Nrf2-dependent and -independent responses to nitro-fatty acids in human endothelial cells: Identification of heat shock response as the major pathway activated by nitro-oleic acid

Journal of Biological Chemistry

Volumn 284, Issue 48, 2009, Pages 33233-33241

  Kansanen, Emilia ^a   Jyrkkänen, Henna Kaisa ^a   Volger, Oscar L ^b   Leinonen, Hanna ^a   Kivelä, Annukka M ^a   Häkkinen, Sanna Kaisa ^a   Woodcock, Steven R ^c   Schopfer, Francisco J ^c   Horrevoets, Anton J ^b   Ylä Herttuala, Seppo ^a   Freeman, Bruce A ^c   Levonen, Anna Liisa ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY ACTION; CELL SIGNALING; CYTOPROTECTIVE ACTION; DIFFERENTIAL GENE EXPRESSIONS; FATTY ACID DERIVATIVES; GLUTAMATE-CYSTEINE LIGASE; HEAT SHOCK RESPONSE; HEAT SHOCK TRANSCRIPTION FACTORS; HEAT-SHOCK; HEME OXYGENASE-1; HUMAN ENDOTHELIAL CELLS; INFLAMMATORY GENES; NITROLINOLEIC ACIDS; OXIDATIVE INJURY; REGULATED GENES; SMALL INTERFERING RNA; TRANSCRIPTIONAL PROFILING;

ACIDS; BIOACTIVITY; BLOOD VESSEL PROSTHESES; GENES; NUCLEIC ACIDS; OLEIC ACID; PLANTS (BOTANY); PORPHYRINS; RNA; SELF ASSEMBLY; SIGNALING; TRANSCRIPTION; TRANSCRIPTION FACTORS;

ENDOTHELIAL CELLS;

FATTY ACID DERIVATIVE; GLUTAMATE CYSTEINE LIGASE; HEAT SHOCK PROTEIN; HEME OXYGENASE 1; NITRO OLEIC ACID; NITROLINOLEIC ACID; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENETIC REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING;

BLOTTING, WESTERN; CELL LINE; CELLS, CULTURED; CLUSTER ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GLUTAMATE-CYSTEINE LIGASE; HEME OXYGENASE-1; HOT TEMPERATURE; HUMANS; LINOLEIC ACIDS; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NITRO COMPOUNDS; OLEIC ACIDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

EID: 70450246970     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.064873     Document Type: Article

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