Unraveling toxicological mechanisms and predicting toxicity classes with gene dysregulation networks

Journal of Applied Toxicology

Volumn 33, Issue 12, 2013, Pages 1407-1415

  Pronk, Tessa E ^a,b   Van Someren, Eugene P ^c   Stierum, Rob H ^c   Ezendam, Janine ^a   Pennings, Jeroen L A ^a  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c TNO   (Netherlands)

Author keywords

Biomarkers; Classification; Network; Regulation; Skin sensitization; Toxicogenomics

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; BIOLOGICAL MARKER; HEME OXYGENASE 1; IRRITANT AGENT; PROTEIN; PROTEIN HSPA1B; PROTEIN OXSR1; PROTEIN PPP1R15A; PROTEIN ZFAND2A; TRANSCRIPTION FACTOR MAFF; TRISTETRAPROLIN; UNCLASSIFIED DRUG;

ARTICLE; CLASSIFICATION; GENE DYSREGULATION NETWORK; GENE EXPRESSION; GENE FUNCTION; GENE REGULATORY NETWORK; GENETIC ANALYSIS; HEAT SHOCK; HUMAN; MEASUREMENT ACCURACY; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SKIN CELL; SKIN SENSITIZATION; STRESS; TOXICOGENETICS;

BIOMARKERS; CLASSIFICATION; NETWORK; REGULATION; SKIN SENSITIZATION; TOXICOGENOMICS;

ALLERGENS; BIOLOGICAL MARKERS; CELL LINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HUMANS; IRRITANTS; PREDICTIVE VALUE OF TESTS; TOXICOGENETICS;

EID: 84886090148     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2800     Document Type: Article

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