Experiences in fragment-based lead discovery

Methods in Enzymology

Volumn 493, Issue , 2011, Pages 509-531

  Hubbard, Roderick E ^a,b   Murray, James B ^a  

^a Vernalis PLC   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; LEAD; PEPTIDYLPROLYL ISOMERASE PIN1; PROTEIN KINASE; PROTEIN KINASE 1; PROTEIN KINASE 2; PROTEIN KINASE 3; RESORCINOL; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION (PARAMETERS); COST EFFECTIVENESS ANALYSIS; DIFFERENTIAL SCANNING FLUORIMETRY; ENZYME ACTIVITY; FLUOROMETRY; INTERMETHOD COMPARISON; LIGAND BINDING; MOLECULAR LIBRARY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SURFACE PLASMON RESONANCE; X RAY CRYSTALLOGRAPHY;

EID: 79952429629     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-381274-2.00020-0     Document Type: Chapter

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