Mechanisms of andrographolide-induced platelet apoptosis in human platelets: Regulatory roles of the extrinsic apoptotic pathway

Phytotherapy Research

Volumn 27, Issue 11, 2013, Pages 1671-1677

  Lien, Li Ming ^a   Su, Cheng Chen ^b   Hsu, Wen Hsien ^c   Lu, Wan Jung ^d   Chung, Chi Li ^d,e   Yen, Ting Lin ^d   Chiu, Hou Chang ^a   Sheu, Joen Rong ^d   Lin, Kuan Hung ^a,d  

^a SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^b YUAN'S GENERAL HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

andrographolide; Bid; caspase 3; caspase 8; mitochondrial membrane potential; platelets

Indexed keywords

ANDROGRAPHOLIDE; CASPASE 3; CASPASE 8; HEME OXYGENASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN BID;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LIFESPAN; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION;

ANDROGRAPHIS PANICULATA;

ANDROGRAPHOLIDE; BID; CASPASE-3; CASPASE-8; MITOCHONDRIAL MEMBRANE POTENTIAL; PLATELETS;

ANDROGRAPHIS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOOD PLATELETS; CASPASE 3; CASPASE 8; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PLANT LEAVES; PLATELET ACTIVATION; PLATELET AGGREGATION; SIGNAL TRANSDUCTION;

EID: 84886301449     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4911     Document Type: Article

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