COP1 targets C/EBPα for degradation and induces acute myeloid leukemia via Trib1

Blood

Volumn 122, Issue 10, 2013, Pages 1750-1760

  Yoshida, Akihiro ^a   Kato, Jun Ya ^a   Nakamae, Ikuko ^a   Yoneda Kato, Noriko ^a  

^a NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; ONCOPROTEIN; TRIB1 PROTEIN; UBIQUITIN PROTEIN LIGASE COP1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; GRANULOCYTE COLONY STIMULATING FACTOR; MUTANT PROTEIN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; RFWD2 PROTEIN, MOUSE; SIGNAL PEPTIDE; TRIB1 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ACUTE MYELOID LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; CARCINOGENESIS; CELL DIFFERENTIATION; CONTROLLED STUDY; DEGRADATION; DOWN REGULATION; ENZYME ACTIVITY; HEMATOPOIETIC CELL; IN VIVO STUDY; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ACUTE GRANULOCYTIC LEUKEMIA; ALTERNATIVE RNA SPLICING; ANIMAL; C57BL MOUSE; CELL STRAIN 3T3; CELL STRAIN HEK293; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; GRANULOCYTE; HUMAN; METABOLISM; MUTATION; PATHOLOGY; PROTEIN DEGRADATION;

ALTERNATIVE SPLICING; ANIMALS; BONE MARROW TRANSPLANTATION; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; CELL DIFFERENTIATION; GRANULOCYTE COLONY-STIMULATING FACTOR; GRANULOCYTES; HEK293 CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, INBRED C57BL; MUTANT PROTEINS; MUTATION; NIH 3T3 CELLS; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES;

EID: 84886461020     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-476101     Document Type: Article

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