Integration of clinical chemistry, expression, and metabolite data leads to better toxicological class separation

Toxicological Sciences

Volumn 102, Issue 2, 2008, Pages 444-454

  Spicker, Jeppe S ^a,b   Brunak, Søren ^a   Frederiksen, Klaus S ^b   Toft, Henrik ^b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b NOVO NORDISK A S   (Denmark)

Author keywords

Clinical chemistry; Data integration; Metabonomics; Microarray; Toxicology

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; DIMETHYLNITROSAMINE; N METHYLFORMAMIDE;

ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; BIOLOGICAL MONITORING; CELL HYPERPLASIA; CLINICAL CHEMISTRY; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; INFLAMMATION; INFORMATION PROCESSING; INTEGRATION; LIVER CELL DAMAGE; LIVER NECROSIS; LIVER TOXICITY; MALE; NONHUMAN; RAT; RNA EXTRACTION; TISSUE MICROARRAY; TOXICOLOGY;

1-NAPHTHYLISOTHIOCYANATE; ALGORITHMS; ANIMALS; CLINICAL CHEMISTRY TESTS; COMPUTATIONAL BIOLOGY; DATABASE MANAGEMENT SYSTEMS; DATABASES, FACTUAL; DECISION SUPPORT TECHNIQUES; DIMETHYLNITROSAMINE; FORMAMIDES; GENE EXPRESSION; HUMANS; INFORMATION STORAGE AND RETRIEVAL; LEAST-SQUARES ANALYSIS; MODELS, STATISTICAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRINCIPAL COMPONENT ANALYSIS; RATS; RNA, MESSENGER; TOXICOLOGY; XENOBIOTICS;

RATTUS;

EID: 40949149421     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfn001     Document Type: Article

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