Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis

Blood

Volumn 109, Issue 9, 2007, Pages 3998-4005

  Jin, Guang ^a   Yamazaki, Yukari ^a   Takuwa, Miki ^a   Takahara, Tomoko ^a   Kaneko, Keiko ^a   Kuwata, Takeshi ^a   Miyata, Satoshi ^b   Nakamura, Takuro ^a  

^a CANCER INSTITUTE   (Japan)

^b CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; EVI 1 GENE; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE OVEREXPRESSION; GENE SEQUENCE; HOXA 9 GENE; LEUKEMOGENESIS; MALE; MEIS 1 GENE; MUTAGENESIS; MYELOID LEUKEMIA; NONHUMAN; NUCLEOTIDE SEQUENCE; ONCOGENE; PRIORITY JOURNAL; RETROVIRUS; TRIB 1 GENE; UPREGULATION;

EID: 34247391073     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-08-041202     Document Type: Article

References (41)

1. Malumbres M, Barbacid M. To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer. 2001;1:222-231.
2. Magli MC, Largman C, Lawrence HJ. Effects of HOX homeobox genes in blood cell differentiation. J Cell Physiol. 1997;173:168-177.
3. Nakamura T, Largaespada DA, Shaughnessy JD, Jenkins NA, Copeland NG. Cooperative activation of Hoxa and Pbx1-related genes in murine myeloid leukemias. Nat Genet. 1996;12:149-153.
4. Borrow J, Shearman AM, Stanton VP, et al. The t(7;11)(p15;p15) tanslocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9. Nat Genet. 1996;12:159-167.
5. Nakamura T, Largaespada DA, Lee MP, et al. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukemia. Nat Genet. 1996;12:154-158.
6. Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J. 1998;17:3714-3725.
7. Kroon E, Thorsteinsdottir U, Mayotte N, Nakamura T, Sauvageau G. NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. EMBO J. 2001;20:350-361.
8. Wang GG, Pasillas MP, Kamps MP. Meis1 programs transcription of FLT3 and cancer stem cell character, using a mechanism that requires interaction with Pbx and a novel function of the Meis1 C-terminus. Blood. 2005;106:254-264.
9. Palmqvist L, Argilopoulos B, Pineault N, et al. The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia. Blood. 2006;108:1030-1036.
10. Wang GG, Pasillas MP, Kamps MP. Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes. Mol Cell Biol. 2006;26:3902-3916.
11. Mikkers H, Berns A. Retroviral insertional mutagenesis: tagging cancer pathways. Adv Cancer Res. 2003;88:53-99.
12. Nakamura T. Retroviral insertional mutagenesis identifies oncogene cooperation. Cancer Sci. 2005;96:7-12.
13. Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature. 2003;423:255-260.
14. Fujino T, Yamazaki Y, Largaespada DA, et al. Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes. Exp Hematol. 2001;29:856-863.
15. Morita S, Kojima T, Kitamura T. Plat-E: and efficient and stable system for transient packaging of retroviruses. Gene Ther. 2000;7:1063-1066.
16. Kogan SC, Ward JM, Anver MR, et al. Bethesda proposals for classification of nonlymphoid hematopoietic neoplasms in mice. Blood. 2002;100:238-245.
17. Iwasaki M, Kuwata T, Yamazaki Y, et al. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood. 2005;105:784-793.
18. Heitjan DF, Manni A, Santen RJ. Statiscal analysis of in vivo tumor growth experiments. Cancer Res. 1993;53:6042-6050.
19. Du Y, Jenkins NA, Copeland NG. Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells. Blood. 2005;106:3932-3939.
20. Copeland NG. RTCGD: Retroviral Tagged Cancer Gene Database. http://genome2.ncifcrf.gov/RTCGD/. Accessed June 2006.
21. Center for Biomolecular Science and Engineering. BLAT. http://www.genome.ucsc.edu/. Accessed June 2006.
22. Bartholomew C, Ihle JN. Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoter. Mol Cell Biol. 1991;11:1820-1828.
23. Jiang X, Hanna Z, Kaouass M, Girard L, Jolicoeur P. Ahi-1, a novel gene encoding a modular protein with WD-40 repeat and SH3 domains, is targeted by the Ahi-1 and Mis-2 provirus integrations. J Virol. 2002;47:9046-9059.
24. Buonamici S, Li D, Chi Y, et al. EVI1 induces myelodysplastic syndrome in mice. J Clin Invest. 2004;114:713-719.
25. Grosshans J, Wieschaus E. A genetic link between morphogenesis and cell division during formation of the ventral furrow in drosophila. Cell. 2000;101:523-531.
26. Mata J, Curado S, Ephrussi A, Rorth P. Tribbles coordinates mitosis and morphogenesis in drosophila by regulating String/CDC25 proteolysis. Cell. 2000;101:511-522.
27. Kiss-Toth E, Bagstaff SM, Sung HY, et al. Human Tribbles, a protein family controlling mitogen-activated protein kinase cascades. J Biol Chem. 2004;279:42703-42708.
28. Su AI, Cooke MP, Ching KA, et al. Large-scale analysis of the human and mouse transcriptomes. Proc Natl Acad Sci U S A. 2002;99:4465-4470.
29. Mamo A, Krosl J, Kroon E, et al. Molecular dissection of Meis1 reveals two domains required for leukemia induction and a key role for Hoxa gene activation. Blood. 2006;108:622-629.
30. Platanias LC. Map kinase signaling pathways and hematologic malignancies. Blood. 2003;101:4667-4679.
31. Choundhary C, Muller-Tidow C, Berdel WE, Serve H. Signal transduction of oncogenic Flt3. Int J Hematol. 2005;82:93-99.
32. Kiyoi H, Naoe T. FLT3 mutations in acute myeloid leukemia. Methods Mol Med. 2006;125:189-197.
33. Morishita K, Parker DS, Mucenski ML, Jenkins NA, Copeland NG, Ihle JN. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines. Cell. 1988;54:831-840.
34. Morishita K, Parganas E, William CL, et al. Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26. Proc Natl Acad Sci U S A. 1992;89:3837-3941.
35. Levy ER, Parganas E, Morishita K, et al. DNA rearrangements proximal to the EVI1 locus associated with the 3q21q26 syndrome. Blood. 1994;83:1348-1354.
36. Yuasa H, Oike Y, Iwama A, et al. Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J. 2005;24:1978-1987.
37. Kustikova O, Fehse B, Modlich U, et al. Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. Science. 2005;308:1171-1174.
38. Ott MG, Schmidt M, Schwarzwaelder K, et al. Correction pf X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1. Nat Med. 2006;12:401-409.
39. Poirier Y, Kozak C, Jolicoeur P. Identification of a common helper provirus integration site in Abelson murine leukemia virus-induced lymphoma DNA. J Virol. 1988;62:3985-3992.
40. Jiang X, Zhao Y, Chan WY, et al. Deregulated expression in Ph+ human leukemias of AHI-1, a gene activated by insertional mutagenesis in mouse models of leukemia. Blood. 2004;103:3897-3904.
41. Hess JL, Bittner CB, Zesig DT, et al. C-Myb is an essential downstream target for homeobox mediated transformation of hematopoietic cells. Blood. 2006;108:297-304.