Application of genomic biomarkers to predict increased lung tumor incidence in 2-year rodent cancer bioassays

Toxicological Sciences

Volumn 97, Issue 1, 2007, Pages 55-64

  Thomas, Russell S ^a   Pluta, Linda ^a   Yang, Longlong ^a   Halsey, Thomas A ^a,b  

^a HAMNER INSTITUTES FOR HEALTH SCIENCES   (United States)

^b Almac Sciences   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DIBROMOETHANE; 1,5 NAPHTHALENEDIAMINE; 2 CHLOROMETHYLPYRIDINE; 4 NITROANTHRANILIC ACID; BENZENE; BENZOFURAN; CARCINOGEN; COUMARIN; DIBROMONEOPENTYL GLYCOL; DIMPYLATE; MALATHION; N (1 NAPHTHYL)ETHYLENEDIAMINE; N (HYDROXYMETHYL)ACRYLAMIDE; QUINTOZENE; UNCLASSIFIED DRUG; MESSENGER RNA; TUMOR MARKER;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CARCINOGENICITY; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; INCIDENCE; LUNG DEVELOPMENT; LUNG TUMOR; MARKER GENE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PREDICTION; SENSITIVITY AND SPECIFICITY; XENOBIOTIC METABOLISM; ALGORITHM; ANIMAL; CARCINOGEN TESTING; CELL TRANSFORMATION; CHEMICAL STRUCTURE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; COMPARATIVE STUDY; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GENOMICS; MALE; METABOLISM; METHODOLOGY; PATHOLOGY; PREDICTION AND FORECASTING; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL MODEL; STRUCTURE ACTIVITY RELATION; TIME;

ANIMALIA; MUS; RODENTIA;

ALGORITHMS; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMICS; LUNG NEOPLASMS; MALE; MICE; MODELS, STATISTICAL; MOLECULAR STRUCTURE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 34347250516     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfm023     Document Type: Article

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