Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters

Water Research

Volumn 39, Issue 11, 2005, Pages 2219-2228

  Lindqvist, Niina ^a   Tuhkanen, Tuula ^b   Kronberg, Leif ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

Discharge to rivers; Environmental risk; Pharmaceuticals; Sewage treatment plant influent and effluent

Indexed keywords

AQUACULTURE; CHEMICALS REMOVAL (WATER TREATMENT); DRUG PRODUCTS; ENVIRONMENTAL IMPACT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHASE SEPARATION; RIVERS; SEWAGE TREATMENT;

BEZAFIBRATE; DICLOFENAC; KETOPROFEN; SOLID PHASE EXTRACTIONS;

SEWAGE;

BEZAFIBRATE; DICLOFENAC; IBUPROFEN; KETOPROFEN; NAPROXEN; RIVER WATER;

ORGANIC COMPOUND; SEWAGE OUTFALL; WATER POLLUTION; WATER QUALITY;

ANALYTIC METHOD; ARTICLE; DRUG DETERMINATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; PREDICTION; PRIORITY JOURNAL; RISK ASSESSMENT; SEASONAL VARIATION; SEPARATION TECHNIQUE; SEWAGE DISPOSAL; SEWAGE TREATMENT PLANT; SOLID PHASE EXTRACTION; WATER ANALYSIS; WATER CONTAMINATION; WATER POLLUTION;

EID: 20544460624     PISSN: 00431354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.watres.2005.04.003     Document Type: Article

References (19)

1. R. Andreozzi, R. Marotta, and N. Paxéus Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment Chemosphere 50 10 2003 1319 1330
2. G.R. Boyd, H. Reemtsma, D.A. Grimm, and S. Mitra Pharmaceuticals and personal care products (PPCPs) in surface and treated waters in Louisiana, USA and Ontario, Canada Sci. Total Environ. 311 1-3 2003 135 149
3. H.-R. Buser, T. Poiger, and M.D. Müller Occurrence and environmental behavior of the chiral pharmaceutical drug ibuprofen in surface waters and in wastewaters Environ. Sci. Technol. 33 15 1999 2529 2535
4. B. Ferrari, N. Paxéus, R. Lo Giudice, A. Pollio, and J. Garric Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac Ecotoxicol Environ. Safety 55 3 2003 359 370
5. B. Halling-Sørensen, S.N. Nielsen, P.F. Lannzky, F. Ingerslev, H.C. Holten Lützhøft, and S.E. Jørgensen Occurrence, fate and effects of pharmaceutical substances in the environment-a review Chemosphere 36 2 1998 357 393
6. T. Heberer Tracking persistent pharmaceutical residues from municipal sewage to drinking water J. Hydrol. 266 3-4 2002 175 189
7. O.A.H. Jones, N. Voulvoulis, and J.N. Lester Aquatic environmental assessment of the top 25 English prescription pharmaceuticals Water Res. 36 20 2002 5013 5022
8. S.J. Khan, and J.E. Ongerth Modelling of pharmaceutical residues in Australian sewage by quantities of use and fugacity calculations Chemosphere 54 3 2004 355 367
9. National Agency for Medicines, 2002. Suomen lääketilasto/ Finnish Statistics on Medicines 2002. Available in www format: URL: http://www.nam.fi/laakeinformaatio/laakekulutus/laaketilasto.html. Visited 3.11.2003.
10. Product Monograph for bezalip (bezafibrate), 2003. Lipid metabolism regulator drug. Available in www format: URL: http://www.rochecanada.com/. Visited 12.2.2003.
11. SRC PhysProp Database, 2003. Interactive PhysProp Database Demo. Available at www format: URL: http://esc.syrres.com/interkow/physdemo.htm. Visited 2.11.2003.
12. B. Soulet, A. Tauxe, and J. Tarradellas Analysis of acidic drugs in Swiss wastewaters Int. J. Environ. Anal. Chem. 82 10 2002 659 667
13. M. Stumpf, T. Ternes, R.-D. Wilken, S.V. Rodrigues, and W. Baumann Polar drug residues in sewage and natural waters in the state of Rio de Janeiro, Brazil Sci. Total Environ. 225 1-2 1999 135 141
14. T. Ternes Occurrence of drugs in German sewage treatment plants and rivers Water Res. 32 11 1998 3245 3260
15. 2- sympathomimetics in aqueous matrices using GC/MS and LC/MS/MS Fresenius J. Anal. Chem. 362 3 1998 329 340
16. TGD Technical Guidance Document in support of council directive 93/67/EEC on risk assessment for new notified substances and commission regulation (EC) 1488/94 on risk assessment for existing substances 1996 Office for Official Publications of the European Communities Luxembourg
17. C. Tixier, H.P. Singer, S. Oellers, and S.R. Müller Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters Environ. Sci. Technol. 37 6 2003 1061 1068
18. US EPA, 2003. ECOSAR, Ecological Structure Activity Relationships program. Downloaded (3.11.2003) from the www page: http://www.epa.gov/oppt/ newchems/21ecosar.htm.
19. M. Winkler, J.R. Lawrence, and T.R. Neu Selective degradation of ibuprofen and clofibric acid in two model river biofilm systems Water Res. 35 11 2001 3197 3205