Discovery and characterization of cooperative ligand binding in the adaptive region of interleukin-2

Biochemistry

Volumn 42, Issue 21, 2003, Pages 6475-6483

  Hyde, Jennifer ^a   Braisted, Andrew C ^a   Randal, Mike ^a   Arkin, Michelle R ^a  

^a Sunesis Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR RECOGNITION;

CHEMICAL BONDS; MOLECULAR BIOLOGY; PROTEINS; SURFACE PLASMON RESONANCE; X RAY CRYSTALLOGRAPHY;

HORMONES;

CYTOKINE; INTERLEUKIN 2; LIGAND;

ARTICLE; BINDING SITE; CYTOKINE RELEASE; DISULFIDE BOND; DYNAMICS; ENERGY; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SURFACE PLASMON RESONANCE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; BINDING, COMPETITIVE; BIOCHEMISTRY; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INTERLEUKIN-2; LIGANDS; MASS SPECTROMETRY; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; SURFACE PLASMON RESONANCE; THERMODYNAMICS; TIME FACTORS;

EID: 0038010557     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034138g     Document Type: Article

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