Probing structural adaptivity at PPI interfaces with small molecules

Drug Discovery Today: Technologies

Volumn 10, Issue 4, 2013, Pages

  Wilson, Christopher G ^a   Arkin, Michelle R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLAMIDE; AMINE; AROMATIC CARBOXYLIC ACID; CARBENE; CARBOXYLIC ACID; CHLORIDE; CYSTEINE; DISULFIDE; GLUTAMIC ACID; INTERLEUKIN 2; LIGAND; LYSINE; MERCAPTAMINE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN; THIOL;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CELLULAR DISTRIBUTION; CRYSTALLOGRAPHY; DRUG SCREENING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MOLECULE; NUCLEAR MAGNETIC RESONANCE; PHOSPHORYLATION AND DEPHOSPHORYLATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; X RAY CRYSTALLOGRAPHY;

DRUG DISCOVERY; INTERLEUKIN-2; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN INTERACTION MAPPING; PROTEIN-SERINE-THREONINE KINASES;

EID: 84886290829     PISSN: None     EISSN: 17406749     Source Type: Journal    
DOI: 10.1016/j.ddtec.2012.10.009     Document Type: Review

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