Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds

Mutagenesis

Volumn 25, Issue 6, 2010, Pages 561-568

  Mathijs, K ^a,b   Brauers, K J J ^a   Jennen, D G J ^a,b   Lizarraga, D ^a,b   Kleinjans, J C S ^a,b   Van Delft, J H M ^a,b  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITRO 1,2 PHENYLENEDIAMINE; 8 QUINOLINOL; ACRYLIC ACID ETHYL ESTER; AFLATOXIN B1; ANTHRANILIC ACID; BENZO[A]PYRENE; CURCUMIN; DIMETHYLBENZ[A]ANTHRACENE; DIMETHYLNITROSAMINE; DNA; HISTONE H2AX; MITOMYCIN C; N (2 FLUORENYL)ACETAMIDE; PHENACETIN; QUERCETIN; RESORCINOL; TOXIC SUBSTANCE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CLASSIFIER; CLINICAL CLASSIFICATION; CONTROLLED STUDY; DNA DAMAGE; GENE CLUSTER; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENOME; GENOME ANALYSIS; GENOTOXICITY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; LIVER CELL; METABOLISM; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PREDICTION AND FORECASTING; PRIORITY JOURNAL; PROTEIN MODIFICATION; VALIDATION PROCESS;

ANIMALS; CARCINOGENS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CLUSTER ANALYSIS; DNA DAMAGE; FALSE POSITIVE REACTIONS; GENE EXPRESSION PROFILING; HEPATOCYTES; HISTONES; MALE; MICE; MICE, INBRED C57BL; MUTAGENICITY TESTS;

MUS;

EID: 78149369706     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/geq040     Document Type: Article

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