.5
Drohat, A.C.6
Lu, A.-L.7
-
20
-
-
17144410054
-
Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation
-
Steinacher, R. and Schar, P. (2005) Functionality of human thymine DNA glycosylase requires SUMO-regulated changes in protein conformation. Curr. Biol. 15, 616-623
-
(2005)
Curr. Biol
, vol.15
, pp. 616-623
-
-
Steinacher, R.1
Schar, P.2
-
21
-
-
77950347722
-
Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase
-
Mohan, R. D., Litchfield, D. W., Torchia, J. and Tini, M. (2010) Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase. Nucleic Acids Res. 38, 1135-1148
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 1135-1148
-
-
Mohan, R.D.1
Litchfield, D.W.2
Torchia, J.3
Tini, M.4
-
23
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
DOI 10.1146/annurev.biochem.73.011303.073651
-
Blander, G. and Guarente, L. (2004) The Sir2 family of protein deacetylases. Annu. Rev. Biochem. 73, 417-435 (Pubitemid 39050375)
-
(2004)
Annual Review of Biochemistry
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
24
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
DOI 10.1042/BJ20070140
-
Michan, S. and Sinclair, D. (2007) Sirtuins in mammals: insights into their biological function. Biochem. J. 404, 1-13 (Pubitemid 46788079)
-
(2007)
Biochemical Journal
, vol.404
, Issue.1
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
25
-
-
67651210858
-
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly (ADP-ribose) polymerase 1
-
Rajamohan, S. B., Pillai, V. B., Gupta, M., Sundaresan, N. R., Birukov, K. G., Samant, S., Hottiger, M. O. and Gupta, M. P. (2009) SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly (ADP-ribose) polymerase 1. Mol. Cell Biol. 29, 4116-4129
-
(2009)
Mol. Cell Biol
, vol.29
, pp. 4116-4129
-
-
Rajamohan, S.B.1
Pillai, V.B.2
Gupta, M.3
Sundaresan, N.R.4
Birukov, K.G.5
Samant, S.6
Hottiger, M.O.7
Gupta, M.P.8
-
26
-
-
77950351604
-
SIRT1 deacetylates APE1 and regulates cellular base excision repair
-
Yamamori, T., De Ricco, J., Naqvi, A., Hoffman, T. A., Mattagajasingh, I., Kasuno, K., Jung, S. B., Kim, C. S. and Irani, K. (2010) SIRT1 deacetylates APE1 and regulates cellular base excision repair. Nucleic Acids Res. 38, 832-845
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 832-845
-
-
Yamamori, T.1
De Ricco, J.2
Naqvi, A.3
Hoffman, T.A.4
Mattagajasingh, I.5
Kasuno, K.6
Jung, S.B.7
Kim, C.S.8
Irani, K.9
-
27
-
-
77952876986
-
Protein deacetylation by SIRT1: An emerging key post-translational modification in metabolic regulation
-
Yu, J. and Auwerx, J. (2010) Protein deacetylation by SIRT1: an emerging key post-translational modification in metabolic regulation. Pharmacol. Res. 62, 35-41
-
(2010)
Pharmacol. Res
, vol.62
, pp. 35-41
-
-
Yu, J.1
Auwerx, J.2
-
28
-
-
34250897968
-
SIRT1 regulates the function of the nijmegen breakage syndrome protein
-
DOI 10.1016/j.molcel.2007.05.029, PII S1097276507003309
-
Yuan, Z., Zhang, X., Sengupta, N., Lane, W. S. and Seto, E. (2007) SIRT1 regulates the function of the Nijmegen breakage syndrome protein. Mol. Cell 27, 149-162 (Pubitemid 46991383)
-
(2007)
Molecular Cell
, vol.27
, Issue.1
, pp. 149-162
-
-
Yuan, Z.1
Zhang, X.2
Sengupta, N.3
Lane, W.S.4
Seto, E.5
-
29
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer, P., Michan, S., McVay, M., Mostoslavsky, R., Vann, J., Park, S. K., Hartlerode, A., Stegmuller, J., Hafner, A., Loerch, P. et al. (2008) SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 135, 907-918
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
-
30
-
-
27244435939
-
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress
-
DOI 10.1016/j.cmet.2005.06.007, PII S1550413105001725
-
Chua, K. F., Mostoslavsky, R., Lombard, D. B., Pang, W. W., Saito, S., Franco, S., Kaushal, D., Cheng, H. L., Fischer, M. R., Stokes, N. et al. (2005) Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab. 2, 67-76 (Pubitemid 43239826)
-
(2005)
Cell Metabolism
, vol.2
, Issue.1
, pp. 67-76
-
-
Chua, K.F.1
Mostoslavsky, R.2
Lombard, D.B.3
Pang, W.W.4
Saito, S.5
Franco, S.6
Kaushal, D.7
Cheng, H.-L.8
Fischer, M.R.9
Stokes, N.10
Murphy, M.M.11
Appella, E.12
Alt, F.W.13
-
31
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
Wang, R. H., Sengupta, K., Li, C., Kim, H. S., Cao, L., Xiao, C., Kim, S., Xu, X., Zheng, Y., Chilton, B. et al. (2008) Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14, 312-323
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
Kim, H.S.4
Cao, L.5
Xiao, C.6
Kim, S.7
Xu, X.8
Zheng, Y.9
Chilton, B.10
-
32
-
-
62749133315
-
SIRT1, is it a tumor promoter or tumor suppressor?
-
Deng, C. X. (2009) SIRT1, is it a tumor promoter or tumor suppressor? Int. J. Biol. Sci. 5, 147-152
-
(2009)
Int. J. Biol. Sci
, vol.5
, pp. 147-152
-
-
Deng, C.X.1
-
33
-
-
79955469653
-
Sirtuin 1 in malignant transformation: Friend or foe?
-
Fang, Y. and Nicholl, M. B. (2011) Sirtuin 1 in malignant transformation: friend or foe? Cancer Lett. 306, 10-14
-
(2011)
Cancer Lett
, vol.306
, pp. 10-14
-
-
Fang, Y.1
Nicholl, M.B.2
-
34
-
-
67650563916
-
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
-
Kabra, N., Li, Z., Chen, L., Li, B., Zhang, X., Wang, C., Yeatman, T., Coppola, D. and Chen, J. (2009) SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J. Biol. Chem. 284, 18210-18217
-
(2009)
J. Biol. Chem
, vol.284
, pp. 18210-18217
-
-
Kabra, N.1
Li, Z.2
Chen, L.3
Li, B.4
Zhang, X.5
Wang, C.6
Yeatman, T.7
Coppola, D.8
Chen, J.9
-
35
-
-
0028825742
-
DNA determinants and substrate specificities of Escherichia coliMutY
-
Lu, A-L., Tsai-Wu, J.-J. and Cillo, J. (1995) DNA determinants and substrate specificities of Escherichia coliMutY. J. Biol. Chem. 270, 23582-23588
-
(1995)
J. Biol. Chem
, vol.270
, pp. 23582-23588
-
-
Lu, A.-L.1
Tsai-Wu, J.-J.2
Cillo, J.3
-
36
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
DOI 10.1073/pnas.1934713100
-
Cheng, H. L., Mostoslavsky, R., Saito, S., Manis, J. P., Gu, Y., Patel, P., Bronson, R., Appella, E., Alt, F. W. and Chua, K. F. (2003) Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Sci. U. S. A. 100, 10794-10799 (Pubitemid 37140107)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.19
, pp. 10794-10799
-
-
Cheng, H.-L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
37
-
-
57749097697
-
Coordinating the initial steps of base excision repair. Apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex
-
Fitzgerald, M. E. and Drohat, A. C. (2008) Coordinating the initial steps of base excision repair. Apurinic/apyrimidinic endonuclease 1 actively stimulates thymine DNA glycosylase by disrupting the product complex. J. Biol. Chem. 283, 32680-32690
-
(2008)
J. Biol. Chem
, vol.283
, pp. 32680-32690
-
-
Fitzgerald, M.E.1
Drohat, A.C.2
-
38
-
-
0032951710
-
Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1
-
DOI 10.1074/jbc.274.1.67
-
Waters, T. R., Gallinari, P., Jiricny, J. and Swann, P. F. (1999) Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1. J. Biol. Chem. 274, 67-74 (Pubitemid 29035031)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.1
, pp. 67-74
-
-
Waters, T.R.1
Gallinari, P.2
Jiricnyl, J.3
Swann, P.F.4
-
39
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis, M. C. and Sinclair, D. A. (2010) Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol. 5, 253-295
-
(2010)
Annu. Rev. Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
40
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
DOI 10.1016/j.cell.2005.11.044, PII S0092867406000493
-
Mostoslavsky, R., Chua, K. F., Lombard, D. B., Pang, W. W., Fischer, M. R., Gellon, L., Liu, P., Mostoslavsky, G., Franco, S., Murphy, M. M. et al. (2006) Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124, 315-329 (Pubitemid 43121980)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.-L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
-
41
-
-
33645221885
-
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage
-
Solomon, J. M., Pasupuleti, R., Xu, L., McDonagh, T., Curtis, R., Di Stefano, P. S. and Huber, L. J. (2006) Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol. Cell Biol. 26, 28-38
-
(2006)
Mol. Cell Biol
, vol.26
, pp. 28-38
-
-
Solomon, J.M.1
Pasupuleti, R.2
Xu, L.3
McDonagh, T.4
Curtis, R.5
Di Stefano, P.S.6
Huber, L.J.7
-
42
-
-
77955501963
-
SIRT1 regulates UV-induced DNA repair through deacetylating XPA
-
Fan, W. and Luo, J. (2010) SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol. Cell 39, 247-258
-
(2010)
Mol. Cell
, vol.39
, pp. 247-258
-
-
Fan, W.1
Luo, J.2
-
43
-
-
78649633708
-
Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells
-
Akao, Y., Noguchi, S., Iio, A., Kojima, K., Takagi, T. and Naoe, T. (2011) Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett. 300, 197-204
-
(2011)
Cancer Lett
, vol.300
, pp. 197-204
-
-
Akao, Y.1
Noguchi, S.2
Iio, A.3
Kojima, K.4
Takagi, T.5
Naoe, T.6
-
44
-
-
33847647624
-
SIRT1 promotes DNA repair activity and deacetylation of Ku70
-
Jeong, J., Juhn, K., Lee, H., Kim, S. H., Min, B. H., Lee, K. M., Cho, M. H., Park, G. H. and Lee, K. H. (2007) SIRT1 promotes DNA repair activity and deacetylation of Ku70. Exp. Mol. Med. 39, 8-13 (Pubitemid 46356001)
-
(2007)
Experimental and Molecular Medicine
, vol.39
, Issue.1
, pp. 8-13
-
-
Jeong, J.1
Juhn, K.2
Lee, H.3
Kim, S.-H.4
Min, B.-H.5
Lee, K.-M.6
Cho, M.-H.7
Park, G.-H.8
Lee, K.-H.9
-
45
-
-
0038387494
-
5-Fluorouracil: Mechanisms of action and clinical strategies
-
DOI 10.1038/nrc1074
-
Longley, D. B., Harkin, D. P. and Johnston, P. G. (2003) 5-Fluorouracil: mechanisms of action and clinical strategies. Nat. Rev. Cancer 3, 330-338 (Pubitemid 37328853)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.5
, pp. 330-338
-
-
Longley, D.B.1
Harkin, D.P.2
Johnston, P.G.3
-
46
-
-
65949089155
-
Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil
-
Kunz, C., Focke, F., Saito, Y., Schuermann, D., Lettieri, T., Selfridge, J. and Schar, P. (2009) Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil. PLoS Biol. 7, e91
-
(2009)
PLoS Biol
, vol.7
-
-
Kunz, C.1
Focke, F.2
Saito, Y.3
Schuermann, D.4
Lettieri, T.5
Selfridge, J.6
Schar, P.7
-
47
-
-
77649104794
-
Reprogramming towards pluripotency requires AID-dependent DNA demethylation
-
Bhutani, N., Brady, J. J., Damian, M., Sacco, A., Corbel, S. Y. and Blau, H. M. (2010) Reprogramming towards pluripotency requires AID-dependent DNA demethylation. Nature 463, 1042-1047
-
(2010)
Nature
, vol.463
, pp. 1042-1047
-
-
Bhutani, N.1
Brady, J.J.2
Damian, M.3
Sacco, A.4
Corbel, S.Y.5
Blau, H.M.6
-
48
-
-
40449104358
-
Transient cyclical methylation of promoter DNA
-
DOI 10.1038/nature06640, PII NATURE06640
-
Kangaspeska, S., Stride, B., Metivier, R., Polycarpou-Schwarz, M., Ibberson, D., Carmouche, R. P., Benes, V., Gannon, F. and Reid, G. (2008) Transient cyclical methylation of promoter DNA. Nature 452, 112-115 (Pubitemid 351355094)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 112-115
-
-
Kangaspeska, S.1
Stride, B.2
Metivier, R.3
Polycarpou-Schwarz, M.4
Ibberson, D.5
Carmouche, R.P.6
Benes, V.7
Gannon, F.8
Reid, G.9
-
49
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
DOI 10.1038/nature06544, PII NATURE06544
-
Metivier, R., Gallais, R., Tiffoche, C., Le Peron, C., Jurkowska, R. Z., Carmouche, R. P., Ibberson, D., Barath, P., Demay, F., Reid, G. et al. (2008) Cyclical DNA methylation of a transcriptionally active promoter. Nature 452, 45-50 (Pubitemid 351355084)
-
(2008)
Nature
, vol.452
, Issue.7183
, pp. 45-50
-
-
Metivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Peron, C.4
Jurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
Reid, G.10
Benes, V.11
Jeltsch, A.12
Gannon, F.13
Salbert, G.14
-
50
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
DOI 10.1074/jbc.M407695200
-
Morgan, H. D., Dean, W., Coker, H. A., Reik, W. and Petersen-Mahrt, S. K. (2004) Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J. Biol. Chem. 279, 52353-52360 (Pubitemid 39656611)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
51
-
-
33847065486
-
The epigenomics of cancer
-
DOI 10.1016/j.cell.2007.01.029, PII S0092867407001274
-
Jones, P. A. and Baylin, S. B. (2007) The epigenomics of cancer. Cell 128, 683-692 (Pubitemid 46273572)
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
|