-
1
-
-
3543141112
-
Identification of a commonly amplified 4.3 Mb region with overexpression of C8FW, but not MYC in MYC-containing double minutes in myeloid malignancies
-
DOI 10.1093/hmg/ddh164
-
Storlazzi CT, Fioretos T, Paulsson K, et al. Identification of a commonly amplified 4.3-Mb region with overexpression of C8FW, but not MYC, in MYC-containing double minutes in myeloid malignancies. Hum Mol Genet. 2004;13(14):1479-1485. (Pubitemid 39023056)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.14
, pp. 1479-1485
-
-
Storlazzi, C.T.1
Fioretos, T.2
Paulsson, K.3
Strombeck, B.4
Lassen, C.5
Ahlgren, T.6
Juliusson, G.7
Mitelman, F.8
Rocchi, M.9
Johansson, B.10
-
2
-
-
33751073965
-
Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia
-
Keeshan K, He Y, Wouters BJ, et al. Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia. Cancer Cell. 2006;10(5):401-411.
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 401-411
-
-
Keeshan, K.1
He, Y.2
Wouters, B.J.3
-
3
-
-
38449096741
-
Gene expression profile related to prognosis of acute myeloid leukemia
-
Park MH, Cho SA, Yoo KH, et al. Gene expression profile related to prognosis of acute myeloid leukemia. Oncol Rep. 2007;18(6):1395-1402.
-
(2007)
Oncol Rep
, vol.18
, Issue.6
, pp. 1395-1402
-
-
Park, M.H.1
Cho, S.A.2
Yoo, K.H.3
-
4
-
-
34247391073
-
Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis
-
Jin G, Yamazaki Y, Takuwa M, et al. Trib1 and Evi1 cooperate with Hoxa and Meis1 in myeloid leukemogenesis. Blood. 2007;109(9):3998-4005.
-
(2007)
Blood
, vol.109
, Issue.9
, pp. 3998-4005
-
-
Jin, G.1
Yamazaki, Y.2
Takuwa, M.3
-
5
-
-
35348896184
-
Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1
-
Wouters BJ, Jorda MA, Keeshan K, et al. Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1. Blood. 2007;110(10):3706-3714.
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3706-3714
-
-
Wouters, B.J.1
Jorda, M.A.2
Keeshan, K.3
-
6
-
-
0023713376
-
Acute myeloid leukemia with T-lymphoid features: A distinct biologic and clinical entity
-
Cross AH, Goorha RM, Nuss R, et al. Acute myeloid leukemia with T-lymphoid features: a distinct biologic and clinical entity. Blood. 1988;72(2):579-587.
-
(1988)
Blood
, vol.72
, Issue.2
, pp. 579-587
-
-
Cross, A.H.1
Goorha, R.M.2
Nuss, R.3
-
7
-
-
18544396997
-
Mouse NIPK interacts with ATF4 and affects its transcriptional activity
-
DOI 10.1016/S0014-4827(03)00070-3
-
Ord D, Ord T. Mouse NIPK interacts with ATF4 and affects its transcriptional activity. Exp Cell Res. 2003;286(2):308-320. (Pubitemid 36566443)
-
(2003)
Experimental Cell Research
, vol.286
, Issue.2
, pp. 308-320
-
-
Ord, D.1
Ord, T.2
-
8
-
-
0037697247
-
SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription
-
Wu M, Xu LG, Zhai Z, Shu HB. SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription. J Biol Chem. 2003;278(29):27072-27079.
-
(2003)
J Biol Chem
, vol.278
, Issue.29
, pp. 27072-27079
-
-
Wu, M.1
Xu, L.G.2
Zhai, Z.3
Shu, H.B.4
-
9
-
-
33845871714
-
TRB3 interacts with CtIP and is overexpressed in certain cancers
-
Xu J, Lv S, Qin Y, et al. TRB3 interacts with CtIP and is overexpressed in certain cancers. Biochim Biophys Acta. 2007;1770(2):273-278.
-
(2007)
Biochim Biophys Acta
, vol.1770
, Issue.2
, pp. 273-278
-
-
Xu, J.1
Lv, S.2
Qin, Y.3
-
10
-
-
5644285309
-
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades
-
Kiss-Toth E, Bagstaff SM, Sung HY, et al. Human tribbles, a protein family controlling mitogen-activated protein kinase cascades. J Biol Chem. 2004;279(41):42703-42708.
-
(2004)
J Biol Chem
, vol.279
, Issue.41
, pp. 42703-42708
-
-
Kiss-Toth, E.1
Bagstaff, S.M.2
Sung, H.Y.3
-
11
-
-
0038242819
-
TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
-
Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science. 2003;300(5625):1574- 1577.
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1574-1577
-
-
Du, K.1
Herzig, S.2
Kulkarni, R.N.3
Montminy, M.4
-
12
-
-
33745498417
-
TRB3 links the E3 ubiquitin ligase, COP1, to lipid metabolism
-
Qi L, Heredia JE, Altarejos JY, et al. TRB3 links the E3 ubiquitin ligase, COP1, to lipid metabolism. Science. 2006;312(5781):1763-1766.
-
(2006)
Science
, vol.312
, Issue.5781
, pp. 1763-1766
-
-
Qi, L.1
Heredia, J.E.2
Altarejos, J.Y.3
-
13
-
-
33845692825
-
Tribbles: A family of kinase-like proteins with potent signalling regulatory function
-
Hegedus Z, Czibula A, Kiss-Toth E. Tribbles: a family of kinase-like proteins with potent signalling regulatory function. Cell Sign. 2007;19:238-280.
-
(2007)
Cell Sign
, vol.19
, pp. 238-280
-
-
Hegedus, Z.1
Czibula, A.2
Kiss-Toth, E.3
-
14
-
-
0029020282
-
Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
-
Hanks SK, Hunter T. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 1995;9(8):576-596.
-
(1995)
FASEB J
, vol.9
, Issue.8
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
15
-
-
0030768532
-
Characterization of a phosphoprotein whose mRNA is regulated by the mitogenic pathways in dog thyroid cells
-
Wilkin F, Suarez-Huerta N, Robaye B, et al. Characterization of a phosphoprotein whose mRNA is regulated by the mitogenic pathways in dog thyroid cells. Eur J Biochem. 1997;248(3):660-668. (Pubitemid 27400018)
-
(1997)
European Journal of Biochemistry
, vol.248
, Issue.3
, pp. 660-668
-
-
Wilkin, F.1
Suarez-Huerta, N.2
Robaye, B.3
Peetermans, J.4
Libert, F.5
Dumont, J.E.6
Maenhaut, C.7
-
16
-
-
0034716888
-
A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila
-
Grosshans J, Wieschaus E. A genetic link between morphogenesis and cell division during formation of the ventral furrow in Drosophila. Cell. 2000;101(5):523-531.
-
(2000)
Cell
, vol.101
, Issue.5
, pp. 523-531
-
-
Grosshans, J.1
Wieschaus, E.2
-
17
-
-
0037954623
-
SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia
-
Bowers AJ, Scully S, Boylan JF. SKIP3, a novel Drosophila tribbles ortholog, is overexpressed in human tumors and is regulated by hypoxia. Oncogene. 2003;22(18):2823-2835.
-
(2003)
Oncogene
, vol.22
, Issue.18
, pp. 2823-2835
-
-
Bowers, A.J.1
Scully, S.2
Boylan, J.F.3
-
18
-
-
34547577752
-
Survival factor withdrawal-induced apoptosis of TF-1 cells involves a TRB2-Mcl-1 axis-dependent pathway
-
Lin KR, Lee SF, Hung CM, Li CL, Yang-Yen HF, Yen JJ. Survival factor withdrawal-induced apoptosis of TF-1 cells involves a TRB2-Mcl-1 axis-dependent pathway. J Biol Chem. 2007;282(30):21962-21972.
-
(2007)
J Biol Chem
, vol.282
, Issue.30
, pp. 21962-21972
-
-
Lin, K.R.1
Lee, S.F.2
Hung, C.M.3
Li, C.L.4
Yang-Yen, H.F.5
Yen, J.J.6
-
19
-
-
27644582893
-
Probing tumor phenotypes using stable and regulated synthetic microRNA precursors
-
Dickins RA, Hemann MT, Zilfou JT, et al. Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat Genet. 2005;37(11):1289-1295.
-
(2005)
Nat Genet
, vol.37
, Issue.11
, pp. 1289-1295
-
-
Dickins, R.A.1
Hemann, M.T.2
Zilfou, J.T.3
-
20
-
-
51349169034
-
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia
-
Chiang MY, Xu L, Shestova O, et al. Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. J Clin Invest. 2008;118(9):3181-3194.
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 3181-3194
-
-
Chiang, M.Y.1
Xu, L.2
Shestova, O.3
-
21
-
-
36749099423
-
Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia
-
Keeshan K, Shestova O, Ussin L, Pear WS. Tribbles homolog 2 (Trib2) and HoxA9 cooperate to accelerate acute myelogenous leukemia. Blood Cells Mol Dis. 2008;40(1):119-121.
-
(2008)
Blood Cells Mol Dis
, vol.40
, Issue.1
, pp. 119-121
-
-
Keeshan, K.1
Shestova, O.2
Ussin, L.3
Pear, W.S.4
-
22
-
-
0032126633
-
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
-
Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J. 1998;17(13):3714-3725.
-
(1998)
EMBO J
, vol.17
, Issue.13
, pp. 3714-3725
-
-
Kroon, E.1
Krosl, J.2
Thorsteinsdottir, U.3
Baban, S.4
Buchberg, A.M.5
Sauvageau, G.6
-
23
-
-
0032796188
-
The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells
-
Thorsteinsdottir U, Krosl J, Kroon E, Haman A, Hoang T, Sauvageau G. The oncoprotein E2A-Pbx1a collaborates with Hoxa9 to acutely transform primary bone marrow cells. Mol Cell Biol. 1999;19(9):6355-6366.
-
(1999)
Mol Cell Biol
, vol.19
, Issue.9
, pp. 6355-6366
-
-
Thorsteinsdottir, U.1
Krosl, J.2
Kroon, E.3
Haman, A.4
Hoang, T.5
Sauvageau, G.6
-
24
-
-
41249103144
-
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells
-
Kirstetter P, Schuster MB, Bereshchenko O, et al. Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells. Cancer Cell. 2008;13(4):299-310.
-
(2008)
Cancer Cell
, vol.13
, Issue.4
, pp. 299-310
-
-
Kirstetter, P.1
Schuster, M.B.2
Bereshchenko, O.3
-
25
-
-
22344437854
-
Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage
-
Porse BT, Bryder D, Theilgaard-Monch K, et al. Loss of C/EBP alpha cell cycle control increases myeloid progenitor proliferation and transforms the neutrophil granulocyte lineage. J Exp Med. 2005;202(1):85-96.
-
(2005)
J Exp Med
, vol.202
, Issue.1
, pp. 85-96
-
-
Porse, B.T.1
Bryder, D.2
Theilgaard-Monch, K.3
-
26
-
-
35348908269
-
Transcriptional dysregulation during myeloid transformation in AML
-
Pabst T, Mueller BU. Transcriptional dysregulation during myeloid transformation in AML. Oncogene. 2007;26(47):6829-6837.
-
(2007)
Oncogene
, vol.26
, Issue.47
, pp. 6829-6837
-
-
Pabst, T.1
Mueller, B.U.2
-
27
-
-
0041737609
-
Transcription activation function of C/EBPalpha is required for induction of granulocytic differentiation
-
Keeshan K, Santilli G, Corradini F, Perrotti D, Calabretta B. Transcription activation function of C/EBPalpha is required for induction of granulocytic differentiation. Blood. 2003;102(4):1267-1275.
-
(2003)
Blood
, vol.102
, Issue.4
, pp. 1267-1275
-
-
Keeshan, K.1
Santilli, G.2
Corradini, F.3
Perrotti, D.4
Calabretta, B.5
-
28
-
-
34548259466
-
TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta
-
Naiki T, Saijou E, Miyaoka Y, Sekine K, Miyajima A. TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta. J Biol Chem. 2007;282(33):24075-24082.
-
(2007)
J Biol Chem
, vol.282
, Issue.33
, pp. 24075-24082
-
-
Naiki, T.1
Saijou, E.2
Miyaoka, Y.3
Sekine, K.4
Miyajima, A.5
-
29
-
-
34748924120
-
TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity
-
Bezy O, Vernochet C, Gesta S, Farmer SR, Kahn CR. TRB3 blocks adipocyte differentiation through the inhibition of C/EBPbeta transcriptional activity. Mol Cell Biol. 2007;27(19):6818-6831.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.19
, pp. 6818-6831
-
-
Bezy, O.1
Vernochet, C.2
Gesta, S.3
Farmer, S.R.4
Kahn, C.R.5
-
30
-
-
77956495743
-
Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia
-
Dedhia PH, Keeshan K, Uljon S, et al. Differential ability of Tribbles family members to promote degradation of C/EBPalpha and induce acute myelogenous leukemia. Blood. 2010;116(8):1321-1328.
-
(2010)
Blood
, vol.116
, Issue.8
, pp. 1321-1328
-
-
Dedhia, P.H.1
Keeshan, K.2
Uljon, S.3
-
31
-
-
0030867904
-
Interleukin 3-dependent survival by the Akt protein kinase
-
Songyang Z, Baltimore D, Cantley LC, Kaplan DR, Franke TF. Interleukin 3-dependent survival by the Akt protein kinase. Proc Natl Acad Sci U S A. 1997;94(21):11345-11350.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.21
, pp. 11345-11350
-
-
Songyang, Z.1
Baltimore, D.2
Cantley, L.C.3
Kaplan, D.R.4
Franke, T.F.5
-
32
-
-
0034161391
-
Activation of Akt kinase by granulocyte colony-stimulating factor (G-CSF): Evidence for the role of a tyrosine kinase activity distinct from the Janus kinases
-
Dong F, Larner AC. Activation of Akt kinase by granulocyte colony-stimulating factor (G-CSF): evidence for the role of a tyrosine kinase activity distinct from the Janus kinases. Blood. 2000;95(5):1656-1662.
-
(2000)
Blood
, vol.95
, Issue.5
, pp. 1656-1662
-
-
Dong, F.1
Larner, A.C.2
-
33
-
-
77952672913
-
Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells
-
Zanella F, Renner O, Garcia B, et al. Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells. Oncogene. 2010;29(20):2973-2982.
-
(2010)
Oncogene
, vol.29
, Issue.20
, pp. 2973-2982
-
-
Zanella, F.1
Renner, O.2
Garcia, B.3
-
34
-
-
77950951853
-
Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia
-
Gilby DC, Sung HY, Winship PR, Goodeve AC, Reilly JT, Kiss-Toth E. Tribbles-1 and -2 are tumour suppressors, down-regulated in human acute myeloid leukaemia. Immunol Lett. 2010;130(1-2):115-124.
-
(2010)
Immunol Lett
, vol.130
, Issue.1-2
, pp. 115-124
-
-
Gilby, D.C.1
Sung, H.Y.2
Winship, P.R.3
Goodeve, A.C.4
Reilly, J.T.5
Kiss-Toth, E.6
-
35
-
-
2342447397
-
The ubiquitin ligase COP1 is a critical negative regulator of p53
-
Dornan D, Wertz I, Shimizu H, et al. The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature. 2004;429(6987):86-92.
-
(2004)
Nature
, vol.429
, Issue.6987
, pp. 86-92
-
-
Dornan, D.1
Wertz, I.2
Shimizu, H.3
-
36
-
-
0038165532
-
Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity
-
Bianchi E, Denti S, Catena R, et al. Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity. J Biol Chem. 2003;278(22):19682-19690.
-
(2003)
J Biol Chem
, vol.278
, Issue.22
, pp. 19682-19690
-
-
Bianchi, E.1
Denti, S.2
Catena, R.3
-
37
-
-
17744363445
-
Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength
-
Izon DJ, Punt JA, Xu L, et al. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength. Immunity. 2001;14(3):253-264.
-
(2001)
Immunity
, vol.14
, Issue.3
, pp. 253-264
-
-
Izon, D.J.1
Punt, J.A.2
Xu, L.3
|