COP1 is a tumour suppressor that causes degradation of ETS transcription factors

Nature

Volumn 474, Issue 7351, 2011, Pages 403-408

  Vitari, Alberto C ^a,b   Leong, Kevin G ^a   Newton, Kim ^a   Yee, Cindy ^a   Oĝrourke, Karen ^a   Liu, Jinfeng ^a   Phu, Lilian ^a   Vij, Rajesh ^a   Ferrando, Ronald ^a   Couto, Suzana S ^a   Mohan, Sankar ^a   Pandita, Ajay ^a   Hongo, Jo Anne ^a   Arnott, David ^a   Wertz, Ingrid E ^a   Gao, Wei Qiang ^a,c,d   French, Dorothy M ^a   Dixit, Vishva M ^a  

^a GENENTECH INC   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ER81; TRANSCRIPTION FACTOR ETV4; TRANSCRIPTION FACTOR ETV5; UBIQUITIN PROTEIN LIGASE COP1; UNCLASSIFIED DRUG;

BIODEGRADATION; CANCER; CELL ORGANELLE; FUNCTIONAL MORPHOLOGY; GENE EXPRESSION; PROTEIN; RODENT; TRANSLOCATION; TUMOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; DOWN REGULATION; EPITHELIUM CELL; GENE LOSS; GENE MUTATION; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; PROSTATE CANCER; PROSTATE HYPERTROPHY; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN MOTIF; RAT;

AMINO ACID MOTIFS; ANIMALS; CARRIER PROTEINS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; DNA-BINDING PROTEINS; HUMANS; MALE; MICE; NUCLEAR PROTEINS; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-ETS; PTEN PHOSPHOHYDROLASE; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 79959192993     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10005     Document Type: Article

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