Identification and dose dependency of ibuprofen biliary metabolites in rainbow trout

Chemosphere

Volumn 93, Issue 9, 2013, Pages 1789-1795

  Brozinski, Jenny Maria ^a   Lahti, Marja ^b   Oikari, Aimo ^b   Kronberg, Leif ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b UNIVERSITY OF JYVÄSKYLÄ   (Finland)

Author keywords

Biotransformation; Ibuprofen; Metabolites; Pharmaceutical; Rainbow trout

Indexed keywords

AMINO ACIDS; BIOACCUMULATION; BIOCONVERSION; BIOMOLECULES; DRUG PRODUCTS; FISH;

ANTI-INFLAMMATORY DRUGS; BIO-CONCENTRATION FACTORS; BIOTRANSFORMATION; IBUPROFEN; ION TRAP MASS ANALYZERS; RAINBOW TROUT; RAINBOW TROUTS (ONCORHYNCHUS MYKISS); TIME-OF-FLIGHT MASS ANALYZER;

METABOLITES;

DRUG METABOLITE; GLUCURONIDE; IBUPROFEN; IBUPROFEN DERIVATIVE; TAURINE DERIVATIVE;

BIOACCUMULATION; CONCENTRATION (COMPOSITION); DRUG; MARINE ECOSYSTEM; METABOLITE; POLLUTION EXPOSURE; SALMONID;

ANIMAL EXPERIMENT; ARTICLE; BIOTRANSFORMATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG BIOAVAILABILITY; DRUG EXCRETION; DRUG IDENTIFICATION; DRUG METABOLISM; ENVIRONMENTAL IMPACT ASSESSMENT; LIQUID CHROMATOGRAPHY; NONHUMAN; QUADRUPOLE MASS SPECTROMETRY; RAINBOW TROUT; WASTE WATER MANAGEMENT; WATER CONTAMINATION;

ONCORHYNCHUS MYKISS;

BIOTRANSFORMATION; IBUPROFEN; METABOLITES; PHARMACEUTICAL; RAINBOW TROUT;

ANIMALS; BILE; BIOTRANSFORMATION; DOSE-RESPONSE RELATIONSHIP, DRUG; IBUPROFEN; ONCORHYNCHUS MYKISS; WATER POLLUTANTS, CHEMICAL;

EID: 84886394018     PISSN: 00456535     EISSN: 18791298     Source Type: Journal    
DOI: 10.1016/j.chemosphere.2013.06.018     Document Type: Article

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