Stereoselectivity of ibuprofen metabolism and pharmacokinetics following the administration of the racemate to healthy volunteers

Xenobiotica

Volumn 32, Issue 8, 2002, Pages 683-697

  Tan, S C ^a   Patel, B K ^a   Jackson, S H D ^b   Swift, C G ^b   Hutt, A J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYIBUPROFEN; CARBOXYIBUPROFEN; GLUCURONIC ACID; IBUPROFEN; IBUPROFEN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOGRAPHY; CONJUGATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG URINE LEVEL; ENANTIOMER; HUMAN; METABOLITE; RACEMIC MIXTURE; STATISTICAL SIGNIFICANCE; STEREOCHEMISTRY; URINARY EXCRETION;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; IBUPROFEN; MALE; MODELS, CHEMICAL; OXYGEN; STEREOISOMERISM; TIME FACTORS;

EID: 0036692471     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250210142994     Document Type: Article

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